Ayako Hattori

Cognitive function in Japanese elderly with type 2 diabetes mellitus

The current study was conducted to investigate the cognitive function in Japanese elderly with type 2 diabetes mellitus (DM). Participants included 69 diabetic and 27 nondiabetic subjects (60 to 85 years old). The cognitive functional tests conducted were the Mini-Mental State Examination (MMSE), Word Lists Recall (immediate, delayed), Digit Symbol Test (Wechsler Adult Intelligence Scale-Revised [WAIS-R]), and the Stroop Color Word Test. Hemoglobin A1c (HbA1c) was measured as the index of glycemic control, and information about recent hypoglycemic episodes was gathered by using questionnaires. Students t test showed that DM subjects had significantly lower scores in the MMSE (P<.01) and Digit Symbol Test (P<.05) than non-DM subjects. The scores of the Digit Symbol Test in diabetes subjects had a significant negative relationship with HbA1c (r=-.433; P<.001), and insulin-use had a significant relationship with the scores of the MMSE and Digit Symbol Test. Subjects in the DM group were further divided by insulin use. Comparison of insulin-treated DM subjects, non-insulin-treated DM subjects, and nondiabetic subjects by analysis of variance followed by Bonferronis post hoc test showed that insulin-treated DM subjects had significantly lower scores in the MMSE and Digit Symbol Tests than both non-insulin-treated DM subjects (P<.05) and nondiabetic subjects (P<.01). Our study suggests that Japanese elderly DM subjects, especially those with insulin treatment, have poor cognitive function.

Standardization of plasma brain natriuretic peptide concentrations in older japanese - relationship to latent renal dysfunction and ischemic heart disease

OBJECTIVES: To determine the contributors to elevating plasma brain natriuretic peptide (BNP) concentrations in older people with normal systolic function. To investigate the relationship between cyclic guanosine monophosphate (cGMP) and BNP in older people with and without ischemic heart disease (IHD).

Effect of death education on self-determination in medical treatment in university students

Background:  Young people have little opportunity to acquire knowledge about or to determine in advance their medical preferences regarding their own end‐of‐life situation, including diagnosis disclosure and/or organ donation. Therefore a 90 min university‐level death education lecture was presented, which was designed to allow students to examine their attitudes regarding medical autonomy and to prepare themselves to make realistic decisions.

Assessment of brain atrophy in elderly subjects with diabetes mellitus by computed tomography

Several studies have shown cognitive functional impairment in elderly subjects with diabetic mellitus (DM). However, there have been few studies on the image of the brain in DM subjects.

Current admission policies of long‐term care facilities in Japan

Background:  The rapidly aging society in Japan is putting demands on long‐term care facilities for the elderly who require care. In Europe and the USA, there is ongoing reform of elderly care services, but the establishment of system based on social insurance is still being explored in Japan.