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Surgical Innovation | 2015

Miniature Surgical Robots in the Era of NOTES and LESS Dream or Reality

Apollon Zygomalas; Ioannis Kehagias; Konstantinos Giokas; Dimitrios D. Koutsouris

Laparoscopy is an established method for the treatment of numerous surgical conditions. Natural orifice transluminal endoscopic surgery (NOTES) is a novel surgical technique that uses the natural orifices of the human body as entrances to the abdominal cavity. An alternative concept of minimally invasive approach to the abdominal cavity is to insert all the laparoscopic instruments through ports using a single small incision on the abdominal wall. A suggested name for this technique is laparoendoscopic single-site surgery (LESS). Considering the technical difficulties in NOTES and LESS and the progress in informatics and robotics, the use of robots seems ideal. The aim of this study is to investigate if there is at present, a realistic possibility of using miniature robots in NOTES or LESS in daily clinical practice. An up-to-date review on in vivo surgical miniature robots is made. A Web-based research of the English literature up to March 2013 using PubMed, Scopus, and Google Scholar as search engines was performed. The development of in vivo miniature robots for use in NOTES or LESS is a reality with great advancements, potential advantages, and possible application in minimally invasive surgery in the future. However, true totally NOTES or LESS procedures on humans using miniature robots either solely or as assistance, remain a dream at present.


Journal of Laparoendoscopic & Advanced Surgical Techniques | 2012

Totally Laparoscopic Management of Gallstone Ileus—Technical Report and Review of the Literature

Apollon Zygomalas; Stavros N. Karamanakos; Ioannis Kehagias

PURPOSE Gallstone ileus is an uncommon complication of gallstone disease. It occurs in elderly patients in up to 25% of the cases. The management of gallstone ileus remains controversial. Open surgery has been the mainstay of treatment, but laparoscopic surgery has recently been used. In this study we report a case of an 87-year-old female patient with gallstone ileus who has been managed totally laparoscopically, detailing the technique and discussing the advantages of the laparoscopic approach with a review of the literature. METHODS The pneumoperitoneum was established with a Veress needle. A three-port approach (one 5-mm and two 10-mm trocars) and a 30° 10-mm laparoscope were used. The site of obstruction was 5 cm below the ligament of Treitz, and a single gallstone was identified. A 3-cm longitudinal enterotomy was created just above the site where the gallstone was located. An 8-cm-long gallstone was extracted. The enterotomy was closed transversely in a single layer of two sets of continuous sutures. RESULTS The procedure was safely performed with all the advantages of minimally invasive surgery. Previous studies often described laparoscopically assisted procedures for the treatment of gallstone ileus, using a small abdominal incision. In recent years, some reports have been published on the efficacy of the totally laparoscopic approach in the management of gallstone ileus. CONCLUSIONS Totally laparoscopic management of gallstone ileus could be safe and effective with suggested benefits for the elderly patients.


Case reports in oncological medicine | 2016

Diagnosis and Treatment of Mucinous Appendiceal Neoplasm Presented as Acute Appendicitis

Ioannis Kehagias; Apollon Zygomalas; Georgios Markopoulos; Thanasis Papandreou; Pantelis Kraniotis

Appendiceal mucocele is a rare cause of acute abdomen. Mucinous appendiceal neoplasms represent 0.2–0.7% of all appendix specimens. The aim of this study is to report a case of a mucinous appendiceal neoplasm presented as acute appendicitis, discussing the clinical and surgical approach in the emergency setting. A 72-year-old female patient was admitted to the emergency department with a clinical examination indicative of acute abdomen. The patient underwent abdominal computed tomography scan which revealed a cystic lesion in the right iliac fossa measuring 8.3 × 5.2 × 4.1 cm, with calcified walls, and a mean density indicative of high protein content. The patient was taken to the operating room and a right hemicolectomy was performed. The postoperative course was unremarkable. The histopathological examination revealed a low-grade mucinous appendiceal neoplasm with negative regional lymph nodes. Ultrasound and CT are useful in diagnosing appendiceal mucocele and synchronous cancers in the emergency setting. The initial operation should include appendectomy and resection of the appendicular mesenteric fat along with any fluid collection for cytologic examination. During urgent appendectomy it is important to consider every mucocele as malignant in order to avoid iatrogenic perforation causing pseudomyxoma peritonei. Although laparotomy is recommended, the laparoscopic approach is not contraindicated.


Minimally Invasive Surgery | 2014

In Silico Investigation of a Surgical Interface for Remote Control of Modular Miniature Robots in Minimally Invasive Surgery

Apollon Zygomalas; Konstantinos Giokas; Dimitrios D. Koutsouris

Aim. Modular mini-robots can be used in novel minimally invasive surgery techniques like natural orifice transluminal endoscopic surgery (NOTES) and laparoendoscopic single site (LESS) surgery. The control of these miniature assistants is complicated. The aim of this study is the in silico investigation of a remote controlling interface for modular miniature robots which can be used in minimally invasive surgery. Methods. The conceptual controlling system was developed, programmed, and simulated using professional robotics simulation software. Three different modes of control were programmed. The remote controlling surgical interface was virtually designed as a high scale representation of the respective modular mini-robot, therefore a modular controlling system itself. Results. With the proposed modular controlling system the user could easily identify the conformation of the modular mini-robot and adequately modify it as needed. The arrangement of each module was always known. The in silico investigation gave useful information regarding the controlling mode, the adequate speed of rearrangements, and the number of modules needed for efficient working tasks. Conclusions. The proposed conceptual model may promote the research and development of more sophisticated modular controlling systems. Modular surgical interfaces may improve the handling and the dexterity of modular miniature robots during minimally invasive procedures.


Archive | 2016

Performing Intraoperative Computer Assisted Risk Analysis for Oncologic Liver Surgery in Clinical Practice

Apollon Zygomalas; Dionissios Karavias; Dimitrios D. Koutsouris; Ioannis Maroulis; Dimitrios Karavias; Konstantinos Giokas; Vasileios Megalooikonomou

Oncologic liver surgery offers the only reasonable chance to cure liver cancer. Selection of patients is essential for effective treatment and in order to minimize perioperative complications. The hepatic surgeon has to achieve complete resection of the tumor(s) including devascularized liver segments and leave a sufficient future liver remnant volume (FLR). Computer assisted risk analysis can provide useful information regarding resectability, anatomical relations, risk areas and volumetric measurements. However, additional findings from the intraoperative ultrasound may modify the resection plan. The aim of this prospective study was to evaluate the intraoperative computer assisted risk analysis for oncologic liver surgery in clinical practice using a novel liver segmentation and surgery planning solution. Fourteen consecutive patients at our institution, undergoing elective major liver resections from August 2014 to July 2015 were enrolled in this prospective study. Additional intraoperative findings were incorporated on-site in the preoperative 3D models of five patients (35%). Mean intraoperative risk analysis time was 4.6min/case SD±0.9. Intraoperative virtual liver resections were designed in less than 2 minutes in all cases (mean 1.4min SD±0.4. The preoperative plan was finally changed in three patients (21%). Intraoperative computer assisted risk analysis provided rapid and reliable reevaluation of the preoperative plan and helped surgeons to select a safe approach for liver oncologic surgery.


Case reports in oncological medicine | 2016

Corrigendum to “Diagnosis and Treatment of Mucinous Appendiceal Neoplasm Presented as Acute Appendicitis”

Ioannis Kehagias; Apollon Zygomalas; Georgios Markopoulos; Thanasis Papandreou; Pantelis Kraniotis

[This corrects the article DOI: 10.1155/2016/2161952.].


Medical & Biological Engineering & Computing | 2016

Computer-assisted liver tumor surgery using a novel semiautomatic and a hybrid semiautomatic segmentation algorithm.

Apollon Zygomalas; Dionissios Karavias; Dimitrios D. Koutsouris; Ioannis Maroulis; Dimitrios Karavias; Konstantinos Giokas; Vasileios Megalooikonomou


International Journal of Reliable and Quality E-Healthcare archive | 2012

Modular Assembly Micro-Robots for Natural Orifice Transluminal Endoscopic Surgery, the Future of Minimal Invasive Surgery

Apollon Zygomalas; Kostas Giokas; Dimitris Koutsouris


Archive | 2018

Robotics in Surgical Techniques Robotics in Surgical Techniques: Present and Future Trends

Vassilia Costarides; Apollon Zygomalas; Kostas Giokas; Dimitris Koutsouris


Archive | 2017

Robotics in Surgical Techniques: Present and Future Trends

Vassilia Costarides; Apollon Zygomalas; Kostas Giokas; Dimitris Koutsouris

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Dimitrios D. Koutsouris

National Technical University of Athens

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Konstantinos Giokas

National Technical University of Athens

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Dimitris Koutsouris

National Technical University of Athens

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Kostas Giokas

National Technical University of Athens

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Vassilia Costarides

National Technical University of Athens

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