B. Bonin

Longitudinal study of alexithymia and multiple sclerosis

The aim of this study was to investigate the course of alexithymia and its relation with anxiety and depression in patients with multiple sclerosis (MS), over a period of 5 years.

Styles d’attachement et soutien social perçu chez des femmes déprimées

Resume Cette etude s’inspire du modele de l’attachement et des travaux sur le support social pour mettre en evidence une relation entre vulnerabilite depressive, styles d’attachement et support social. Elle porte sur l’investigation des styles d’attachement actuels et de la qualite du soutien social percu chez 35 sujets deprimes hospitalises compares a 35 temoins ne presentant aucune pathologie. Chaque sujet participe, apres avoir donne son consentement, a une investigation psychologique approfondie comportant un entretien clinique enregistre et plusieurs echelles cliniques. L’etude ne presente ici que les reponses au questionnaire de Perception des relations (4) qui distingue quatre styles d’attachement (secure, detache, preoccupe et desorganise) et au questionnaire de Soutien social (SSQ6) (46) qui comprend deux dimensions : la disponibilite et la satisfaction sociales. Les resultats ont fait l’objet d’une analyse statistique comparative entre les deux groupes et correlationnelle entre les dimensions du soutien social et celles du style d’attachement. L’etude met en evidence une plus faible disponibilite percue du reseau social chez les deprimes, l’absence de relation intime actuelle avec autrui et l’absence de confidents, ce qui est a relier a un plus grand nombre de pertes vecues par le sujet deprime, en particulier des figures d’attachement (pere et mere). Par ailleurs, les sujets deprimes presentent davantage des styles d’attachement preoccupe et desorganise qui se caracterisent comme des modeles de soi negatif. La discussion porte sur la maniere de comprendre ces styles d’attachement : representent-ils la consequence de la pathologie depressive ou bien sont-ils le reflet d’un style relationnel plus ancien ?

Potential influence of Type A personality on plasma C-reactive protein levels in people with diabetes

AIM Type A personality, although classically known as a factor linked to increased vascular risk, has recently been associated with increased survival in patients with diabetes. As low-grade inflammation predicts a poor outcome, the present study explored the potential associations between Type A and plasma levels of C-reactive protein (CRP) in diabetes. METHODS Type A personality was assessed by the Bortner questionnaire in people with diabetes. The association between Type A and plasma CRP levels was examined by multivariable linear regression, and structural equation modelling (SEM) was performed to determine the impact of the major clinical, biological and psychological confounders. RESULTS The study included 626 participants with type 1 and type 2 diabetes from the Diabetes and Psychological Profile study. Multivariable analyses showed an independent inverse association between Type A score and CRP levels. The structural model adjusted for age, gender, diabetes type and duration, body mass index (BMI), smoking status, alcohol abuse, oral antidiabetic and statin treatments, HbA1c levels, lipids, perceived stress, anxiety and depression revealed significant associations between CRP and Type A (β=-0.135, 95% CI: -0.242, -0.028; P=0.014), BMI (β=0.194, 95% CI: 0.038, 0.350; P=0.015) and HDL cholesterol (β=-0.132, 95% CI: -0.245, -0.020; P=0.014). CONCLUSION Our present study data indicate that Type A personality is independently associated with lower CRP levels. This lower level of inflammation might explain the better clinical outcomes associated with Type A personality in patients with diabetes.

Type A personality is not associated with poor glycaemic control: Data from cross-sectional and longitudinal surveys of people with type 1 or type 2 diabetes

Diabetes & Metabolism - In Press.Proof corrected by the author Available online since lundi 8 aout 2016