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Featured researches published by B. Madsen.


Obstetrics & Gynecology | 1999

Port-site recurrence after laparoscopic surgery for endometrial carcinoma.

Howard G. Muntz; Barbara A. Goff; B. Madsen; Joseph L. Yon

BACKGROUND Women with endometrial carcinoma are being treated with laparoscopic surgery, but the risk of port-site recurrences remains undefined. CASE A 58-year-old woman underwent laparoscopically assisted vaginal hysterectomy, bilateral salpingo-oophorectomy, and laparoscopic lymphadenectomy for endometrial cancer. Final surgical stage was IA, with grade 2 histology. Twenty-one months later, she developed a 5-cm recurrent tumor mass at a lateral laparoscopic port site. The mass was resected, and a restaging laparotomy performed, without evidence of other metastases. Radiation therapy was administered to the involved anterior abdominal wall. Two and one half years later, there is no evidence of recurrence. CONCLUSION An isolated laparoscopic port-site recurrence might be attributable to the initial laparoscopic management of an otherwise good-prognosis endometrial carcinoma.


International Journal of Radiation Oncology Biology Physics | 2003

Intrafractional stability of the prostate using a stereotactic radiotherapy technique

B. Madsen; R. Alex Hsi; Huong T. Pham; Joseph Presser; Laura Esagui; John M. Corman; L. Myers; Douglas L. Jones

Abstract Purpose To evaluate the stability of the prostate during stereotactic radiation therapy. Methods and materials Forty-seven patients underwent placement of three fiducial markers into the prostate as part of a pilot study of hypofractionated stereotactic radiotherapy. Portal images before and subsequent to 227 radiotherapy fractions were analyzed for prostate movement. Six patients also underwent localizing radiographs at 6-min intervals for 24 min. Relative motion of the bony landmarks and prostate markers was calculated. Results Analysis of portal images revealed the undirected average prostate movement of 2.0 mm (superior/inferior), 1.9 mm (anterior/posterior), and 1.4 mm (right/left) with maximum standard deviation (SD) of 2.0. Analysis of radiographs at 6-min intervals showed the greatest undirected average prostate motion between 0–6 min; 1.5 mm (superior/inferior), 1.4 mm (anterior/posterior), and 0.4 mm (right/left). Beyond 6 min, movements decreased to 0.4, 0.9, and 0.8 mm, respectively. Bony landmark motion was 0.9 mm (superior/inferior), 0.9 mm (anterior/posterior), and 0.4 mm (right/left) between 0–6 min. Beyond 6 min, motion decreased to less than 0.5 mm in any direction. Conclusions Stereotactic prostate radiotherapy, utilizing fiducial marker localization, resulted in average intrafractional prostate movement of 2.0 mm or less. Most patient and organ movement occurs early and a settling-in period is advisable before treatment.


Cancer Journal | 2002

Intrafractional Stability of the Prostate Using a Stereotactic Radiotherapy Technique: 10:43 AM (31)

Richard A. Hsi; B. Madsen; John W. Rieke; Christine M. Cha; Huong T. Pham; John M. Corman

PURPOSE To evaluate the stability of the prostate during stereotactic radiation therapy. MATERIALS AND METHODS Forty-seven patients underwent placement of three fiducial markers into the prostate as part of a pilot study of hypofractionated stereotactic radiotherapy. Portal images before and subsequent to 227 radiotherapy fractions were analyzed for prostate movement. Six patients also underwent localizing radiographs at 6-min intervals for 24 min. Relative motion of the bony landmarks and prostate markers was calculated. RESULTS Analysis of portal images revealed the undirected average prostate movement of 2.0 mm (superior/inferior), 1.9 mm (anterior/posterior), and 1.4 mm (right/left) with maximum standard deviation (SD) of 2.0. Analysis of radiographs at 6-min intervals showed the greatest undirected average prostate motion between 0-6 min; 1.5 mm (superior/inferior), 1.4 mm (anterior/posterior), and 0.4 mm (right/left). Beyond 6 min, movements decreased to 0.4, 0.9, and 0.8 mm, respectively. Bony landmark motion was 0.9 mm (superior/inferior), 0.9 mm (anterior/posterior), and 0.4 mm (right/left) between 0-6 min. Beyond 6 min, motion decreased to less than 0.5 mm in any direction. CONCLUSIONS Stereotactic prostate radiotherapy, utilizing fiducial marker localization, resulted in average intrafractional prostate movement of 2.0 mm or less. Most patient and organ movement occurs early and a settling-in period is advisable before treatment.


International Journal of Radiation Oncology Biology Physics | 2007

STEREOTACTIC HYPOFRACTIONATED ACCURATE RADIOTHERAPY OF THE PROSTATE (SHARP), 33.5 GY IN FIVE FRACTIONS FOR LOCALIZED DISEASE: FIRST CLINICAL TRIAL RESULTS

B. Madsen; R. Alex Hsi; Huong T. Pham; Jack F. Fowler; Laura Esagui; John M. Corman


International Journal of Radiation Oncology Biology Physics | 2010

Five-year Outcome of Stereotactic Hypofractionated Accurate Radiotherapy of the Prostate (SHARP) for Patients with Low-risk Prostate Cancer

Huong T. Pham; G. Song; K. Badiozamani; M. Yao; John M. Corman; R.A. Hsi; B. Madsen


International Journal of Radiation Oncology Biology Physics | 2004

Comparison of rectal dose volume histograms for definitive prostate radiotherapy among stereotactic radiotherapy, IMRT, and 3D-CRT techniques

B. Madsen; Huong T. Pham; R.A. Hsi; Joseph Presser; Laura Esagui; N. Collins; T. Lawrence; G. Song; K. Badiozamani; M. Hunter; E. Taylor


International Journal of Radiation Oncology Biology Physics | 2006

62 : Hypofractionated Stereotactic Radiotherapy, 33.5Gy in Five Fractions, for Low Risk Prostate Cancer; Clinical Results

B. Madsen; R.A. Hsi; Huong T. Pham; Jack F. Fowler; Laura Esagui; John M. Corman


International Journal of Radiation Oncology Biology Physics | 2001

Development of apparatus and phase I trial for stereotactic hypofractionated accurate radiotherapy of the prostate (SHARP)

B. Madsen; Douglas L. Jones; R.A. Hsi; C. Cha; John W. Rieke


International Journal of Radiation Oncology Biology Physics | 2000

Regarding Nay and Gupta, IJROBP 2000;46:507–513

Douglas L. Jones; B. Madsen


International Journal of Radiation Oncology Biology Physics | 2008

Evaluation of Interfraction and Intrafraction Prostate Motion during the Treatment of Prostate Cancer using the Calypso 4D Localization System

R.A. Hsi; F. Vali; H. Parsai; E. Garver; B. Madsen; Huong T. Pham; G. Song; K. Badiozamani; P. Cho

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Huong T. Pham

Virginia Mason Medical Center

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R.A. Hsi

Virginia Mason Medical Center

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G. Song

Virginia Mason Medical Center

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K. Badiozamani

Virginia Mason Medical Center

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Laura Esagui

Virginia Mason Medical Center

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John M. Corman

Virginia Mason Medical Center

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Joseph Presser

Virginia Mason Medical Center

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H. Parsai

Virginia Mason Medical Center

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Douglas L. Jones

University of Western Ontario

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E. Taylor

Virginia Mason Medical Center

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