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Balan Chenera

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Publication

Featured researches published by Balan Chenera.

Bioorganic & Medicinal Chemistry Letters | 1993

Nonpeptide HIV protease inhibitors designed to replace a bound water

Balan Chenera; Renee L. DesJarlais; Joseph Alan Finkelstein; Drake S. Eggleston; Thomas D. Meek; Thaddeus A. Tomaszek; Geoffrey B. Dreyer

Abstract Cyclic nonpeptide molecules were designed and synthesized with the goal of displacing the conserved flap-associated water of HIV-1 protease. Several such molecules were competitive inhibitors with micromolar inhibition constants, and their structure-activity relationships were consistent with the design hypothesis.

Journal of Organic Chemistry | 1993

Total synthesis of (±)-calanolide A, a non-nucleoside inhibitor of HIV-1 reverse transcriptase

Balan Chenera; Michael Leo West; Joseph Alan Finkelstein; Geoffrey B. Dreyer

Biochemistry | 1993

A symmetric inhibitor binds HIV-1 protease asymmetrically

Geoffrey B. Dreyer; Jeffrey Charles Boehm; Balan Chenera; Renee L. DesJarlais; Anne M. Hassell; Thomas D. Meek; Thaddeus A. Tomaszek; Mitchell Lewis

Journal of Organic Chemistry | 1997

Simple Silyl Linker for the Solid Phase Organic Synthesis of Aryl- Containing Molecules

Kenneth A. Newlander; Balan Chenera; Daniel F. Veber; Nelson C. F. Yim; Michael L. Moore

Journal of Organic Chemistry | 1992

Synthetic approaches to the axane family of sesquiterpenoids. Total synthesis of (dl)-axamide-4, (dl)-axisonitrile-4, and (dl)-axisothiocyanate-4

Balan Chenera; Che Ping Chuang; David J. Hart; Chin Shan Lai

Archive | 1993

Coumarin derivatives as retroviral inhibitors

Ashok D. Patil; Robert Philip Hertzberg; Geoffrey B. Dreyer; Alan J. Freyer; Balan Chenera; Michael Leo West

Journal of Organic Chemistry | 1985

Observations regarding .delta.- and .epsilon.-cyano radical cyclizations

Balan Chenera; Che Ping Chuang; David J. Hart; Leh Yeh Hsu

Archive | 1992

Carbocyclic and heterocyclic hiv protease inhibitors

Balan Chenera; Jarlais Renee Louise Des; Geoffrey B. Dreyer

Archive | 2001

Novel mmp-2/mmp-9 inhibitors

Anne Romanic Arnold; Balan Chenera; Gerald R. Girard; Joseph Weinstock

Archive | 2001

Inhibiteurs des mmp-2/mmp-9

Anne Romanic Arnold; Balan Chenera; Gerald R. Girard; Joseph Weinstock

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Collaboration

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Alan J. Freyer

Pennsylvania State University

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David J. Hart

Ohio State University

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Ashok D. Patil

University of New Brunswick

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Gerald R. Girard

GlaxoSmithKline

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Michael L. Moore

GlaxoSmithKline

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Thomas D. Meek

GlaxoSmithKline

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Daniel F. Veber

Merck

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Drake S. Eggleston

GlaxoSmithKline

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Jeffrey Charles Boehm

GlaxoSmithKline

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Kenneth A. Newlander

GlaxoSmithKline

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