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Austen Pimm

Loughborough University

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Publication

Featured researches published by Austen Pimm.

Bioorganic & Medicinal Chemistry Letters | 2011

The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos).

David Cheshire; Anders Åberg; Gunilla Andersson; Glen Andrews; Haydn Beaton; Timothy Nicholas Birkinshaw; Nigel Boughton-Smith; Stephen Connolly; Tony R. Cook; Anne Cooper; Sally L. Cooper; David Loughborough Cox; John Dixon; Nigel Gensmantel; Peter Hamley; Richard Harrison; Paul Hartopp; Helena Käck; Paul D. Leeson; Timothy Jon Luker; Antonio Mete; Ian Millichip; David Nicholls; Austen Pimm; Steve St-Gallay; Alan V Wallace

By careful analysis of experimental X-ray ligand crystallographic protein data across several inhibitor series we have discovered a novel, potent and selective series of iNOS inhibitors exemplified by compound 8.

Journal of Medicinal Chemistry | 2007

Discovery of Potent and Selective Adamantane-Based Small-Molecule P2X7 Receptor Antagonists/Interleukin-1β Inhibitors

Mark Furber; Lilian Alcaraz; Janice Bent; Armin Beyerbach; Keith Bowers; Martin Braddock; Moya Caffrey; David Cladingboel; John Collington; David Keith Donald; Malbinder Fagura; Frank Ince; Elizabeth Kinchin; Celine Laurent; Mandy Lawson; Timothy Jon Luker; Michael Mortimore; Austen Pimm; Robert J. Riley; Nicola J. Roberts; Mark J. Robertson; Jill Theaker; Philip Thorne; Richard Weaver; Peter J. H. Webborn; Paul Willis

Archive | 2007

Novel Tricyclic Spiropiperidine Compounds, Their Synthesis and Their Uses as Modulators of Chemokine Receptor Activity

Barry Elkins; David Ennis; Tomas Eriksson; Scott Gibson; Eric Gu; Ian Hassall; Martin Hemmerling; Bo-Göran Josefsson; Svetlana Ivanova; Santosh Kavitake; S. Kumar; Vinod Kumar; Sidda Lingesha; Marguerite Mensonides-Harsema; Eric Merifield; John Mo; John Pavey; Austen Pimm; James Reuberson; Mike Rogers; Håkan Schulz; Per Strandberg; Wang Zhengyu; Martin Cooper

Archive | 2000

5,7-bicyclic amidine derivatives useful as nitric oxide synthase inhibitors

David Cheshire; Stephen Connolly; David Cox; Peter Hamley; Timothy Jon Luker; Antonio Mete; Austen Pimm; Michael J. Stocks

Archive | 2010

Disaccharin, difumaric acid, di-l-hydroxy-2-naphthoic acid and mono-benzoic acid salts of 4- (dimethylamin0)butyl 2- (4- ( (2-amino-4-methyl-6- (pentylamino) pyrimidin- 5 -yl) methyl) phenyl)acetate

Nicholas James Bennett; Thomas Mcinally; Austen Pimm; Stephen Thom; Yoshiaki Isobe

Archive | 2008

Novel Compounds 243

Scott Gibson; Barry Elkins; Mike Rogers; Ian Hassall; Hong Gu; Zhenyu Wang; Vinod Kumar; Synthana Suresh Kumar; Santosh Kavitake; Sidda Lingesha; Eric Merifield; David Ennis; John Pavey; Austen Pimm; James Reuberson; Bo-Göran Josefsson; Martin Hemmerling; Svetlana Ivanova; Marguerite Mensonides-Harsema; Håkan Schulz; John Mo; Tomas Eriksson; Per Strandberg

Archive | 2006

Thiazole derivatives, their process for their preparation and their use in therapy

Andrew Douglas Baxter; Mark Furber; Sarah King; Christopher Luckhurst; Ian Millichip; Austen Pimm; James Reuberson

Archive | 2001

Novel use of phenylheteroakylamine derivatives

David Cheshire; Stephen Connolly; David Cox; Peter Hamley; Antonio Mete; Austen Pimm

publisher | None

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author

Archive | 2012

?COMPUESTOS NOVEDOSOS DE IMIDAZOQUINOLINA, COMPOSICIONES QUE LOS CONTIENEN Y SU USO EN EL TRATAMIENTO DE ENFERMEDADES MEDIADAS POR TLR7?

Thomas Mcinally; Austen Pimm

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Mark Furber

AstraZeneca

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Timothy Jon Luker

Loughborough University

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Lilian Alcaraz

Loughborough University

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Thomas Mcinally

Fisons

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Moya Caffrey

Fisons

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Michael Mortimore

Loughborough University

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Paul Willis

Loughborough University

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Peter Hamley

Loughborough University

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David Cheshire

Loughborough University

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Philip Thorne

Loughborough University

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