Arzu Canan

Artificial neural network-based classification system for lung nodules on computed tomography scans

Lung cancer is the most common type of cancer among various cancers with the highest mortality rate. The fact that nodules that form on the lungs are in different shapes such as round or spiral in some cases makes their detection difficult. Early diagnosis facilitates identification of treatment phases and increases success rates in treatment. In this study, a holistic Computer Aided Diagnosis (CAD) system has been developed by using Computed-Tomography (CT) images to ensure early diagnosis of lung cancer and differentiation between benign and malignant tumors. The designed CAD system provides segmentation of nodules on the lobes with neural networks model of Self-Organizing Maps (SOM) and ensures classification between benign and malignant nodules with the help of ANN (Artificial Neural Network). Performance values of 90.63% accuracy, 92.30% sensitivity and 89.47% specificity were acquired in the CAD system which utilized a total of 128 CT images obtained from 47 patients.

Multiple tendon xanthomas in patient with heterozygous familial hypercholesterolaemia: sonographic and MRI findings

Tendon xanthomas are a component of familial hypercholesterolaemia, which is a hereditary disease and characterised by elevated low-density lipo protein cholesterol plasma levels and premature coronary artery disease. Tendon xanthomas are diagnostic for heterozygous familial hypercholesterolaemia (HFH) and they mostly occur in Achilles tendon. Sonography and MRI are superior to clinical assessment and are useful in detecting tendon xanthomas. In this report, we present ultrasonographic and MRI findings of multiple tendon xanthomas in a case of HFH.