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Dive into the research topics where Augustin Hittinger is active.

Publication


Featured researches published by Augustin Hittinger.


Bioorganic & Medicinal Chemistry Letters | 2011

Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: Advantages in comparison with competitive inhibitors

Dominique Lesuisse; Jacques Mauger; Conception Nemecek; Sébastien Maignan; Janine Boiziau; Greg Harlow; Augustin Hittinger; Swen Ruf; Hartmut Strobel; Anil Nair; Kurt Ritter; Jean-Luc Malleron; Anne Dagallier; Youssef El-Ahmad; Jean-Pierre Guilloteau; Houlfa Guizani; Herve Bouchard; Corinne Venot

A new series of IGF-1R inhibitors related to hydantoins were identified from a lead originating from HTS. Their noncompetitive property as well as their slow binding characteristics provided a series of compounds with unique selectivity and excellent cellular activities.


Archive | 2001

Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and preparation thereof

Daniel Achard; Herve Bouchard; Jean Bouquerel; Bruno Filoche; Serge Grisoni; Augustin Hittinger; Michael Myers


Archive | 2001

Azetidine derivatives, preparation thereof and pharmaceutical compositions containing same

Daniel Achard; Herve Bouchard; Jean Bouquerel; Bruno Filoche; Serge Grisoni; Augustin Hittinger; Michael Myers


Archive | 2001

Pharmaceutical compositions containing 3-amino-azetidine derivatives, novel derivatives and preparation thereof

Daniel Achard; Herve Bouchard; Jean Bouquerel; Bruno Filoche; Serge Grisoni; Augustin Hittinger; Michael Myers


Archive | 1999

Azetidine derivatives, preparation and medicines containing them

Daniel Achard; Herve Bouchard; Jean Bouquerel; Marc Capet; Serge Grisoni; Jean-Luc Malleron; Serge Mignani; Augustin Hittinger


Archive | 2001

Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation

Daniel Achard; Herve Bouchard; Jean Bouquerel; Bruno Filoche; Serge Grisoni; Augustin Hittinger; Michael Myers


Archive | 2001

Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and their preparation

Daniel Achard; Herve Bouchard; Jean Bouquerel; Bruno Filoche; Serge Grisoni; Augustin Hittinger; Michael Myers


Archive | 2007

Cyclic Urea Derivatives, Preparation Thereof And Pharmaceutical Use Thereof As Kinase Inhibitors

Hartmut Strobel; Sven Ruf; Dominique Lesuisse; Conception Nemecek; Youssef El-Ahmad; Stefan Guessregen; Anne Lebrun; Kurt Ritter; Didier Benard; Augustin Hittinger; Herve Bouchard


Archive | 2001

AZETIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM

Daniel Achard; Herve Bouchard; Jean Bouquerel; Marc Capet; Serge Grisoni; Jean-Luc Malleron; Serge Mignani; Augustin Hittinger


Archive | 2001

Azetidine derivatives, their preparation and pharmaceutical compositions containing them

Daniel Achard; Herve Bouchard; Jean Bouquerel; Bruno Filoche; Serge Grisoni; Augustin Hittinger; Michael Myers

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