Asish Kr. Banerjee

Enantiospecific synthesis of 8-epipuupehedione from (R)-(−)-carvone

An enantiospecific synthesis of the antitumor marine sponge metabolite puupehedione (2a) and its C8-epimer 2b as their methylenedioxy derivatives 8a and 8b was achieved through concomitant O-allyl deprotection and electrocyclization of 20 derived from (−)-carvone.

Design and synthesis of mannose analogues as inhibitors of α-mannosidase

Abstract A series of N-, C- and S- mannopyranosyl derivatives (4,9-16) have been synthesised and their inhibitory activity tested towards jackbean α-mannosidase (EC 3.2.1.24). These compounds are of mechanistic and synthetic interest in the design of new α-mannosidase inhibitors.

Heteroaryl radicals. Part 1. Synthesis of linear pyridine-fused ring systems by endo-selective 2-pyridyl radical cyclizationsThis paper has been dedicated to Professor U. R. Ghatak on the occasion of his 70th birthday.

Bu3SnH-induced 2-pyridyl radicals, derived from the 2-bromopyridinyl-substituted methylenecyclohexane 4 and also the vinyl- and the allyl-cyclohexanols 5 and 6, undergo endo-selective cyclizations to give six-, seven- and eight-membered-ring annulated pyridines 7, 11 and 12.

Regiocontrolled synthesis of spiro furopyrone-cyclohexane ring systems : approach to the pyranoditerpene lygodinolide

Abstract The isomeric α- and γ-pyrones 8 and 9 have been synthesised through oxidative cyclisation of the intermediate 5 , prepared via Claisen condensation of a protected β-ketoester with lithio ethyl acetate.