Baindu L. Bayon

SP1-MODULATING COMPOUNDS AS A NOVEL DRUG TARGET FOR ALZHEIMER'S DISEASE (AD)

ethnography being observation. Person centred principles were used to guide the research process as well as inclusionary consent method (Dewing 2007). Guided reflective practice was the cornerstone of the inquiry. Results: Care staff gained insight into the drivers behind resident’s interactions when observations were discussed and reflected upon. Residents were found to have more agency in influencing their direct environment than previously thought possible. Conclusions: The results indicate there is strong potential for PIECE-dem to be used by practitioners to gain understanding of how the person with advanced dementia is experiencing their care environment, exercising agency, and how they can be appropriately supported.

BACE1 Gene Regulation: A Novel Drug Target in Alzheimer’s Disease

and perspective provided by an experienced researcher and investigator involved in a recently completed disease modifying immunotherapy program. Conclusions: It is imperative that methodological issues be identified and appropriately addressed in order to enhance the probability of success as the field moves forward into the long term investigation of earlier therapeutic interventions. We cannot afford to repeat the mistakes of the past.