Atsuko Nishiguchi
Takeda Pharmaceutical Company
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Publication
Featured researches published by Atsuko Nishiguchi.
Tetrahedron | 2001
Tomomi Ikemoto; Atsuko Nishiguchi; Hiroyuki Mitsudera; Mitsuhiro Wakimasu; Kiminori Tomimatsu
Abstract A convenient and efficient synthesis of TAK-779 (1a), a nonpeptide CCR5 antagonist, has been achieved. The new methylation of tertiary amine (2) using trimethyl phosphite and N-chlorosuccinimide, followed by the addition of HCl led to ammonium chloride (1a) in 89% isolated yield without requiring a chromatographic method. By this preparation, ammonium methanesulfonate (1e) could be obtained in 75% isolated yield.
Synthesis | 2006
Atsuko Nishiguchi; Kazuhiro Maeda; Shokyo Miki
Tetrahedron Letters | 2004
Tomomi Ikemoto; Tatsuya Ito; Atsuko Nishiguchi; Kiminori Tomimatsu
Archive | 1999
Tomomi Ikemoto; Tadao Kawarazaki; Hideo Hashimoto; Kiminori Tomimatsu; Tatsuya Ito; Atsuko Nishiguchi
Organic Process Research & Development | 2005
Tomomi Ikemoto; Tatsuya Ito; Atsuko Nishiguchi; Syotaro Miura; Kiminori Tomimatsu
Organic Process Research & Development | 2000
Tomomi Ikemoto; Tatsuya Ito; Hideo Hashimoto; Tadao Kawarasaki; Atsuko Nishiguchi; Hiroyuki Mitsudera; and Mitsuhiro Wakimasu; Kiminori Tomimatsu
Archive | 2003
Hiroyuki Tawada; Tomomi Ikemoto; Atsuko Nishiguchi; Tatsuya Ito; Mari Adachi
Tetrahedron | 2004
Tomomi Ikemoto; Tatsuya Ito; Atsuko Nishiguchi; Kiminori Tomimatsu
Tetrahedron | 2005
Tomomi Ikemoto; Atsuko Nishiguchi; Tatsuya Ito; Hiroyuki Tawada
Archive | 2002
Hiroyuki Tawada; Makoto Yamashita; Tomomi Ikemoto; Atsuko Nishiguchi
