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B.R. Baker

University at Buffalo

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Publication

Featured researches published by B.R. Baker.

Journal of Pharmaceutical Sciences | 1964

Factors in the Design of Active-Site-Directed Irreversible Inhibitors

B.R. Baker

Journal of Heterocyclic Chemistry | 1964

Analogs of tetrahydrofolic acid. XII. On the relative contribution by the 2-amino and 4-hydroxy groups of 2-amino-5-(3-anilinopropyl)-6-methyl-4-pyrimidinol to inhibition of folic reductase and thymidylate synthetase †‡

B.R. Baker; Beng-Thong Ho; Thomas Neilson

Journal of Pharmaceutical Sciences | 1965

Analogs of Tetrahydrofolic Acid XXIV: Further Observations on the Mode of Pyrimidyl Binding to Dihydrofolic Reductase and Thymidylate Synthetase by the 2-amino-5-(3-anilinopropyl)-6-methyl-4-pyrimidinol Type of Inhibitor

B.R. Baker; Daniel V. Santi

Journal of Pharmaceutical Sciences | 1965

Analogs of Tetrahydrofolic Acid XXVII: Hydrophobic Bonding to Dihydrofolic Reductase by 2-Amino-4,6-disubstituted-5-alkylpyrimidines and 1-Alkyl-4,6-diamino-1,2-dihydro-s-triazines

B.R. Baker; Beng-Thong Ho; Daniel V. Santi

Journal of Pharmaceutical Sciences | 1965

Analogs of tetrahydrofolic acid XXVIII. Mode of pyrimidine binding to dihydrofolic reductase ph profile studies

B.R. Baker; Johannes H. Jordaan

Journal of Pharmaceutical Sciences | 1965

Nonclassical antimetabolites XVIII. Simulation of 5′-phosphoribosyl binding II. ω-uracil alkanoic acids related to 2′-deoxyuridylate

B.R. Baker; Girish B. Chheda

Journal of Heterocyclic Chemistry | 1965

Analogs of tetrahydrofolic acid. XXIX. Hydrophobic bonding to dihydrofolic reductase. II. On the mode of phenyl binding of 1‐aryl‐4,6‐diamino‐1,2‐dihydro‐2,2‐dimethyl‐s‐triazines

B.R. Baker; Beng-Thong Ho

Journal of Heterocyclic Chemistry | 1965

Analogs of tetrahydrofolic acid. XXI. Synthesis of 6‐bromomethyl‐5‐(p‐chlorophenyl)‐2,4‐diaminopyrimidine and its evaluation as a dihydrofolic reductase inhibitor

B.R. Baker; Johannes H. Jordaan

Journal of Pharmaceutical Sciences | 1964

Differential Inhibition of Dihydrofolic Reductase from Different Species

B.R. Baker; Beng-Thong Ho

Journal of Heterocyclic Chemistry | 1964

Analogs of tetrahydrofolic acid. XIII. On the mode of binding of the anilino group of 2-amino-5-(3-anilinopropyl)-6-methyl-4-pyrimidinol to dihydrofolic reductase and thymidylate synthetase †‡

B.R. Baker; Beng-Thong Ho; Girish B. Chheda

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Beng-Thong Ho

University at Buffalo

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Johannes H. Jordaan

University at Buffalo

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Prafullchandra M. Tanna

University at Buffalo

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Daniel V. Santi

University at Buffalo

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Girish B. Chheda

University at Buffalo

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Graham D.F. Jackson

University at Buffalo

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R.P. Patel

University at Buffalo

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Prabodh I. Almaula

University at Buffalo

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C.E. Morreal

University at Buffalo

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H.S. Sachdev

University at Buffalo

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