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Expert Opinion on Drug Delivery | 2006

Pulsed drug delivery

Atul Devdatt Ayer; Felix Theeuwes; Patrick S. L. Wong

Modern drug delivery aims to develop drug delivery systems that are able to meet specific therapeutic requirements. Whereas sustained drug release aims to maintain a constant drug level within the body, pulsed drug delivery intends to release the drug rapidly within a short period of time, as a result of a biological or external trigger, after a specific lag time. This editorial highlights some of the recent advances in new concepts for pulsed drug delivery and proposes some future strategies.


Archive | 1976

Osmotic system having laminar arrangement for programming delivery of active agent

Felix Theeuwes; Atul Devdatt Ayer


Archive | 1978

Osmotic system with distribution zone for dispensing beneficial agent

Atul Devdatt Ayer; Felix Theeuwes


Archive | 1979

Process for manufacturing device with dispersion zone

Atul Devdatt Ayer; Felix Theeuwes


Archive | 1977

Therapeutic device for osmotically dosing at controlled rate

Atul Devdatt Ayer; Felix Theeuwes


Archive | 1975

Osmotic devices having composite walls

Felix Theeuwes; Atul Devdatt Ayer


Archive | 1991

Dosage Form for Time-Varying Patterns of Drug Delivery

Patrick S. L. Wong; Felix Theeuwes; Atul Devdatt Ayer; Anthony L Kuczynski


Archive | 1976

Laminated osmotic system for dispensing beneficial agent

Felix Theeuwes; Atul Devdatt Ayer


Archive | 2004

Controlled release formulations of opioid and nonopioid analgesics

Evangeline Cruz; Atul Devdatt Ayer; Brenda Pollock; Carmelita Garcia; Sherry Li; Alfredo M. Wong; Lawrence G. Hamel; Cheri Enders Klein; Yihong Qiu; Ye Huang


Archive | 1991

Dosage form indicated for the management of abnormal posture, tremor and involuntary movement

David Emil Edgren; Howard A. Carpenter; Gurdish Kaur Bhatti; Atul Devdatt Ayer

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