Ashraf Abou-Elela

Outcome of Treatment of Anterior Vaginal Wall Prolapse and Stress Urinary Incontinence with Transobturator Tension-Free Vaginal Mesh (Prolift) and Concomitant Tension-Free Vaginal Tape-Obturator

Objective. It is to assess the feasibility, effectiveness, and safety of transobturator tension-free vaginal mesh (Prolift) and concomitant tension-free vaginal tape-obturator (TVT-O) system as a treatment of female anterior vaginal wall prolapse associated with stress urinary incontinence (SUI). Patients and Methods. Between December 2006 and July 2007, 20 patients with anterior genital prolapse and voiding dysfunction were treated with the transobturator tension-free vaginal mesh (Prolift) and concomitant tension-free vaginal tape-obturator (TVT-O). Sixteen patients had stress urinary incontinence and 4 patients were considered at risk for development of de novo stress incontinence after the prolapse is repaired. All patients underwent a complete urodynamic assessment. All the patients underwent pelvic examination 4–6 weeks after the operation, and anatomical and functional outcomes were recorded. Results. Twenty cystocoeles were repaired: 6 grade II, 12 grade III, and 2 grade IV. There were no vessel or bladder injuries. Eighteen patients had optimal anatomic results and 2 patients had persistent asymptomatic stage I prolapse. Conclusion. These preliminary results suggest that Prolift system offers a safe and effective treatment for female anterior vaginal wall prolapse. However, a long-term followup is necessary in order to support the good result maintenance.

Inverted ureteral nipple as antireflux technique in surgical management of bilharzial ureteral strictures.

OBJECTIVES To present our initial clinical experience with the technique of inverted nipple ureteroneocystostomy in patients with dilated bilharzial ureters. METHODS A total of 36 patients with obstructed dilated bilharzial ureters (56 ureters) underwent inverted nipple ureteroneocystotomy after resection of the obstructed segment. Postoperatively, the patients were invited for follow-up at 3 and 6 months and yearly thereafter. At the first follow-up, urinalysis and culture examinations, serum creatinine measurement, ultrasonography, intravenous urography, or computed tomography, and voiding cystourethrography were performed. The mean follow-up was 32 months (range 16-52). RESULTS Symptomatic and radiologic improvement occurred in all patients, except for 2, and was sustained in all cases throughout the follow-up period. No reflux was demonstrated on static or voiding cystography in any patients. Recurrent postoperative hydronephrosis occurred in 2 reimplants (3.5%) owing to obstruction at the ureterovesical anastomosis. An episode of acute pyelonephritis requiring hospitalization and treatment with intravenous antibiotics occurred in 1 patient within the fist 6 months postoperatively. Mild reflux was subsequently demonstrated on voiding cystography. CONCLUSIONS The new technique of inverted nipple ureteroneocystostomy is suitable for reimplantation of dilated bilharzial ureters. Additional studies with a larger number of patients and longer follow-up are necessary to confirm these results.

Modified extravesical ureteral reimplantation technique for kidney transplants

PurposeWe describe a modification and evaluate a technique of extravesical ureteral reimplantation for kidney transplant.Materials and methodsWe reviewed the records of 120 kidney transplant recipients who underwent ureteral reimplantation via a modified extravesical technique. Follow-up evaluation included renal ultrasonography. Because reflux is not routinely assessed in transplant cases, only symptomatic reflux was considered a complication and accessed with voiding cystourethrography (VCUG). The urological complications evaluated included urinary fistula, ureteral stenosis and symptomatic vesicoureteral reflux.ResultsThe modified extravesical technique produced a successful result in 93.4% of patients with no symptomatic reflux or anastomotic obstruction. Anastomotic complications included stenosis in four patients, prolonged leakage and fistula in three patients, and symptomatic vesicoureteral reflux in one patient. Other urologic complications included complicated hematuria in three patients, postoperative urosepsis in one patient, and ureteral stenosis caused by extrinsic compression in three patients due to lymphocele (two patients) and by adhesions (one patient).ConclusionsThe modified extravesical ureteral reimplantation is a reliable procedure with predictable results comparable to those of more-traditional techniques and proved to be efficient without increasing the incidence of urological or anastomotic complications. This modified technique offers two advantages; removal of the ureteral stent with the urethral catheter without the need for a postoperative cystoscopy and facilitation of postoperative endoscopic maneuvers if needed.

A Novel Antireflux Technique for Orthotopic Ileal Bladder Substitutes—Flat-Segment Technique: Preliminary Results

Objective. Although a large debate exists regarding the need for reflux prevention in ileal orthotopic neobladders, it is our policy to continue performing nonrefluxing ureteroileal anastomoses for our patients. An ideal uretero-ileal anastomosis must be simple, nonrefluxing, as well as non-obstructive. Here, we present a new antireflux mechanism for orthotopic ileal neobladders. Methods. 12 radical cystectomy patients for muscle invasive bladder cancer were candidates for orthotopic urinary diversion and underwent a non-refluxing uretero-ileal anastomosis using the flat-segment technique with a follow up of 6 to 18 months. Results. Preliminary results after the short-term followup showed that the success rate in reflux prevention was 92% and no cases of obstruction. The upper tracts were preserved or improved in all 12 patients. Operative time for neobladder creation ranged between 120–240 minutes, with a mean of 165 minutes (±36 minutes). No diversion-related complications. Conclusions. Based on our early data, we believe that the flat-segment uretero-ileal anastomosis technique for reflux prevention in orthotopic ileal bladder substitutes is simple, easy to learn and carries no additional morbidity to a standard refluxing uretero-ileal anastomosis, but has the advantage of effective reflux prevention. A longer follow-up period study with more patient numbers is ongoing.

Outcome and complications of laparoscopic nephrectomy in patients with previous renal surgery.

OBJECTIVE The aim of this study was to evaluate the technical difficulties, limitations, outcome, and complications of laparoscopic nephrectomy in patients with previous ipsilateral renal surgery. MATERIALS AND METHODS Eighteen patients with a history of epsilateral renal surgery underwent laparoscopic simple nephrectomy for benign renal disease at our center between November 2001 and March 2005. All patients were informed about the details of the laparoscopic procedure, and an informed consent was obtained that included the possibility of an emergency laparotomy. All procedures performed were carried out through a transperitoneal approach. A separate table with a laparotomy set was available in the room and ready for open conversion. RESULTS The procedure was completed in 13 patients. Excluding the cases converted to open surgery, the operative time ranged from 120 to 210 minutes, with a mean of 170 +/- 32.9. The intraoperative blood loss ranged from 30 to 400 cc, with a mean blood loss of 100. Complications included minor visceral injury (liver) in 1 patient, minor bleeding in 2, major bleeding (open conversion) in 1, technical failure (open conversion) in 4, postoperative bleeding (reexploration) in 1, and postoperative renal bed collection in 1. CONCLUSIONS Laparoscopic nephrectomy is an alternative to the open nephrectomy for the removal of nonfunctioning kidneys in benign diseases and results in less morbidity and a shorter hospital stay. A higher conversion to open and complication rate should be expected in patients with previous open or endoscopic renal surgery and postinflammatory conditions.

Evaluation of Augmentation Ureterocystoplasty and Renal Transplantation

Objective: Clinical and surgical results in renal transplanta-tion candidates with voiding dysfunction and end stage renal disease who underwent augmentation ureterocysto-plasty were assessed. Patients and Methods: Ten patients 6–32 years old with dilated ureters, voiding dysfunction and end stage renal disease that underwent renal transplanta-tion following bladder augmentation from 1995 to 2005 were analyzed. The etiology of bladder dysfunction was a combination of neurogenic and non-neurogenic bladder and vesicoureteral reflux in 4 patients, neurogenic bladder in 3 patients and posterior urethral valves in 3 patients. All cases were assessed by ultrasonography, voiding cystoure-thrography and urodynamic means. Results: The mean fol-low-up was 32 months (range 6–82 months). Previous uro-dynamic evaluation revealed a mean bladder capacity of 130 ml (range 60–150 ml) and a mean intravesical pressure of 55 cm H2O (range 40–100 cm H2O). The urodynamic study after augmentation and kidney transplantation showed a mean bladder capacity of 380 ml (range 290–450 ml) and a mean intravesical pressure of 26 cm H2O (20–32 cm H2O) in 8 patients. None of the grafts were lost and the mean serum creatinine was 1.75 mg/dl. The most common complication was asymptomatic urinary tract infection. Conclusion: Ure-terocystoplasty in candidates for a renal transplant with low capacity and poorly compliant bladders combines the ben-efits common to all enterocystoplasties without adding to complications or risks.