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Featured researches published by Antonio Pascale.


Environmental Health Perspectives | 2015

E-Waste and Harm to Vulnerable Populations: A Growing Global Problem.

Michelle Heacock; Carol Bain Kelly; Kwadwo Ansong Asante; Linda S. Birnbaum; Åke Lennart Bergman; Marie-Noel Brune; Irena Buka; David O. Carpenter; Aimin Chen; Xia Huo; Mostafa Kamel; Philip J. Landrigan; Federico Magalini; Fernando Díaz-Barriga; Maria Neira; Magdy Omar; Antonio Pascale; Mathuros Ruchirawat; Leith Sly; Peter D. Sly; Martin van den Berg; William A. Suk

Background: Electronic waste (e-waste) is produced in staggering quantities, estimated globally to be 41.8 million tonnes in 2014. Informal e-waste recycling is a source of much-needed income in many low- to middle-income countries. However, its handling and disposal in underdeveloped countries is often unsafe and leads to contaminated environments. Rudimentary and uncontrolled processing methods often result in substantial harmful chemical exposures among vulnerable populations, including women and children. E-waste hazards have not yet received the attention they deserve in research and public health agendas. Objectives: We provide an overview of the scale and health risks. We review international efforts concerned with environmental hazards, especially affecting children, as a preface to presenting next steps in addressing health issues stemming from the global e-waste problem. Discussion: The e-waste problem has been building for decades. Increased observation of adverse health effects from e-waste sites calls for protecting human health and the environment from e-waste contamination. Even if e-waste exposure intervention and prevention efforts are implemented, legacy contamination will remain, necessitating increased awareness of e-waste as a major environmental health threat. Conclusion: Global, national, and local levels efforts must aim to create safe recycling operations that consider broad security issues for people who rely on e-waste processing for survival. Paramount to these efforts is reducing pregnant women and children’s e-waste exposures to mitigate harmful health effects. With human environmental health in mind, novel dismantling methods and remediation technologies and intervention practices are needed to protect communities. Citation: Heacock M, Kelly CB, Asante KA, Birnbaum LS, Bergman AL, Bruné MN, Buka I, Carpenter DO, Chen A, Huo X, Kamel M, Landrigan PJ, Magalini F, Diaz-Barriga F, Neira M, Omar M, Pascale A, Ruchirawat M, Sly L, Sly PD, Van den Berg M, Suk WA. 2016. E-waste and harm to vulnerable populations: a growing global problem. Environ Health Perspect 124:550–555; http://dx.doi.org/10.1289/ehp.1509699


Annals of global health | 2016

E-Waste Informal Recycling: An Emerging Source of Lead Exposure in South America

Antonio Pascale; Adriana Sosa; Cristina B. Bares; Alejandra Battocletti; María José Moll; Darío Pose; Amalia Laborde; Hugo González; Gabriella Feola

BACKGROUND Primitive electronic waste (e-waste) recycling creates exposures to several hazardous substances including lead. In Uruguay, primitive recycling procedures are a significant source of lead exposure. OBJECTIVES The aim of this study was to examine lead exposure in blood lead levels (BLLs) in low-income children exposed to lead through burning cables. METHODS A sample of children and adolescents exposed to lead through burning cable activities were assessed at the Department of Toxicology in Montevideo, Uruguay, between 2010 and 2014. Soil lead levels of residences were taken shortly after their assessment. FINDINGS The final sample included 69 children and adolescents (mean age 7.89 years). More than 66% of participants had an additional source of lead exposure—manual gathering of metals—and <5% were exposed to lead through landfills or paint. Average BLLs at first consultation were 9.19 ug/dL and lower at the second measurement (5.86 μg/dL). Data from soil lead levels ranged from 650 to 19,000 mg of lead/kg of soil. The interventions conducted after the assessment included family education in the clinic and at home, indoor and outdoor remediation. We found a decrease in BLLs of 6.96 μg/dL. Older children had lower BLLs (r = −0.24; P =0.05). Statistical analyses also showed that children living in areas with higher soil lead levels had significantly higher BLLs (r = 0.50; P < 0.01). Additionally, we found greater BLLs from burning cable activities when children had been exposed to lead-based paint (r = 0.23; P < 0.1). CONCLUSION Among children exposed to e-waste recycling, the most common additional source of lead exposure was the manual gathering of metals. The average BLL among children and adolescents in this study is higher than the BLLs currently suggested in medical intervention. Future research should focus on exploring effective interventions to reduce lead exposure among this vulnerable group.


Reviews on environmental health | 2018

Prevention-intervention strategies to reduce exposure to e-waste

Michelle Heacock; B. Trottier; S. Adhikary; Kwadwo Ansong Asante; Niladri Basu; Marie-Noel Brune; Jack Caravanos; David O. Carpenter; D. Cazabon; Paromita Chakraborty; Aimin Chen; F.D. Barriga; Bret Ericson; Julius N. Fobil; B. Haryanto; Xia Huo; Tushar Kant Joshi; Philip J. Landrigan; A. Lopez; F. Magalini; P. Navasumrit; Antonio Pascale; S. Sambandam; U.S. Aslia Kamil; Leith Sly; Peter D. Sly; A. Suk; I. Suraweera; R. Tamin; E. Vicario

Abstract As one of the largest waste streams, electronic waste (e-waste) production continues to grow in response to global demand for consumer electronics. This waste is often shipped to developing countries where it is disassembled and recycled. In many cases, e-waste recycling activities are conducted in informal settings with very few controls or protections in place for workers. These activities involve exposure to hazardous substances such as cadmium, lead, and brominated flame retardants and are frequently performed by women and children. Although recycling practices and exposures vary by scale and geographic region, we present case studies of e-waste recycling scenarios and intervention approaches to reduce or prevent exposures to the hazardous substances in e-waste that may be broadly applicable to diverse situations. Drawing on parallels identified in these cases, we discuss the future prevention and intervention strategies that recognize the difficult economic realities of informal e-waste recycling.


Encyclopedia of the Anthropocene | 2018

E-waste: Environmental and Health Challenges

Antonio Pascale; C. Bares; A. Laborde

Starting in the latter portion of the 20th century, electronic waste has grown exponentially as a problem for the health of humans and the planet. This problem has a disproportionate impact on the health of vulnerable populations in developing countries. Discarded electronic devices significantly contribute to environmental pollution and harms to human health have been documented among workers and neighboring vulnerable groups including children and pregnant women who come in direct contact with toxic substances as well as through airborne exposures.


The Lancet Global Health | 2014

Networking to advance progress in children's environmental health

Peter D. Sly; Maria Neira; Gwen W. Collman; David O. Carpenter; Philip J. Landrigan; Martin van den Berg; Fernando Diaz Barriga; Mathuros Ruchirawat; Amalia Laborde; Antonio Pascale; Michelle Heacock; Marguerite T Dalmau; William A. Suk


Adicciones | 2010

Pasta base de cocaína: experiencia del Centro de Información y Asesoramiento Toxicológico

Antonio Pascale; Alba Negrín; Amalia Laborde


Revista Uruguaya de Cardiología | 2014

El consumo crónico de clorhidrato y/o pasta base de cocaína asocia envejecimiento arterial prematuro y aumento del riesgo cardiovascular

Miguel Kapitán; Ignacio Farro; Alba Negrín; Mariela Lujambio; Yanina Zócalo; Melina Pan; María Langhain; Lucía Florio; Antonio Pascale; Victoria García; Gabriela Moreira; Rodolfo Ferrando; Daniel Bia


Archive | 2015

Preliminary Study of the Effect on the Lungs Due to the Consumption of Cocaine Base Paste Estudio preliminar de la repercusión pulmonar por consumo de pasta base de cocaína

Antonio Pascale; Alba Negrín; Rocío Ormaechea; Centro de Información


Archivos de Pediatría del Uruguay | 2015

Intoxicación por anís de campo (Ocimum selloi).: A propósito de un caso

Andrés Vigna; Maríanoel Valdez; Antonio Pascale; Mario Moraes; Daniel Borbonet; Amalia Laborde


Drug and Alcohol Dependence | 2014

Trajectories of daily cigarette use from mid-adolescence to young adulthood: The role of depressive symptoms

Cristina B. Bares; Antonio Pascale

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Amalia Laborde

University of the Republic

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Cristina B. Bares

Virginia Commonwealth University

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Michelle Heacock

National Institutes of Health

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Philip J. Landrigan

Icahn School of Medicine at Mount Sinai

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Peter D. Sly

University of Queensland

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Aimin Chen

University of Cincinnati Academic Health Center

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William A. Suk

National Institutes of Health

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Kwadwo Ansong Asante

Council of Scientific and Industrial Research

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Maria Neira

World Health Organization

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