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Dive into the research topics where Ashok R. Amin is active.

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Featured researches published by Ashok R. Amin.


Archive | 1999

Nitric Oxide in Systemic Lupus Erythematosus

H. Michael Belmont; Ashok R. Amin; Steven B. Abramson

Recent studies have established that excessive nitric oxide (NO) is produced during the course of both the human and the MRL/lpr model of systemic lupus erythematosus (SLE) (1–6). Although the inhibition of NO synthesis improves outcome in the MRL/lpr mice, the role of NO in the pathogenesis of SLE is as yet undetermined. The biology of NO, produced by constitutive or induced enzymes in virtually all tissues, is likely to exert complex actions on both immunologic and inflammatory processes. This chapter reviews the data that indicate that NO might play an important role in SLE. There is an emphasis on the biological reactivity of NO as well as its effects on cells of inflammation and immunity. An understanding of the pleiotropic effects of NO could advance our understanding of the pathogenesis of SLE and possibly lead to novel therapeutic strategies.


Journal of Biological Chemistry | 2000

Reversal of Autocrine and Paracrine Effects of Interleukin 1 (IL-1) in Human Arthritis by Type II IL-1 Decoy Receptor POTENTIAL FOR PHARMACOLOGICAL INTERVENTION

Mukundan Attur; Mandar N. Dave; Christine Cipolletta; Pil Kang; Mary B. Goldring; Indravadan R. Patel; Steven B. Abramson; Ashok R. Amin


Archive | 1998

Method for inhibiting cyclooxygenase-2 and tumor necrosis factor alpha

Ashok R. Amin; Steven B. Abramson; Inoravadan V. Patel


Archive | 1999

Regulation of Nitric Oxide and Inflammatory Mediators in Human Osteoarthritis-Affected Cartilage: Implication for Pharmacological Intervention

Ashok R. Amin; Mukundan Attur; Steven B. Abramson


Archive | 1997

Method of using tetracycline compounds for inhibition of nitric oxide production

Ashok R. Amin; Steven B. Abramson; Lorne M. Golub; Nungavaram S. Ramamurthy; Thomas F Mcnamara; Robert A. Greenwald; Howard Trachtman


Archive | 2009

Methods of using F-spondin as a biomarker for cartilage degenerative conditions and bone diseases

Steven B. Abramson; Mukundan Attur; Ashok R. Amin; Glyn D. Palmer


Archive | 1995

Osteoarthritis-associated inducable isoform of nitric oxide synthetase

Ashok R. Amin; Steven B. Abramson


Archive | 2007

Methods of using f-spondin as a biomarker for cartilage degenerative conditions

Steven B. Abramson; Mukundan Attur; Ashok R. Amin; Glyn D. Palmer


Archive | 2013

COX-2-Mediated Prostaglandin E2 Modified Tetracyclines: Inhibition of A Novel Mechanism of Action of Chemically

Ashok R. Amin; Indravadan V. Patel; Steven A. Stuchin; N. Patel; Mukundan Attur; Mandar N. Dave


Archive | 1998

Nicht antibakterielle tetracycline zur behandlung der multiplen sklerose Non-antibacterial tetracycline for the treatment of multiple sclerosis

Ashok R. Amin; Steven B. Abramson

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Steven B. Abramson

Beth Israel Deaconess Medical Center

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Mukundan Attur

Beth Israel Deaconess Medical Center

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Howard Trachtman

Pennsylvania State University

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Lorne M. Golub

State University of New York System

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Nungavaram S. Ramamurthy

State University of New York System

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Robert A. Greenwald

Long Island Jewish Medical Center

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Mandar N. Dave

Beth Israel Deaconess Medical Center

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