B. S. Sreeja

Design and analysis of Bistable MEMS switch

The aim of this paper is to design and analyze a Bistable MEMS switch which consumes energy only during the state transition. That means, when the switch is at one of its stable state, either ON or OFF, there is no power consumption. Basically switch is a bistable system. There are several bistable mechanisms, among them buckling mechanism is chosen to attain bistability in the proposed Bistable MEMS switch. Buckling is a mode of failure generally resulting from structural instability due to compressive action on the structural member or element involved. Compared to other bistable mechanisms, buckling mechanism has better feasibility with MEMS fabrication process. The proposed switch design opted centrally - clamped parallel beam structure to achieve buckling mechanism in order to attain the bistability. V-beam actuators are used to provide the critical loading at the middle of the centrally-clamped parallel beam which results in the buckling of the beam. Geometries of the proposed Bistable MEMS switch and their simulation results are presented. The proposed device needs a critical loading of 0.246N and it has an energy consumption of nearly 15μJ.

Design of PDMS membrane for CTC separation

Circulating tumorcells(CTC) are the primary tumor cells which contains the key information about the cancer. These CTCs can be separated from the peripheral blood in microfluidics, where a PDMS(polydimethylsiloxane) membrane can be designed for CTC detection. The PDMS membrane is designed with cylindrical pores for the detection of Circulating TumorCells(CTC) from the peripheral blood samples. The membrane consisting of cylindrical pores of size 9μm and the distance between the pores are designed to be (15μm) are simulated and analysed for the separation of CTCs.

Separation of bio-particles in micro fluidic device

Conventionally separation of bio-particle from blood is a long term process. Different methods are involved in separation of bio-particles. Bio-particles like bacteria, WBC, RBC are separated in a micro fluidic device by using pillars and applying different types of fields. In this paper, different shapes of pillars are analysed for efficient separation of bio-particles without applying different types of field, which pays way for the development of bio-particle separation filter. The overall length of the channel is 1cm and the size of the pillars is 12×15×8 μm.

Design of a bio-filter for particle separation

Cell separation and the diagnosis is an important step in the medical or Biological areas of research. The cell separation can be done by various techniques. A design is built with an array of micro-pillars where the micro-pillars acts as a filters which is used for the separation of spherical and non-spherical particles without the use of any external fields. The micro-pillars are designed in I-shape rather than a conventional shapeto separate plasma from blood where the diameter and height of each pillar is 12μm and 15μm respectively and the distance between the pillars are 8μm at the middle and 2μm at the edges. This paper discuss about the design of filter for particles separation without applying any external fields, consuming lower bio samples and lesser processing timein biomedical application.