Aysin Kokturk

Disease‐specific quality of life is associated with anxiety and depression in patients with acne

Objective  We aimed to evaluate the relationships between acne severity, anxiety, depression and disease‐specific quality of life in patients with acne.

The prevalence of pediculosis capitis in schoolchildren in Mersin, Turkey

Background  Pediculosis capitis is an endemic parasitosis affecting many countries of the world. The aim of this study was to investigate the incidence of head lice infestation in Mersin, Turkey.

Plasma reactive oxygen species activity and antioxidant potential levels in rosacea patients: correlation with seropositivity to Helicobacter pylori

Background  Recent studies have suggested that there might be an etiologic role for Helicobacter pylori (HP) in rosacea. HP is a Gram‐negative bacterium that colonizes the gastric mucosa, increases the generation of reactive oxygen species (ROS), and decreases plasma antioxidants such as ascorbic acid.

Celecoxib-induced photoallergic drug eruption.

Photoallergic dermatitis is caused by a photosensitizing substance plus sunlight exposure in a sensitized person. If the photosensitizer is delivered internally, it is called a photoallergic drug reaction. Celecoxib is a new generation non‐steroidal anti‐inflammatory drug and sulfonamide derivative. We report a photoallergic drug eruption associated with the introduction of celecoxib. To our knowledge, this is the first report of photoallergic drug reaction associated with celecoxib.

Clinical and Pathological Manifestations with Differential Diagnosis in Behçet's Disease

Behçets disease is a multisystemic inflammatory disease of unknown etiology which usually occurs as a trait of symptoms: aphthous stomatitis, genital ulcerations, and ocular disease. At the beginning of the disease the diagnosis is uncertain because of various clinical manifestations and a long period up to the full clinical picture manifestation. Since neither the laboratory data nor the histopathological signs are truly pathognomonic in Behçets disease, the differential diagnosis depends on a careful evaluation of the medical history and meticulous physical examination to detect concomitant systemic manifestations. Sometimes, some laboratory test may help establish the diagnosis. Subspecialty referral to ophthalmology, rheumatology, neurology, and gastroenterology should be considered when indicated.

A simple surgical technique for the treatment of steatocystoma multiplex

Abstract

The early erosive vesicular stage of lipoid proteinosis: clinical and histopathological features

SIR, A 40-year-old man reported the slow progressive appearance, during the previous 6 years, of pruritic erythematous lesions on the trunk, buttock, abdomen, axilla, genital area and forearm (Fig. 1a). Lesions consisted of follicular papules, comedones, milia and cysts. Lesional areas were alopecic (Fig. 1b), and diffuse alopecia was also present on the scalp and beard area, along with comedones and cysts. The patient reported severe skin dryness, especially in the involved areas. No impairment of salivary or lacrimary function was noted. Serological and haematological tests were all normal or negative. Because of the diffuse presence of cysts and comedones, a diagnosis of chloracne had been made in another institution; the clinical diagnosis was confirmed histologically by the presence of infundibular cysts and a granulomatous foreign body reaction to keratin scales. A further biopsy was performed: the most striking histological feature was a lymphocytic infiltrate involving eccrine glands and coils along with a characteristic epithelial hyperplasia (Figs 1c,d). This picture fits perfectly with that reported in the literature as being characteristic of syringolymphoid hyperplasia, also known as syringotropic mycosis fungoides or syringotropic cutaneous T-cell lymphoma (CTCL). The hair follicles were involved by the lymphocytic infiltrate in a manner similar to that of the eccrine glands. Follicles were surrounded by a dense lymphocytic infiltrate, with extensive exocytosis. Occasional Pautrier microabscesses were evident in the follicular sheath. This pattern is that of pilotropic mycosis fungoides, a form of folliculotropic CTCL. Many follicles were entirely trans-

A case of ochronosis: upper extremity involvement

Abstract. We present an ochronotic patient with spondylosis and upper extremity involvement. We also evaluated radiologic findings of joints that were involved and MRI features of the lumbar spine.

The eclipse naevus and cockade naevus: are they two of a kind?

of excessive fat deposits, and weight loss might also be beneficial. While the genes for congenital generalized lipodystrophy and familial partial lipodystrophy have recently been idendified, the pathogenesis of acquired partial lipodystrophy remains unknown. However, it has been associated with autoimmune diseases, in particular renal disease. Up to one-third develop mesangiocapillary (membranoproliferative) glomerulonephritis, typically years after the onset of the lipodystrophy. Complement anomalies have been implicated in its pathogenesis. Patients commonly have low complement C3 levels and circulating C3 nephritic factor, and in vitro studies have shown C3 nephritic factor to cause lysis of adipose tissue. Other reported associations include systemic lupus erythematosus, dermatomyositis, hypothyroidism and pernicious anaemia, coeliac disease and dermatitis herpetiformis, rheumatoid arthritis, temporal arteritis, leucocytoclastic vasculitis, Raynaud’s phenomenon and cutaneous vasculits, and POEMS syndrome. In most cases the partial lipodystrophy preceded the associated disorder by years. C3 nephritic factor was not detected in the majority of these cases, suggesting another factor responsible for the changes seen in patients with partial lipodystrophy.

Familial eruptive dermatofibromas in atopic dermatitis

Multiple eruptive dermatofibromas (MEDF) are rare and their aetiology is unknown. More than half of the patients with MEDF have underlying diseases, and more than 80% of the underlying diseases are immune mediated. Familial cases suggesting a genetic cause have also been reported. We report a case of familial eruptive dermatofibromas associated with atopic dermatitis, possibly caused by both hereditary factors and compromised immunity.