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Dive into the research topics where Ashok Chandra is active.

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Featured researches published by Ashok Chandra.


Journal of Human Reproductive Sciences | 2013

Prevalence of hepatic steatosis in women with polycystic ovary syndrome

Ritu Karoli; Jalees Fatima; Ashok Chandra; Uma Gupta; Faraz-ul Islam; Gagandeep Singh

OBJECTIVE: Nonalcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) both are known to be associated with insulin resistance and metabolic syndrome (MS). The aim of the study was to determine the presence of NAFLD and associated factors of hepatic steatosis in women with PCOS. MATERIALS AND METHODS: A cross-sectional hospital based study of 54 women with PCOS and 55 healthy controls who were age and weight matched were included. Anthropometric parameters, biochemical and hormonal investigations were done in all the patients. Insulin resistance was calculated by Homeostasis model assessment (HOMA). Abdominal ultrasonography and biochemical tests were used to determine the presence of hepatic steatosis after excluding other causes liver disease. RESULTS: Women with PCOS had a higher prevalence of hepatic steatosis (67% vs 25%, P = 0.001) MS (35% vs. 7%, P < 0.01) and elevated transaminases (31% vs. 7%, P = 0.03) than controls. All patients with PCOS and controls with MS had presence of hepatic steatosis. Age, BMI, waist-hip ratio, HOMA-IR, HDL and PCOS diagnosis were the factors associated with presence of hepatic steatosis. CONCLUSION: NAFLD is commonly present in women with PCOS in combination with other metabolic derangements. Evaluation for liver disease should be considered at an earlier age in women with PCOS, particularly those who have an evidence of MS.


Journal of family medicine and primary care | 2012

Salmonella hepatitis: an uncommon complication of a common disease.

Ritu Karoli; Jalees Fatima; Ashok Chandra; Gagandeep Singh

Typhoid fever is a very common infectious disease of tropics, associated with high morbidity and mortality. Typhoid fever is often associated with hepatomegaly and mildly deranged liver functions; a clinical picture of acute hepatitis is a rare complication. We report a young patient who presented with fever and jaundice and was found to have acute hepatitis secondary to typhoid fever. Recognition of Salmonella hepatitis is of clinical importance as it can mimic acute viral hepatitis. Early institution of specific therapy can improve the prognosis in these patients. Typhoid fever is a very common infectious disease of tropics, associated with high morbidity and mortality. Typhoid fever is often associated with hepatomegaly and mildly deranged liver functions; a clinical picture of acute hepatitis is a rare complication. We report a young patient who presented with fever and jaundice and was found to have acute hepatitis secondary to typhoid fever. Recognition of Salmonella hepatitis is of clinical importance as it can mimic acute viral hepatitis. Early institution of specific therapy can improve the prognosis in these patients.


Indian Journal of Endocrinology and Metabolism | 2013

Levothyroxine replacement and Ramadan fasting.

Ritu Karoli; Jalees Fatima; Ashok Chandra; Punj Prakash Mishra

Primary hypothyroidism is a common endocrine diseases and in recent times with increased awareness of thyroid diseases among internists, gynecologists and primary care physicians the number of patients with thyroid dysfunction seems increasing. During Ramadan, often patients find it difficult to administer levothyroxine on empty stomach since they may not wake up so early, so in this article suggestion has been given to take it at bed time. We conducted a prospective observational study during this years holy month of Ramadan on patients enrolled from our thyroid clinic who had hypothyroidism and decided to undertake fasting. Our aim was to study the impact of bed time levothyroxine on TSH (thyroid stimulating hormone) levels.


Journal of Association of Physicians of India | 2011

Attitudinal determinants of fasting in type 2 diabetes mellitus patients during Ramadan.

Fatim J; Ritu Karoli; Ashok Chandra; Naqvi N


Journal of Association of Physicians of India | 2013

A study of cardio-metabolic risk profile in patients with psoriasis.

Ritu Karoli; Jalees Fatima; Shukla; Dhillon Ks; Khanduri S; Maini S; Ashok Chandra


Journal of Association of Physicians of India | 2015

Endothelial Dysfunction by Flow-Mediated Vasodilatation in Chronic Kidney Disease.

Shukla; Dey R; Ashok Chandra; Ritu Karoli; Khanduri S


Indian Journal of Medical Specialities | 2012

Polymerase chain reaction and adenosine deaminase activity in tuberculous ascites

Jalees Fatima; Ritu Karoli; Ashok Chandra; Pradyumn Singh; Kajal Kumud


Journal of Association of Physicians of India | 2011

An unusual presentation of Kartagener's syndrome.

Shukla; Jalees Fatima; Ritu Karoli; Ashok Chandra; Khanduri S


Journal of Association of Physicians of India | 2016

Study of association of sono-radiographically assessed visceral and subcutaneous abdominal fat with insulin resistance in patients with prediabetes.

Jalees Fatima; Ritu Karoli; Ashok Chandra; Jagirdar S


Journal of Association of Physicians of India | 2014

Hepatolenticular degeneration--is the term too narrow to explain Wilson's disease?

Jalees Fatima; Ritu Karoli; Zeba Siddiqui; Ashok Chandra; Vineet Jain

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