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European Journal of Nuclear Medicine and Molecular Imaging | 1988

Lung water measurements with Iodo-antipyrine

Robert Y.L. Chu; V Paul CarlileJr.; B. A. Gray; E.William Allen; Garo P. Basmadjian; Janet Myers

Abstract131I labeled iodo-antipyrine and 99mTc labeled erythrocytes were used to measure water content in lungs. These radioactive tracers were injected into 10 rabbits with normal lungs and 11 rabbits with injured lungs. Blood samples were drawn and the subjects were killed. The lungs were removed, weighed and homogenized. Samples of blood and lung homogenate were assayed for 131I and 99mTc. Samples were also weighed before and after drying to a constant weight at 70–75°C. Extravascular lung water was determined by the dual isotope technique and again by gravimetric analysis. The average ratio of the results from the 2 different methods is 1.03±0.15. The 2 methods were compared by regression analysis and the correlation coefficient was 0.92±0.09. Our investigation suggests the possibility of measurement of lung water with equilibrium distribution of iodo-antipyrine.


The New England Journal of Medicine | 1983

Evaluation of right-heart catheterization in the critically ill patient without acute myocardial infarction

A. F. Connors; D. R. McCaffree; B. A. Gray


The American review of respiratory disease | 1981

Effect of inspiratory flow rate on gas exchange during mechanical ventilation

A. F. Connors; D. R. McCaffree; B. A. Gray


Journal of Applied Physiology | 1984

Effect of edema and hemodynamic changes on extravascular thermal volume of the lung

B. A. Gray; R. C. Beckett; R. C. Allison; D. R. McCaffree; R. M. Smith; E. D. Sivak; P. V. Carlile


Journal of Applied Physiology | 1981

Role of pulmonary edema in the acute pulmonary response to sepsis

D. R. McCaffree; B. A. Gray; B. E. Pennock; Jacqueline J. Coalson; C. Bridges; F. B. Taylor; Robert M. Rogers


Journal of Applied Physiology | 1986

Relationship between CO and transit times for dye and thermal indicators in central circulation

P. V. Carlile; R. C. Beckett; B. A. Gray


Journal of Applied Physiology | 1981

Role of platelet serotonin in the canine pulmonary response to endotoxin

T. L. Murphy; R. C. Allison; I. M. Weisman; D. R. McCaffree; B. A. Gray


The New England Journal of Medicine | 1983

Right-Heart Catheterization in the Critically Ill Patient

Fredrick N. Hanson; Allen B. Weisse; David H. Spodick; Valentin Popa; John Merritt O'donnell; Alfred F. Connors; D. Robert Mccaffree; B. A. Gray


Journal of Applied Physiology | 1981

Effect of methysergide on the acute lung mechanics response to endotoxin.

R. C. Allison; T. L. Murphy; I. M. Weisman; D. R. McCaffree; B. A. Gray


Survey of Anesthesiology | 1982

Effect of Inspiratory Flow Rate on Gas Exchange during Mechanical Ventilation

A. F. Connors; D. R. McCaffree; B. A. Gray

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