Ayodele Omotoso

Giant simple hepatic cyst: a case report and review of relevant literature

BACKGROUND Giant cysts of the liver are uncommon. Symptoms are related primarily to the mass effect of the enlarging cyst. OBJECTIVE To highlight the challenges of management of giant simple hepatic cyst in a resource limited setting. CASE REPORT Presented is a 58-year-old seamstress with a 5-year history of an enlarging abdominal mass with easy satiety. Surgery revealed an exophytic giant simple hepatic cyst arising from liver segment IV that drained 4.6 litres of serous fluid. CONCLUSION Simple hepatic cyst can attain giant dimensions and should be considered in the differential diagnosis of intraabdominal masses.

Marjolin’s Ulcer: Mismanaged Chronic Cutaneous Ulcers

Background: In developing countries, chronic cutaneous ulcers, scars, and osteomyelitic sinuses are common lesions. Marjolin’s ulcer is a malignant tumour that may arise from any of the above lesions. It may be misdiagnosed for infection and mismanaged as such. Method: We evaluated the clinical histories, treatment, and outcomes of patients who presented to the University of Calabar Teaching Hospital, Calabar with histologic diagnosis of Marjolin’s ulcer from January 2010 to December 2012. Results: The seven patients were 4 males and 3 females whose ages ranged from 28-70 years (mean 45.7 years). Trauma was the leading cause of injury resulting in ulceration [road traffic injuries- 4(57%), burns-2(29%)] while the other patient suffered diabetic foot ulcer. All the injuries involved the limbs [upper-1(14%), lower -6(86%)]. The histologic diagnosis in all the patients was squamous cell carcinoma with a mean latency period of 16.3 years. Late presentation with advanced loco-regional disease precluded curative surgery with poor outcomes. Conclusion: Marjolin’s ulcer is preventable and areas of intervention have been highlighted. Educations concerning prevention, risk of chronic ulceration, early presentation, prompt and proper treatment is advocated for improved outcome.

Cervical Cancer and its Aetiology in Sub-saharan Africa: A Literature Review

Cervical cancer represents a huge burden of non-inf ect ous disease globally. It is the second commonest cancer in the female. There are over half a million deaths recorded every year as result of cervical cancer. The aetiological agent i mpl cated in this disease is the human Papillomavirus. The high-risk human papillomavirus has been mostly implicated. The commonest high-risk human papillomavirus implicated in cervical cancer worldwide is type 16 and 18. The viral infection of the uterine cervical epithelium initially causes the development of precancerous lesions referred to as cervical intrae pithelial lesions/squamous intraepithelial lesions which take many years to progress into canc er. The Papanicoulao smear test done for the screening of precancerous cervical lesions has been known to be effective in preventing the disease. The commonest types of cervical cancer are the cervical squamous cell carcinoma and

Sudden deaths in hotels following sexual intercourse at south eastern Nigeria from 2010 to 2013

Aim/Objectives: This is to determine the actual cause of deaths of guests that walked in-to lodge in hotels in south eastern part of Nigeria. Materials and Methods: A sectional study of all reported deaths in hotels in Abia state, South Eastern Nigeria was undertaken. A total of seven (7) bodies were reported within the period of 2010-2013. All victims affected were males with an age range of 45-58 years and a mean age of 48.9 years. A detailed autopsy of all bodies was done at different time when they inquest (from coroner) was served by the law enforcement as the results of autopsies/court sermons kept intact. Results: All the bodies were seen to have died of cardiovascular-related disorder despite the ploy of report on the youngest of all-35 years that was said to have died in the swimming pool; we found out that he was already dead by the time the body was recovered from the pool. Conclusion: This shows that sexual activity is associated with augmented adrenergic stimulation that increases sympathetic output which resulted in increased heart rate with ventricular ectopic/fibrillation thus resulting to myocardiac infarction.

Giant Solitary Intramuscular Cystic Plexiform Neurofibroma of the Thigh: A Case Report and Literature Review

Objective: To report a rare occurrence of giant, solitary, cystic, intramuscular plexiform neurofibroma in the thigh. Case Report: A 45-year-old architect presented with a 5-year history of painless, progressively enlarging soft tissue mass in the right thigh, which was diagnosed on histology as cystic plexiform neurofibroma after excision biopsy. Conclusion: A plexiform neurofibroma should be considered in the differentials of a solitary cystic mass in the thigh even in the absence of usual manifestations of Neurofibromatosis.

Exhumation-Abduction with Violent Death in South Eastern Nigeria from 2007-2011

Aims & Objectives: This is to determine the cause of death of victims abducted as to aid justice to the relatives/nation and assist the law enforcement agent to conclude their investigation. Material and Methods: Eight People were abducted, five of which were men and three were females (two middle aged women and a young girl of about 20 years a grand daughter) that was abducted alongside with the aged grand mother. Results: Five of the cases were in advanced stages of decomposition but we were able to find the cause of death to be multiple soft tissue and skeletal injuries consequent to gunshots. The rest three though fresh bodies were seen with impressions of strangulation on the neck,ankle and the wrist with single shots either at heart,chest or liver regions. Conclusion: This has assisted for a truce in mitigating of justice and end to the missing individuals.

Rheumatoid Arthritis Complicated With Systemic A5myloidosis Diagnosed At Autopsy: A Case Report.

.The aetiology RA is still unclear, accumulating evidences are clarifying the involvement of genetic and environmental factors in the disease, or the pathogenic mechanism of perpetuating proliferative synovitis 3and bone destruction .Presenting primarily as articular and bone disease, it is the extra articular presentation and complcations however that are responsible for most fatalities