Antonio Noda-Cabrera

Cutaneous infection by Fusarium: successful treatment with oral voriconazole.

1 Fujimoto N, Tajima S, Ishibashi A. Facial lichen striatus: successful treatment with tacrolimus ointment. Br J Dermatol 2003; 148: 587–90. 2 Sorgentini C, Allevato MA, Dahbar M, Cabrera H. Liquen estriado del adulto. Tratamiento con tacrolimus tópico. Actualizaciones Terapéuticas Dermatológicas y Estéticas 2003; 26: 44–50. 3 Taieb A, el-Youbi A, Grosshans E, Maleville J. Lichen striatus: a Blaschko linear acquired inflammatory skin eruption. J Am Acad Dermatol 1991; 25: 637–42. 4 Michel JL, Wolf F, Fond L, Cambazard F. Lichen striatus in children and blaschkitis in adults. Ann Dermatol Venereol 1997; 124: 187– 91. 5 Kaliakatsou F, Hodgson TA, Lewsey J et al. Management of recalcitrant ulcerative oral lichen planus with topical tacrolimus. J Am Acad Dermatol 2002; 46: 35–41.

Safety of long-term treatment with cyclosporin A in resistant chronic plaque psoriasis: a retrospective case series.

Background  An intermittent short course of cyclosporin A (CyA) therapy is a good choice in the treatment of severe psoriasis. Nevertheless, some severe or resistant patients might benefit from long‐term treatment. Adverse effects of long‐term use of CyA are investigated and the results are compared with the literature.

The role of psychological factors in palmoplantar pustulosis

Objective   The aim of the present study was to find out whether emotional stress is related to palmoplantar pustulosis (PPP).

Coincidental presentation of vitiligo and psoriasis in a patient with polyglandular autoimmune syndrome

T.Yanagi, N. Kato, N. Yamane, R. Osawa, K. Isu* and W. Ichimura† Departments of Dermatology, *Orthopaedic Surgery and Department of †Radiology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan. Dr Teruki Yanagi, MD, Department of Dermatology, National Hospital Organization Hokkaido Cancer Center, Kikusui 4-2, Shiroishi-ku, 0030804, Sapporo, Japan. E-mail: yanagi@med.hokudai.ac.jp Conflict of interest: none declared. Accepted for publication 29 January 2007

Lichen striatus in an adult successfully treated with pimecrolimus cream

1140 JEADV 2006, 20, 1133–1167

Plantar collagenoma in a karate practitioner

Editor Collagenomas are connective tissue nevi of the collagen type, which usually begin during childhood. Chronic traumatisms related to recreational or occupational activities may play a role in the development of these asymptomatic dermal nodules in adult patients. They are often related to sport activities, so are called ‘athlete’s nodules’. An isolated plantar collagenoma in a karate practitioner is reported. A 37-year-old white man presented with an asymptomatic nodule on his right sole. It had appeared 2 months earlier and it had enlarged slowly. No personal or family history of collagenomas or Dupuytren’s disease was found. Physical examination revealed a firm, flesh-coloured, intradermal nodule, 3.5 cm in diameter, on the metatarsal plantar surface of the right foot (fig. 1). The overlying cutaneous surface was normal. No other nodules located elsewhere on this cutaneous surface could be found. A biopsy specimen was performed and histological examination showed an increased number of collagen bundles without an increased proliferation of dermal vasculature. Hyperkeratosis and mild acanthosis of the overlying epidermis were also found. A significant increase of thick collagen bundles could be observed with Masson’s trichrome stain (fig. 2). Our patient refused treatment when informed about the benign nature of his condition. Collagenomas are circumscribed hamartomatous growths of otherwise normal collagen in the dermis. 1 Acquired and inherited conditions have both been described. The hereditary type includes cerebriform collagenomas of Proteus syndrome, dermatofibrosis lenticularis disseminata in the Buschke–Ollendorf syndrome, shagreen patches in tuberous sclerosis and multiple symmetrical cutaneous nodules, which could be associated with underlying cardiac disease 2 in familial cutaneous collagenoma. Multiple and solitary collagenoma in patients with Down syndrome have also been reported. 3 The sporadic type could be classified as eruptive, isolated, or sports-related collagenomas, in respect of the number of lesions and their aetiology. 1

Localized lichen myxoedematosus (papular mucinosis) associated with morbid obesity: report of two cases

Cutaneous diseases are often found in obese patients but, to our knowledge, mucinous disorders have not been previously reported in association with obesity. Two cases of localized lichen myxoedematosus (papular mucinosis) in two women with morbid obesity are described. Both patients underwent a low‐calorie diet for a 1‐year period in one case, and for 4 months in the other one, as the only treatment. There was complete resolution of cutaneous lesions at the same time that an important weight loss was observed. Nevertheless, although spontaneous regression is not frequent, it could not be disregarded in either of these two cases.

Conjunctival Melanoma: A New Clinical and Therapeutical Approach

Melanoma involving the conjunctiva is extremely rare. Graver prognosis has been reported with primary conjunctival melanoma than with their cutaneous counterparts [Collin et al.: Aust N Z J Ophthalmol 1986;14:29–34]. Among conjunctival melanomas, two significant risk factors for tumour-related death have been identified: (i) age older than 55 years and (ii) unfavourable tumour location (caruncle, cornea, fornix, palpebral conjunctiva) [Werschnik and Lommatzsch: Am J Clin Oncol 2002;25:248–255]. Here we present a rare case of lentigo maligna involving the palpebral, bulbar conjunctiva and the caruncle. We describe dermoscopic patterns observed and the use of a novel ocular melanoma therapy with topical imiquimod.

Metastatic gastric cancer presenting as a solitary axillary cutaneous nodule.

An 84‐year‐old man, with a medical history of dilated cardiomyopathy, was admitted to our hospital with a nodular lesion in his right axilla of 6 weeks’ duration. There was no history of weight loss, nausea, or vomiting. Physical examination revealed a red–violet axillary nodule, 7 cm in diameter and 3 cm thick, with an ulcerated surface ( Fig. 1 ). A palpable right adenopathy was also found. The rest of the physical examination was normal.

An Unusual Case of Congenital Linear Eccrine Spiradenoma

Abstract:  Eccrine spiradenoma (ES) is a benign uncommon tumor of skin adnexa with a characteristic clinical and histopathological presentation. Typically, it presents as a painful, slow growing and solitary nodule on the head or upper trunk in adult patients. We report a child with linear ES which presented with asymptomatic papulonodular lesions in a blaschkoid distribution on the face. Cases reported in the literature of multiple spiradenomas are very rare and multiple linear lesions are even rarer. To date, 21 cases of linear/multiple ES have been reported. Of these, eight were in children or adolescents. We report an additional case of this rare clinical presentation and review the literature.