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Featured researches published by Atl Ng.


Hong Kong Medical Journal | 2017

Pathological outcome for Chinese patients with low-risk prostate cancer eligible for active surveillance and undergoing radical prostatectomy: comparison of six different active surveillance protocols

Cf Tsang; Hlj Tsu; Tct Lai; Kw Wong; Shb Ho; Atl Ng; Wk Ma; Mk Yiu

INTRODUCTION Active surveillance is one of the therapeutic options for the management of patients with low-risk prostate cancer. This study compared the performance of six different active surveillance protocols for prostate cancer in the Chinese population. METHODS Patients who underwent radical prostatectomy for prostate cancer from January 1998 to December 2012 at a university teaching hospital in Hong Kong were reviewed. Six active surveillance protocols were applied to the cohort. Statistical analyses were performed to compare the probabilities of missing unfavourable pathological outcome. The sensitivity and specificity of each protocol in identifying low-risk disease were compared. RESULTS During the study period, 287 patients were included in the cohort. Depending on different active surveillance protocols used, extracapsular extension, seminal vesicle invasion, pathological T3 disease, and upgrading of Gleason score were present on final pathology in 3.3%-17.1%, 0%-3.3%, 3.3%-19.1%, and 20.6%-34.5% of the patients, respectively. The University of Toronto protocol had a higher rate of extracapsular extension at 17.1% and pathological T3 disease at 19.1% on final pathology than the more stringent protocols from John Hopkins (3.3% extracapsular extension, P=0.05 and 3.3% pathological T3 disease, P=0.03) and Prostate Cancer Research International: Active Surveillance (PRIAS; 8.0% pathological T3 disease, P=0.04). The Royal Marsden protocol had a higher rate of upgrading of Gleason score at 34.5% compared with the more stringent protocol of PRIAS at 20.6% (P=0.04). The specificities in identifying localised disease and low-risk histology among different active surveillance protocols were 59%-98% and 58%-94%, respectively. The John Hopkins active surveillance protocol had the highest specificity in both selecting localised disease (98%) and low-risk histology (94%). CONCLUSIONS Active surveillance protocols based on prostate-specific antigen and Gleason score alone or including Gleason score of 3+4 may miss high-risk disease and should be used cautiously. The John Hopkins and PRIAS protocols are highly specific in identifying localised disease and low-risk histology.


Archive | 2017

Elective nephron-sparing surgery for renal cell carcinoma: Trifecta outcomes in a university teaching hospital

Tf Wong; Cf Tsang; Ahg Wong; Tct Lai; Jkw Wong; Shb Ho; Atl Ng; Wk Ma; Hlj Tsu; Mk Yiu

Correlations among penile length, prostate size, testicular volume and PSA in Chinese men VHW YEUNG, ATO YU, TCT PUN, CH CHENG, MTY CHAN, PSK CHU and CW MAN Division of Urology, Department of Surgery, Tuen Mun Hospital, Hong Kong Objective: There are numerous studies on the correlation of penile length with different body parameters published worldwide, but none of these studies are based on Chinese men. In this study, we analyzed the correlations among penile length, prostate size, testicular volume and PSA in Chinese men. Patients and Methods: From April 1 to July 31, 2016, 120 patients were recruited into the study. Their flaccid and stretched penile lengths were measured from tip to base of penis. Ultrasound was used to calculate the testicular volume and prostate size. PSA would be also taken on the same day. Results: Two patients with suspected prostate cancer were excluded from the analysis. The average patient’s age was 66.9 years (Range: 47–88 years) with a mean PSA of 3.7 ng/mL (Range: 0.2– 12.7 ng/mL). The average flaccid penile length was 8.4 cm (SD: 2.1 cm) whereas the mean stretched penile length was 10.3 cm (SD: 2.3 cm). The mean testicular volume was 8.9 cm (SD: 3.4 cm). There were some positive correlations identified: prostate size and flaccid penile length (R = 0.376), prostate size and stretched penile length (R = 0.323), prostate size and PSA (R = 0.286). Conclusion: There were positive correlations between prostate size and penile length or PSA. Retrospective review of roboticassisted Vs laparoscopic radical nephroureterectomy – sharing of a simplified approach requiring No patient repositioning or robot redocking CY NG, CH IP, CF LI, Y CHIU, TY CHU and FK


Archive | 2017

Diagnostic value of prostate imaging - reporting and data system (PI-RADS) version 2 in the Chinese population: a correlation study with magnetic resonance imaging (MRI)/ultrasound (US) fusion targeted biopsy

Wk Ma; Ash Lai; Kc Lam; Lkc Yip; Shb Ho; Jkw Wong; Ckw Wong; Tct Lai; Cf Tsang; Atl Ng; Hlj Tsu; Mk Yiu

Correlations among penile length, prostate size, testicular volume and PSA in Chinese men VHW YEUNG, ATO YU, TCT PUN, CH CHENG, MTY CHAN, PSK CHU and CW MAN Division of Urology, Department of Surgery, Tuen Mun Hospital, Hong Kong Objective: There are numerous studies on the correlation of penile length with different body parameters published worldwide, but none of these studies are based on Chinese men. In this study, we analyzed the correlations among penile length, prostate size, testicular volume and PSA in Chinese men. Patients and Methods: From April 1 to July 31, 2016, 120 patients were recruited into the study. Their flaccid and stretched penile lengths were measured from tip to base of penis. Ultrasound was used to calculate the testicular volume and prostate size. PSA would be also taken on the same day. Results: Two patients with suspected prostate cancer were excluded from the analysis. The average patient’s age was 66.9 years (Range: 47–88 years) with a mean PSA of 3.7 ng/mL (Range: 0.2– 12.7 ng/mL). The average flaccid penile length was 8.4 cm (SD: 2.1 cm) whereas the mean stretched penile length was 10.3 cm (SD: 2.3 cm). The mean testicular volume was 8.9 cm (SD: 3.4 cm). There were some positive correlations identified: prostate size and flaccid penile length (R = 0.376), prostate size and stretched penile length (R = 0.323), prostate size and PSA (R = 0.286). Conclusion: There were positive correlations between prostate size and penile length or PSA. Retrospective review of roboticassisted Vs laparoscopic radical nephroureterectomy – sharing of a simplified approach requiring No patient repositioning or robot redocking CY NG, CH IP, CF LI, Y CHIU, TY CHU and FK


Archive | 2017

Epithelioid angiomyolipoma of the kidney: a case series with literature review

Tf Wong; Cf Tsang; Atl Ng; Hlj Tsu; Tct Lai; Ckw Wong; Shb Ho; Wk Ma; Zq Lu; Cs Lo; Gg Lo; Rk Lo; Mk Yiu

Correlations among penile length, prostate size, testicular volume and PSA in Chinese men VHW YEUNG, ATO YU, TCT PUN, CH CHENG, MTY CHAN, PSK CHU and CW MAN Division of Urology, Department of Surgery, Tuen Mun Hospital, Hong Kong Objective: There are numerous studies on the correlation of penile length with different body parameters published worldwide, but none of these studies are based on Chinese men. In this study, we analyzed the correlations among penile length, prostate size, testicular volume and PSA in Chinese men. Patients and Methods: From April 1 to July 31, 2016, 120 patients were recruited into the study. Their flaccid and stretched penile lengths were measured from tip to base of penis. Ultrasound was used to calculate the testicular volume and prostate size. PSA would be also taken on the same day. Results: Two patients with suspected prostate cancer were excluded from the analysis. The average patient’s age was 66.9 years (Range: 47–88 years) with a mean PSA of 3.7 ng/mL (Range: 0.2– 12.7 ng/mL). The average flaccid penile length was 8.4 cm (SD: 2.1 cm) whereas the mean stretched penile length was 10.3 cm (SD: 2.3 cm). The mean testicular volume was 8.9 cm (SD: 3.4 cm). There were some positive correlations identified: prostate size and flaccid penile length (R = 0.376), prostate size and stretched penile length (R = 0.323), prostate size and PSA (R = 0.286). Conclusion: There were positive correlations between prostate size and penile length or PSA. Retrospective review of roboticassisted Vs laparoscopic radical nephroureterectomy – sharing of a simplified approach requiring No patient repositioning or robot redocking CY NG, CH IP, CF LI, Y CHIU, TY CHU and FK


Archive | 2017

Magnetic resonance imaging (MRI)/ultrasound (US) fusion guided prostate biopsy with an elastic fusion platform: is it useful in the Chinese population?

Wk Ma; Shb Ho; Jkw Wong; Ash Lai; Kc Lam; Ckw Wong; Ys Chan; Lkc Yip; Tct Lai; Cf Tsang; Atl Ng; Hlj Tsu; Mk Yiu

Correlations among penile length, prostate size, testicular volume and PSA in Chinese men VHW YEUNG, ATO YU, TCT PUN, CH CHENG, MTY CHAN, PSK CHU and CW MAN Division of Urology, Department of Surgery, Tuen Mun Hospital, Hong Kong Objective: There are numerous studies on the correlation of penile length with different body parameters published worldwide, but none of these studies are based on Chinese men. In this study, we analyzed the correlations among penile length, prostate size, testicular volume and PSA in Chinese men. Patients and Methods: From April 1 to July 31, 2016, 120 patients were recruited into the study. Their flaccid and stretched penile lengths were measured from tip to base of penis. Ultrasound was used to calculate the testicular volume and prostate size. PSA would be also taken on the same day. Results: Two patients with suspected prostate cancer were excluded from the analysis. The average patient’s age was 66.9 years (Range: 47–88 years) with a mean PSA of 3.7 ng/mL (Range: 0.2– 12.7 ng/mL). The average flaccid penile length was 8.4 cm (SD: 2.1 cm) whereas the mean stretched penile length was 10.3 cm (SD: 2.3 cm). The mean testicular volume was 8.9 cm (SD: 3.4 cm). There were some positive correlations identified: prostate size and flaccid penile length (R = 0.376), prostate size and stretched penile length (R = 0.323), prostate size and PSA (R = 0.286). Conclusion: There were positive correlations between prostate size and penile length or PSA. Retrospective review of roboticassisted Vs laparoscopic radical nephroureterectomy – sharing of a simplified approach requiring No patient repositioning or robot redocking CY NG, CH IP, CF LI, Y CHIU, TY CHU and FK


Archive | 2017

Fifteen-year experience in radical nephrectomy with inferior vena cava tumor thrombectomy for patients with locally advanced and metastatic renal cell carcinoma

Jtl Ng; Shb Ho; Atl Ng; Wk Ma; Hlj Tsu; Mk Yiu

Correlations among penile length, prostate size, testicular volume and PSA in Chinese men VHW YEUNG, ATO YU, TCT PUN, CH CHENG, MTY CHAN, PSK CHU and CW MAN Division of Urology, Department of Surgery, Tuen Mun Hospital, Hong Kong Objective: There are numerous studies on the correlation of penile length with different body parameters published worldwide, but none of these studies are based on Chinese men. In this study, we analyzed the correlations among penile length, prostate size, testicular volume and PSA in Chinese men. Patients and Methods: From April 1 to July 31, 2016, 120 patients were recruited into the study. Their flaccid and stretched penile lengths were measured from tip to base of penis. Ultrasound was used to calculate the testicular volume and prostate size. PSA would be also taken on the same day. Results: Two patients with suspected prostate cancer were excluded from the analysis. The average patient’s age was 66.9 years (Range: 47–88 years) with a mean PSA of 3.7 ng/mL (Range: 0.2– 12.7 ng/mL). The average flaccid penile length was 8.4 cm (SD: 2.1 cm) whereas the mean stretched penile length was 10.3 cm (SD: 2.3 cm). The mean testicular volume was 8.9 cm (SD: 3.4 cm). There were some positive correlations identified: prostate size and flaccid penile length (R = 0.376), prostate size and stretched penile length (R = 0.323), prostate size and PSA (R = 0.286). Conclusion: There were positive correlations between prostate size and penile length or PSA. Retrospective review of roboticassisted Vs laparoscopic radical nephroureterectomy – sharing of a simplified approach requiring No patient repositioning or robot redocking CY NG, CH IP, CF LI, Y CHIU, TY CHU and FK


Archive | 2017

Computer tomography overestimates the actual tumor size of renal cell carcinoma

Ahg Wong; Cf Tsang; Tf Wong; Ckw Wong; Tct Lai; Jkw Wong; Shb Ho; Atl Ng; Wk Ma; Hlj Tsu; Mk Yiu

Correlations among penile length, prostate size, testicular volume and PSA in Chinese men VHW YEUNG, ATO YU, TCT PUN, CH CHENG, MTY CHAN, PSK CHU and CW MAN Division of Urology, Department of Surgery, Tuen Mun Hospital, Hong Kong Objective: There are numerous studies on the correlation of penile length with different body parameters published worldwide, but none of these studies are based on Chinese men. In this study, we analyzed the correlations among penile length, prostate size, testicular volume and PSA in Chinese men. Patients and Methods: From April 1 to July 31, 2016, 120 patients were recruited into the study. Their flaccid and stretched penile lengths were measured from tip to base of penis. Ultrasound was used to calculate the testicular volume and prostate size. PSA would be also taken on the same day. Results: Two patients with suspected prostate cancer were excluded from the analysis. The average patient’s age was 66.9 years (Range: 47–88 years) with a mean PSA of 3.7 ng/mL (Range: 0.2– 12.7 ng/mL). The average flaccid penile length was 8.4 cm (SD: 2.1 cm) whereas the mean stretched penile length was 10.3 cm (SD: 2.3 cm). The mean testicular volume was 8.9 cm (SD: 3.4 cm). There were some positive correlations identified: prostate size and flaccid penile length (R = 0.376), prostate size and stretched penile length (R = 0.323), prostate size and PSA (R = 0.286). Conclusion: There were positive correlations between prostate size and penile length or PSA. Retrospective review of roboticassisted Vs laparoscopic radical nephroureterectomy – sharing of a simplified approach requiring No patient repositioning or robot redocking CY NG, CH IP, CF LI, Y CHIU, TY CHU and FK


Archive | 2017

How accurate are transrectal ultrasound guided biopsy and magnetic resonance imaging in staging prostate cancer and will we advise the wrong patient for active surveillance? A retrospective review in Hong Kong

Ys Chan; Wk Ma; Cf Tsang; Tct Lai; Jkw Wong; Shb Ho; Atl Ng; Hlj Tsu; Mk Yiu

Correlations among penile length, prostate size, testicular volume and PSA in Chinese men VHW YEUNG, ATO YU, TCT PUN, CH CHENG, MTY CHAN, PSK CHU and CW MAN Division of Urology, Department of Surgery, Tuen Mun Hospital, Hong Kong Objective: There are numerous studies on the correlation of penile length with different body parameters published worldwide, but none of these studies are based on Chinese men. In this study, we analyzed the correlations among penile length, prostate size, testicular volume and PSA in Chinese men. Patients and Methods: From April 1 to July 31, 2016, 120 patients were recruited into the study. Their flaccid and stretched penile lengths were measured from tip to base of penis. Ultrasound was used to calculate the testicular volume and prostate size. PSA would be also taken on the same day. Results: Two patients with suspected prostate cancer were excluded from the analysis. The average patient’s age was 66.9 years (Range: 47–88 years) with a mean PSA of 3.7 ng/mL (Range: 0.2– 12.7 ng/mL). The average flaccid penile length was 8.4 cm (SD: 2.1 cm) whereas the mean stretched penile length was 10.3 cm (SD: 2.3 cm). The mean testicular volume was 8.9 cm (SD: 3.4 cm). There were some positive correlations identified: prostate size and flaccid penile length (R = 0.376), prostate size and stretched penile length (R = 0.323), prostate size and PSA (R = 0.286). Conclusion: There were positive correlations between prostate size and penile length or PSA. Retrospective review of roboticassisted Vs laparoscopic radical nephroureterectomy – sharing of a simplified approach requiring No patient repositioning or robot redocking CY NG, CH IP, CF LI, Y CHIU, TY CHU and FK


Archive | 2016

Magnetic resonance imaging/ultrasound fusion guided prostate biopsy detects more clinically significant prostate cancer than conventional systematic biopsy method

Wk Ma; Ckw Wong; Jkw Wong; Bsh Ho; Ys Chan; Ash Lai; Kc Lam; Lkc Yip; Atl Ng; Hlj Tsu; Mk Yiu

Aim: Our study aims to report the mid-term results of Venaseal (Medtronic) cyanoacrylate for treating incompetent great saphenous veins (GSV). Methods: Patients were followed up by serial clinical and duplex examinations at 1 week, 1,6,12,24 months. Venous clinical severity score (VCSS), Aberdeen varicose vein questionnaire (AVVQ), Short Form Health Survey 36 Item (SF36) questionnaires were used in conjunction. Cox regression analysis was used to examine pre-operative venous characteristics, such as incompetence at the saphenofemoral junction (SFJ), the diameter of GSV, treatment length of GSV, presence of incompetent perforators, pretreatment clinical severity of varicose vein, seniority of surgeon (consultants or fellows) as predictors of recanalisation. Results: One hundred and eight legs in 55 patients (21 male and 34 female, median age 65) with primary varicose veins were included. Our VCSS, AVVQ, and the SF36 physical and mental scores changed from a mean of 6.18, 25.38, 44.35, and 53.63 at baseline to 2.39, 7.87, 43.62, and 50.29 at 1 month post operation. Kaplen Meier analysis showed GSV closure rates were 97.2%, 92.3%, 89.2% and 75.7% at post-op 1 week, 1,6,12 months respectively. With median follow up period of 5 (range 0–18) months, 4 legs had clinical recurrence of varicosities. Mean GSV diameter >8 mm was the only significant predictor for recanalisation (Hazard ratio 7.2, 95%CI 2.4-21.5, p < 0.001). Conclusion: The procedure was safe, well tolerated, and durable in GSV less than 8 mm diameter, with a closure rate of 85.7% at 12 months. Majority of recanalisation was observed in GSVs with diameter >8 mm. EFP2


Archive | 2016

Minimizing renal ischemia in robot-assisted laparoscopic partial nephrectomy (RaLPN)

Tk Lo; Wk Ma; Bsh Ho; Atl Ng; Hlj Tsu; Mk Yiu

Abstract and Oral Presentation: Oral (Free Paper) Session III: Andrology / Stone & Infection / Stents: abstract no. OP.3-2

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Mk Yiu

University of Hong Kong

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Wk Ma

University of Hong Kong

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Kl Ho

Queen Mary Hospital

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Tm Chan

University of Hong Kong

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C-C Ng

University of Malaya

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