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Atsuyuki Kojima

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Publication

Featured researches published by Atsuyuki Kojima.

Bioorganic & Medicinal Chemistry Letters | 2010

Coumarins as novel 17β-hydroxysteroid dehydrogenase type 3 inhibitors for potential treatment of prostate cancer

Koichiro Harada; Hideki Kubo; Yoshitaka Tomigahara; Junya Takahashi; Mio Momose; Shin-ichi Inoue; Atsuyuki Kojima

The synthesis and SAR studies of 3- and 4-substituted 7-hydroxycoumarins as novel 17beta-HSD3 inhibitors are discussed. The most potent compounds from this series exhibited low nanomolar inhibitory activity with acceptable selectivity versus other 17beta-HSD isoenzymes and nuclear receptors.

Archive | 1986

Imide derivatives, their production and use

Kikuo Ishizumi; Fujio Antoku; Isamu Maruyama; Atsuyuki Kojima

Chemical & Pharmaceutical Bulletin | 1991

Synthesis and anxiolytic activity of N-substituted cyclic imides (1R*,2S*,3R*,4S*)-N-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,3- bicyclo[2.2.1]heptanedicarboximide (tandospirone) and related compounds.

Kikuo Ishizumi; Atsuyuki Kojima; Fujio Antoku

Archive | 1994

Indoloylguanidine derivatives as inhibitors of sodium-hydrogen exchange

Atsuyuki Kojima; Masahumi Kitano; Akira Miyagishi; Tsuyoshi Noguchi; Hideki Yagi; Kazuhiro Nakano; Naohito Ohashi

Archive | 1995

Novel lactam derivatives

Atsuyuki Kojima; Fujio Antoku; Mayumi Yoshigi; Norihiko Tanno; Toshio Nishihara; Tomohiro Toyoda; Yukihiro Ohno

Chemical & Pharmaceutical Bulletin | 1995

Succinimide Derivatives. II. Synthesis and Antipsychotic Activity of N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cis-cyclohexanedicarboximide (SM-9018) and Related Compounds.

Kikuo Ishizumi; Atsuyuki Kojima; Fujio Antoku; Ikutaro Saji; Mayumi Yoshigi

Archive | 1987

Imide derivatives and their use in the treatment psychosis

Fujio Antoku; Mayumi Yoshigi; Ikutaro Saji; Atsuyuki Kojima; Kukuo Ishizumi

Bioorganic & Medicinal Chemistry Letters | 2006

A novel class of sodium/calcium exchanger inhibitors: design, synthesis, and structure-activity relationships of 4-phenyl-3-(piperidin-4-yl)-3,4-dihydro-2(1H)-quinazolinone derivatives.

Hirohiko Hasegawa; Masami Muraoka; Kazuki Matsui; Atsuyuki Kojima

Archive | 1988

Succinimide derivatives, and their production and use

Kikuo Ishizumi; Fujio Antoku; Isamu Maruyama; Atsuyuki Kojima

Chemical & Pharmaceutical Bulletin | 1999

Synthesis and biological activity of N-(aminoiminomethyl)-1H-indole carboxamide derivatives as Na+/H+ exchanger inhibitors.

Masafumi Kitano; Atsuyuki Kojima; Kazuhiro Nakano; Akira Miyagishi; Tsuyoshi Noguchi; Naohito Ohashi

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Fujio Antoku

Sumitomo Chemical

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Kikuo Ishizumi

Sumitomo Chemical

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Isamu Maruyama

Sumitomo Chemical

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Naohito Ohashi

University of Tokyo

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Ikutaro Saji

Kyoto University

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Yukihiro Ohno

Osaka University of Pharmaceutical Sciences

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Hirohiko Hasegawa

Dainippon Sumitomo Pharma Co.

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Kazuki Matsui

Kyoto University

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Masami Muraoka

University of Tokyo

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Hideki Kubo

Sumitomo Chemical

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