B. M. Pichurko

Breathing Pattern Affects Respiratory Heat Loss but Not Bronchoconstrictor Response in Asthma

AbstractTo determine whether changes in breathing pattern alone affect respiratory heat loss (RHL) and the constrictor response to cold dry gas hyperpnea in asthmatic subjects, we performed the following 2 part study: first we measured RHL in 8 asthmatic and 8 normal subjects during controlled eucapnic hypernea while they breathed at inspiratory to expiratory ratios (I/E) of 1:3, 3:1, and 2:2, and we recorded postchallenge forced expiratory volume in 1 sec (FEV1) in the asthmatic group; we then performed the same measurements in 8 asthmatic and 8 normal subjects at fixed target minute ventilation

Assessment of Bronchoalveolar Cell and Mediator Response to Isocapnic Hyperpnea in Asthma

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Finite difference analysis of respiratory heat transfer

for tidal volumes of 0.2 × Forced vital capacity (FVC), 0.4 × FVC, and 0.6 × FVC by varying the target respiratory rate appropriately. Our results show that (1) increasing I/E ratio or tidal volume-frequency ratio (VT/f) at fixed

Localization of the site of the bronchoconstrictor effects of leukotriene C4 compared with that of histamine in asthmatic subjects

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Breathing pattern affects airway wall temperature during cold air hyperpnea in humans.

produced small but statistically significant increases (p<0.05) in overall heat loss per unit volume of respired gas