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Dive into the research topics where B R de Costa is active.

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Featured researches published by B R de Costa.


Pharmacological Reviews | 1990

Sigma receptors: biology and function.

Walker Jm; Wayne D. Bowen; F O Walker; Rae R. Matsumoto; B R de Costa; Rice Kc


Journal of Pharmacology and Experimental Therapeutics | 1993

Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities.

D R Compton; Rice Kc; B R de Costa; R K Razdan; Lawrence S. Melvin; Johnson Mr; B R Martin


Journal of Pharmacology and Experimental Therapeutics | 1993

Convulsive effects of systemic administration of the delta opioid agonist BW373U86 in mice.

S. D. Comer; E. M. Hoenicke; A. I. Sable; R. W. Mcnutt; Kwen-Jen Chang; B R de Costa; Henry I. Mosberg; James H. Woods


Journal of Pharmacology and Experimental Therapeutics | 1994

GBR12909 attenuates cocaine-induced activation of mesolimbic dopamine neurons in the rat.

M H Baumann; George U. Char; B R de Costa; Rice Kc; Richard B. Rothman


Journal of Pharmacology and Experimental Therapeutics | 1993

Kappa opioid antagonist effects of systemically administered nor-binaltorphimine in a thermal antinociception assay in rhesus monkeys.

Eduardo R. Butelman; S. Stevens Negus; Y Ai; B R de Costa; James H. Woods


Journal of Pharmacology and Experimental Therapeutics | 1994

Studies of the biogenic amine transporters. IV. Demonstration of a multiplicity of binding sites in rat caudate membranes for the cocaine analog [125I]RTI-55.

Richard B. Rothman; J L Cadet; Hyacinth C. Akunne; M L Silverthorn; M H Baumann; F I Carroll; Rice Kc; B R de Costa; John S. Partilla; J B Wang


Journal of Pharmacology and Experimental Therapeutics | 1991

Selective antagonism by naltrindole of the antinociceptive effects of the delta opioid agonist cyclic[D-penicillamine2-D-penicillamine5]enkephalin in the rat.

Edward J. Drower; Awilda Stapelfeld; Michael F. Rafferty; B R de Costa; Rice Kc; Donna L. Hammond


Journal of Pharmacology and Experimental Therapeutics | 1990

Apparent affinity of opioid antagonists in morphine-treated rhesus monkeys discriminating between saline and naltrexone.

B R de Costa; A. E. Jacobson; K. C. Rice; James H. Woods


Journal of Pharmacology and Experimental Therapeutics | 1993

Discriminative stimulus effects of BW373U86: a nonpeptide ligand with selectivity for delta opioid receptors.

S. D. Comer; R. W. Mcnutt; K J Chang; B R de Costa; Henry I. Mosberg; James H. Woods


Journal of Pharmacology and Experimental Therapeutics | 1992

Characterization of the enantiomers of cis-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)cyclohexylamine (BD737 and BD738): novel compounds with high affinity, selectivity and biological efficacy at sigma receptors.

Wayne D. Bowen; Walker Jm; B R de Costa; R Wu; Tolentino Pj; D Finn; Richard B. Rothman; Rice Kc

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Richard B. Rothman

National Institute on Drug Abuse

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George U. Char

Addiction Research Center

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S. D. Comer

University of Michigan

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