Ayca Altinkaya

Chronic inflammatory demyelinating polyradiculoneuropathy associated intracranial hypertension

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an acquired immune-mediated demyelinating neuropathy. In this report, we detail the course of a 58-year-old male patient who had headache and double vision followed by progressive paresthesia and difficulty in walking. The patient had bilateral papilledema and mild leg weakness, absent ankle jerks and loss of sensation in distal parts of his lower and upper extremities. His electromyography (EMG) was concordant with CIDP and lumbar puncture revealed high opening pressure. The polyradiculoneuropathy as well as the papilledema and elevated cerebrospinal fluid (CSF) pressure improved under steroids. The improvement in intracranial hypertension (IHT) and papilledema under steroid treatment suggests that the IHT in this patient might be associated with CIDP.

Cognitive impairment in neurosyphilis: Alzheimer's disease-like pattern?

assessed, performance of both constructive and gestural praxias was impaired. Conclusions: The PCA and within it, the Biparietal syndrome, occurs with failures in the visuospatial abilities and apraxia and has been linked to AD in up to 100% in some reports confirmed by pathology. A great degree of heterogeneity in clinical presentations of AD exists and memory can be spared even into advanced stages of the disease. Probably because of these reports clinical criteria for AD have been modified and therefore, considering the possible emergence of disease-modifying drugs, awareness of this kind of atypical presentations is important, in order to make an early diagnosis and an adequate treatment.