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Dive into the research topics where Arlene Gwon is active.

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Featured researches published by Arlene Gwon.


Eye & Contact Lens-science and Clinical Practice | 2016

Penetrating and Intrastromal Corneal Arcuate Incisions in Rabbit and Human Cadaver Eyes: Manual Diamond Blade and Femtosecond Laser-Created Incisions.

Brad Gray; Perry S. Binder; Ling C. Huang; James M. Hill; Mercedes Salvador-Silva; Arlene Gwon

Objectives: To compare morphologic differences between freehand diamond or femtosecond laser-assisted penetrating and intrastromal arcuate incisions. Methods: Freehand diamond blade, corneal arcuate incisions (180° apart, 60° arc lengths) and 150 kHz femtosecond laser (80% scheimpflug pachymetry depth corneal thickness) arcuate incisions were performed in rabbits. Intrastromal arcuate incisions (100 &mgr;m above Descemets membrane, 100 &mgr;m below epithelium) were performed in rabbit corneas (energy 1.2 &mgr;J, spot line separation 3 × 3 &mgr;m, 90° side cut angle). Eyes were examined by slit lamp and light microscopy up to 47 days post-procedure. Freehand diamond blade penetrating incisions, and femtosecond laser penetrating and intrastromal arcuate incisions (energy 1.8 &mgr;J, spot line separation 2 × 2 &mgr;m) were performed in cadaver eyes. Optical coherence tomography was performed immediately after surgery and the corneas were fixed for light scanning and transmission electron microscopy. Results: The rabbit model showed anterior stromal inflammation with epithelial hyperplasia in penetrating blade and laser penetrating wounds. The laser intrastromal and penetrating incisions showed localized constriction of the stromal layers of the cornea near the wound. In cadaver eyes, penetrating wound morphology was similar between blade and laser whereas intrastromal wounds did not affect the cornea above or below incisions. Conclusion: Penetrating femtosecond laser arcuate incisions have more predictable and controlled outcomes shown by less post-operative scarring than incisions performed with a diamond blade. Intrastromal incisions do not affect uncut corneal layers as demonstrated by histopathology. The femtosecond laser has significant advantages in its ability to make intrastromal incisions which are not achievable by traditional freehand or mechanical diamond blades.


Investigative Ophthalmology & Visual Science | 1993

Lens regeneration in New Zealand albino rabbits after endocapsular cataract extraction.

Arlene Gwon; L J Gruber; C Mantras; C Cunanan


Investigative Ophthalmology & Visual Science | 1990

A histologic study of lens regeneration in aphakic rabbits.

Arlene Gwon; L J Gruber; K E Mundwiler


Investigative Ophthalmology & Visual Science | 1992

Lens regeneration in juvenile and adult rabbits measured by image analysis.

Arlene Gwon; R L Jones; L J Gruber; C Mantras


Investigative Ophthalmology & Visual Science | 1993

Concanavalin A-induced posterior subcapsular cataract: a new model of cataractogenesis.

Arlene Gwon; C Mantras; L J Gruber; C Cunanan


Investigative Ophthalmology & Visual Science | 2012

Comparison of Postoperative Wound Healing Following Penetrating or Intrastromal Corneal Arcuate Incisions in Rabbit Eyes Performed with a Diamond Blade or Femtosecond Laser

Brad Gray; Ling C. Huang; James M. Hill; Mercedes Salvador-Silva; Arlene Gwon; Perry S. Binder; Michael Brownell


Investigative Ophthalmology & Visual Science | 2007

Lens Regeneration With an Injectable Polymeric Scaffold

Arlene Gwon; L. Gruber


Investigative Ophthalmology & Visual Science | 2015

Evaluation of a New Compact Phacoemulsification System for Extracapsular Lens Extraction during Cataract Surgery in a Rabbit Model

Ling C. Huang; Mercedes Salvador-Silva; Tim I. Hunter; Arlene Gwon


Investigative Ophthalmology & Visual Science | 2012

Pre-Clinical Evaluation of Femtosecond Laser-assisted Capsulotomy in Cataract Surgery

James E Hill; Ling C. Huang; Brad Gray; Patrick De Guzman; Arlene Gwon; Luis G. Vargas; Michael Brownell


Investigative Ophthalmology & Visual Science | 2012

Determining Femtosecond Laser Parameters for Clear Corneal Incisions

Roger F. Steinert; Perry S. Binder; Brad Gray; Zsolt Bor; Michael Brownell; Jaime Martiz; Arlene Gwon; James M. Hill; Luis G. Vargas

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L J Gruber

University of California

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C Mantras

University of California

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James M. Hill

Louisiana State University

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K E Mundwiler

University of California

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R L Jones

University of California

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