Asad Aslam Khan

Better Thyroid Cytopathology Reporting System May Increase the ClinicalManagement and Patients Outcome

Objective: The Bethesda System is better for Thyroid Cytopathology reporting and may increase the clinical management of Thyroid Disease. Study design: Analytical Cross sectional. Material and methods: A cross sectional study was conducted on 120 smears of thyroid swellings which were referred for fine needle aspiration to the Department of Pathology in 2011 and the Bethesda System for reporting Thyroid Cytopathology was followed in comparison to old conventional reporting system running from the last 30 years. Histopathology was used as a gold standard to compare the sensitivity of both systems. Three groups of Histopathologists were assigned three reporting systems without knowing the results of each other. The comparison was made in a meeting of 3 groups after histopathology biopsy reports were made available. Group A was assigned to report with the older system of thyroid aspiration with 7 categories, Group B reported with five classes of an older reporting system and Group C reported with the latest Bethesda Reporting System. Screening test was applied to compare the results. Results: When the results of these three systems were compared Bethesda adapted method was found to be more superior as compared to the others. Sensitivity of Group B and C is significantly high 0.051 as compared to group A (p=0.051 and 0.000)’ Sensitivity of Group C is also significantly high as compared to Group B (p=0.000). Specificity of Group B is not significant (0.326) as compared to group A. Specificity of group C is also significantly high as compared to Group A and Group B (p=0.009 and 0.002). Our findings are consistent with others who used the Bethesda Cytopathology Reporting System. Conclusions: Bethesda Cytopathology Reporting system can help with a better patient’s outcome due to proper clinical management of thyroid swellings and saves patients from unnecessary thyroid surgery.

The cost of mapping trachoma: Data from the Global Trachoma Mapping Project

Background The Global Trachoma Mapping Project (GTMP) was implemented with the aim of completing the baseline map of trachoma globally. Over 2.6 million people were examined in 1,546 districts across 29 countries between December 2012 and January 2016. The aim of the analysis was to estimate the unit cost and to identify the key cost drivers of trachoma prevalence surveys conducted as part of GTMP. Methodology and principal findings In-country and global support costs were obtained using GTMP financial records. In-country expenditure was analysed for 1,164 districts across 17 countries. The mean survey cost was

Clinical outcome of 23g Trans-Conjunctival pars plana vitrectomy: A prospective comparison of Phaco-Vitrectomy with only vitrectomy in phakic eyes

13,113 per district [median:

Analysis of orbital malignancies presenting in a Tertiary Care Hospital in Pakistan

11,675; IQR =

Novel strategy to diagnose and grade hepatocellular carcinoma

8,365-

Predictors for Severity of Dengue Infection during Early Days of Infection

14,618],

Prevalence of Amblyopia among Government Middle School Children in City Of Lahore, Pakistan

17,566 per evaluation unit [median:

MODIFIED SCLERAL BUCKLING WITH A NON-CONTACT WIDE ANGLE VIEWING SYSTEM AND A 25G CHANDELIER ENDOILLUMINTOR

15,839; IQR =

Serotype Distribution and Demographics of Dengue Patients in a Tertiary Hospital of Lahore, Pakistan during the 2011 Epidemic

10,773-

Prognostic significance of retinoblastoma gene mutation in retinoblastoma eye with respect to pathological risk factors

19,915],