Arthur Stempel

ANTIMETABOLITES PRODUCED BY MICROORGANISMS. V1) L-2-AMINO-4-METHOXY-TRANS-3-BUTENOIC ACID

L-2-Amino-4-methoxy-trans-3-butenoic acid was isolated from a fermentation broth of Pseudomonas aeruginosa ATCC-7700. This substance inhibited the growth of Bacillus species 1283 B in a chemically defined medium. The growth inhibition was reversed by a variety of amino acids.

Gas-liquid chromatographic determination of antibiotic X-537A, lasalocid

Abstract A method is described for the chemical analysis of lasalocid, formerly known as antibiotic X-537A. The method is based on quantitative thermolysis of the antibiotic to a retroaldol ketone which is assayed by gas chromatography. No catalyst or special pyrolysis attachment is needed for the assay, as cleavage of the antibiotic is complete in the injection port of the gas chromatograph. This technique has the advantage that no derivatization step is necessary prior to analysis.

The structure determination of a novel C 17 metabolite from streptomyces X-537 using Eu (DPM) 3

Die Struktur destrans-6-[2-(1-hydroxybutyl)-4-tolyl]-hex-5-enamids (I), eines neuen mikrobiellen Metaboliten, wurde durch Protonenresonanz-Spektroskopie unter Verwendung des Verschiebungsreagenz Eu (DPM)3 bestimmt.