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Featured researches published by Barbara Artnik.


Diabetologia | 2008

Socioeconomic inequalities in diabetes mellitus across Europe at the beginning of the 21st century

Albert Espelt; Carme Borrell; Albert-Jan Roskam; Maica Rodríguez-Sanz; Irina Stirbu; Albert Dalmau-Bueno; Enrique Regidor; Matthias Bopp; Pekka Martikainen; Mall Leinsalu; Barbara Artnik; Jitka Rychtarikova; Ramune Kalediene; Dagmar Dzúrová; Johan P. Mackenbach; Anton E. Kunst

Aims/hypothesisThe aim of this study was to determine and quantify socioeconomic position (SEP) inequalities in diabetes mellitus in different areas of Europe, at the turn of the century, for men and women.MethodsWe analysed data from ten representative national health surveys and 13 mortality registers. For national health surveys the dependent variable was the presence of diabetes by self-report and for mortality registers it was death from diabetes. Educational level (SEP), age and sex were independent variables, and age-adjusted prevalence ratios (PRs) and risk ratios (RRs) were calculated.ResultsIn the overall study population, low SEP was related to a higher prevalence of diabetes, for example men who attained a level of education equivalent to lower secondary school or less had a PR of 1.6 (95% CI 1.4–1.9) compared with those who attained tertiary level education, whereas the corresponding value in women was 2.2 (95% CI 1.9–2.7). Moreover, in all countries, having a disadvantaged SEP is related to a higher rate of mortality from diabetes and a linear relationship is observed. Eastern European countries have higher relative inequalities in mortality by SEP. According to our data, the RR of dying from diabetes for women with low a SEP is 3.4 (95% CI 2.6–4.6), while in men it is 2.0 (95% CI 1.7–2.4).Conclusions/interpretationIn Europe, educational attainment and diabetes are inversely related, in terms of both morbidity and mortality rates. This underlines the importance of targeting interventions towards low SEP groups. Access and use of healthcare services by people with diabetes also need to be improved.


Journal of Epidemiology and Community Health | 2010

Educational inequalities in avoidable mortality in Europe

Irina Stirbu; Anton E. Kunst; Matthias Bopp; Mall Leinsalu; Enrique Regidor; Santiago Esnaola; Giuseppe Costa; Pekka Martikainen; Carme Borrell; P Deboosere; Ramune Kalediene; Jitka Rychtarikova; Barbara Artnik; Johan P. Mackenbach

Background The magnitude of educational inequalities in mortality avoidable by medical care in 16 European populations was compared, and the contribution of inequalities in avoidable mortality to educational inequalities in life expectancy in Europe was determined. Methods Mortality data were obtained for people aged 30–64 years. For each country, the association between level of education and avoidable mortality was measured with the use of regression-based inequality indexes. Life table analysis was used to calculate the contribution of avoidable causes of death to inequalities in life expectancy between lower and higher educated groups. Results Educational inequalities in avoidable mortality were present in all countries of Europe and in all types of avoidable causes of death. Especially large educational inequalities were found for infectious diseases and conditions that require acute care in all countries of Europe. Inequalities were larger in Central Eastern European (CEE) and Baltic countries, followed by Northern and Western European countries, and smallest in the Southern European regions. This geographic pattern was present in almost all types of avoidable causes of death. Avoidable mortality contributed between 11 and 24% to the inequalities in Partial Life Expectancy between higher and lower educated groups. Infectious diseases and cardiorespiratory conditions were the main contributors to this difference. Conclusions Inequalities in avoidable mortality were present in all European countries, but were especially pronounced in CEE and Baltic countries. These educational inequalities point to an important role for healthcare services in reducing inequalities in health.


British Journal of Cancer | 2008

Educational differences in cancer mortality among women and men: a gender pattern that differs across Europe

Gwenn Menvielle; Anton E. Kunst; Irina Stirbu; Bjørn Heine Strand; Carme Borrell; Enrique Regidor; Annette Leclerc; Santiago Esnaola; Matthias Bopp; Olle Lundberg; Barbara Artnik; Giuseppe Costa; Patrick Deboosere; Pekka Martikainen; Johan P. Mackenbach

We used longitudinal mortality data sets for the 1990s to compare socioeconomic inequalities in total cancer mortality between women and men aged 30–74 in 12 different European populations (Madrid, Basque region, Barcelona, Slovenia, Turin, Switzerland, France, Belgium, Denmark, Norway, Sweden, Finland) and to investigate which cancer sites explain the differences found. We measured socioeconomic status using educational level and computed relative indices of inequality (RII). We observed large variations within Europe for educational differences in total cancer mortality among men and women. Three patterns were observed: Denmark, Norway and Sweden (significant RII around 1.3–1.4 among both men and women); France, Switzerland, Belgium and Finland (significant RII around 1.7–1.8 among men and around 1.2 among women); Spanish populations, Slovenia and Turin (significant RII from 1.29 to 1.88 among men; no differences among women except in the Basque region, where RII is significantly lower than 1). Lung, upper aerodigestive tract and breast cancers explained most of the variations between gender and populations in the magnitude of inequalities in total cancer mortality. Given time trends in cancer mortality, the gap in the magnitude of socioeconomic inequalities in cancer mortality between gender and between European populations will probably decrease in the future.


BMJ | 2016

Changes in mortality inequalities over two decades: register based study of European countries

Johan P. Mackenbach; Ivana Kulhánová; Barbara Artnik; Matthias Bopp; Carme Borrell; Tom Clemens; Giuseppe Costa; Chris Dibben; Ramune Kalediene; Olle Lundberg; P Martikainen; Gwenn Menvielle; Olof Östergren; Remigijus Prochorskas; Maica Rodríguez-Sanz; Bjørn Heine Strand; Caspar W. N. Looman; Rianne de Gelder

Objective To determine whether government efforts in reducing inequalities in health in European countries have actually made a difference to mortality inequalities by socioeconomic group. Design Register based study. Data source Mortality data by level of education and occupational class in the period 1990-2010, usually collected in a census linked longitudinal study design. We compared changes in mortality between the lowest and highest socioeconomic groups, and calculated their effect on absolute and relative inequalities in mortality (measured as rate differences and rate ratios, respectively). Setting All European countries for which data on socioeconomic inequalities in mortality were available for the approximate period between years 1990 and 2010. These included Finland, Norway, Sweden, Scotland, England and Wales (data applied to both together), France, Switzerland, Spain (Barcelona), Italy (Turin), Slovenia, and Lithuania. Results Substantial mortality declines occurred in lower socioeconomic groups in most European countries covered by this study. Relative inequalities in mortality widened almost universally, because percentage declines were usually smaller in lower socioeconomic groups. However, as absolute declines were often smaller in higher socioeconomic groups, absolute inequalities narrowed by up to 35%, particularly among men. Narrowing was partly driven by ischaemic heart disease, smoking related causes, and causes amenable to medical intervention. Progress in reducing absolute inequalities was greatest in Spain (Barcelona), Scotland, England and Wales, and Italy (Turin), and absent in Finland and Norway. More detailed studies preferably using individual level data are necessary to identify the causes of these variations. Conclusions Over the past two decades, trends in inequalities in mortality have been more favourable in most European countries than is commonly assumed. Absolute inequalities have decreased in several countries, probably more as a side effect of population wide behavioural changes and improvements in prevention and treatment, than as an effect of policies explicitly aimed at reducing health inequalities.


BMC Public Health | 2012

Socioeconomic inequalities in mortality from conditions amenable to medical interventions: do they reflect inequalities in access or quality of health care?

Iris Plug; Rasmus Hoffmann; Barbara Artnik; Matthias Bopp; Carme Borrell; Giuseppe Costa; Patrick Deboosere; Santi Esnaola; Ramune Kalediene; Mall Leinsalu; Olle Lundberg; Pekka Martikainen; Enrique Regidor; Jitka Rychtarikova; Bjørn Heine Strand; Bogdan Wojtyniak; Johan P. Mackenbach

BackgroundPrevious studies have reported large socioeconomic inequalities in mortality from conditions amenable to medical intervention, but it is unclear whether these can be attributed to inequalities in access or quality of health care, or to confounding influences such as inequalities in background risk of diseases. We therefore studied whether inequalities in mortality from conditions amenable to medical intervention vary between countries in patterns which differ from those observed for other (non-amenable) causes of death. More specifically, we hypothesized that, as compared to non-amenable causes, inequalities in mortality from amenable causes are more strongly associated with inequalities in health care use and less strongly with inequalities in common risk factors for disease such as smoking.MethodsCause-specific mortality data for people aged 30–74 years were obtained for 14 countries, and were analysed by calculating age-standardized mortality rates and relative risks comparing a lower with a higher educational group. Survey data on health care use and behavioural risk factors for people aged 30–74 years were obtained for 12 countries, and were analysed by calculating age-and sex-adjusted odds ratios comparing a low with a higher educational group. Patterns of association were explored by calculating correlation coefficients.ResultsIn most countries and for most amenable causes of death substantial inequalities in mortality were observed, but inequalities in mortality from amenable causes did not vary between countries in patterns that are different from those seen for inequalities in non-amenable mortality. As compared to non-amenable causes, inequalities in mortality from amenable causes are not more strongly associated with inequalities in health care use. Inequalities in mortality from amenable causes are also not less strongly associated with common risk factors such as smoking.ConclusionsWe did not find evidence that inequalities in mortality from amenable conditions are related to inequalities in access or quality of health care. Further research is needed to find the causes of socio-economic inequalities in mortality from amenable conditions, and caution should be exercised in interpreting these inequalities as indicating health care deficiencies.


Population Health Metrics | 2012

The contribution of educational inequalities to lifespan variation

Alyson A. van Raalte; Anton E. Kunst; Olle Lundberg; Mall Leinsalu; Pekka Martikainen; Barbara Artnik; Patrick Deboosere; Irina Stirbu; Bogdan Wojtyniak; Johan P. Mackenbach

BackgroundStudies of socioeconomic inequalities in mortality consistently point to higher death rates in lower socioeconomic groups. Yet how these between-group differences relate to the total variation in mortality risk between individuals is unknown.MethodsWe used data assembled and harmonized as part of the Eurothine project, which includes census-based mortality data from 11 European countries. We matched this to national data from the Human Mortality Database and constructed life tables by gender and educational level. We measured variation in age at death using Theils entropy index, and decomposed this measure into its between- and within-group components.ResultsThe least-educated groups lived between three and 15 years fewer than the highest-educated groups, the latter having a more similar age at death in all countries. Differences between educational groups contributed between 0.6% and 2.7% to total variation in age at death between individuals in Western European countries and between 1.2% and 10.9% in Central and Eastern European countries. Variation in age at death is larger and differs more between countries among the least-educated groups.ConclusionsAt the individual level, many known and unknown factors are causing enormous variation in age at death, socioeconomic position being only one of them. Reducing variations in age at death among less-educated people by providing protection to the vulnerable may help to reduce inequalities in mortality between socioeconomic groups.


Tobacco Control | 2017

Contribution of smoking to socioeconomic inequalities in mortality: a study of 14 European countries, 1990–2004

G Gregoraci; F.J. van Lenthe; Barbara Artnik; Matthias Bopp; P Deboosere; Katalin Kovács; Cwn Looman; Pekka Martikainen; Gwenn Menvielle; F Peters; Bogdan Wojtyniak; R de Gelder; J. P. Mackenbach

Background Smoking contributes to socioeconomic inequalities in mortality, but the extent to which this contribution has changed over time and driven widening or narrowing inequalities in total mortality remains unknown. We studied socioeconomic inequalities in smoking-attributable mortality and their contribution to inequalities in total mortality in 1990–1994 and 2000–2004 in 14 European countries. Methods We collected, harmonised and standardised population-wide data on all-cause and lung-cancer mortality by age, gender, educational and occupational level in 14 European populations in 1990–1994 and 2000–2004. Smoking-attributable mortality was indirectly estimated using the Preston-Glei-Wilmoth method. Results In 2000–2004, smoking-attributable mortality was higher in lower socioeconomic groups in all countries among men, and in all countries except Spain, Italy and Slovenia, among women, and the contribution of smoking to socioeconomic inequalities in mortality varied between 19% and 55% among men, and between −1% and 56% among women. Since 1990–1994, absolute inequalities in smoking-attributable mortality and the contribution of smoking to inequalities in total mortality have decreased in most countries among men, but increased among women. Conclusions In many European countries, smoking has become less important as a determinant of socioeconomic inequalities in mortality among men, but not among women. Inequalities in smoking remain one of the most important entry points for reducing inequalities in mortality.


Materia Socio Medica | 2016

FLUORIDE: A REVIEW OF USE AND EFFECTS ON HEALTH.

Domen Kanduti; Petra Šterbenk; Barbara Artnik

Introduction: Appropriate oral health care is fundamental for any individual’s health. Dental caries is still one of the major public health problems. The most effective way of caries prevention is the use of fluoride. Aim: The aim of our research was to review the literature about fluoride toxicity and to inform physicians, dentists and public health specialists whether fluoride use is expedient and safe. Methods: Data we used in our review were systematically searched and collected from web pages and documents published from different international institutions. Results: Fluoride occurs naturally in our environment but we consume it in small amounts. Exposure can occur through dietary intake, respiration and fluoride supplements. The most important factor for fluoride presence in alimentation is fluoridated water. Methods, which led to greater fluoride exposure and lowered caries prevalence, are considered to be one of the greatest accomplishments in the 20th century`s public dental health. During pregnancy, the placenta acts as a barrier. The fluoride, therefore, crosses the placenta in low concentrations. Fluoride can be transmitted through the plasma into the mother’s milk; however, the concentration is low. The most important action of fluoride is topical, when it is present in the saliva in the appropriate concentration. The most important effect of fluoride on caries incidence is through its role in the process of remineralization and demineralization of tooth enamel. Acute toxicity can occur after ingesting one or more doses of fluoride over a short time period which then leads to poisoning. Today, poisoning is mainly due to unsupervised ingestion of products for dental and oral hygiene and over-fluoridated water. Conclusion: Even though fluoride can be toxic in extremely high concentrations, it`s topical use is safe. The European Academy of Paediatric Dentistry (EAPD) recommends a preventive topical use of fluoride supplements because of their cariostatic effect.


International Journal of Public Health | 2008

Population groups at high risk for poor oral self care: the basis for oral health promotion

Barbara Artnik; Marjan Premik; Lijana Zaletel-Kragelj

SummaryObjectives:Identification of population groups at high risk for poor oral self-care in adults was needed in order to enable more focused planning of oral health promotion actions in Slovenia.Methods:The study was based on the national health behaviour database in adults aged 25-64. Data collected in 2001 were used. The sample size was 15,379. The overall response rate was 64 %, and 8,392 questionnaires were eligible for oral self-care assessment. A complex indicator based on oral hygiene, frequency of visiting a dentist, and nutritional habits was derived. The outcome of interest was poor oral self-care. Logistic regression was used to test multivariate associations between several factors (gender, age, educational level, social class, etc.) and poor oral self-care.Results:The overall prevalence of poor oral self-care was 6.9 %. The odds for this outcome were higher for men (ORmales vs. females = 7.49, p < 0.001), (or participants with the lowest educational levels (ORuncompleted primary vs. university = 5.95, p < 0.001; ORprimary vs. university = 4.95, p < 0.001), and for participants from the lowest social classes (ORlower vs. upper-middle = 6.20, p < 0.001; ORlabour vs. upper-middle = 4.05, p = 0.001).Conclusions:Special attention should be paid to oral health promotion for men, for those with low educational level, and for those belonging to the lowest social classes.


Health Affairs | 2017

Trends In Inequalities In Mortality Amenable To Health Care In 17 European Countries

Johan P. Mackenbach; Yannan Hu; Barbara Artnik; Matthias Bopp; Giuseppe Costa; Ramune Kalediene; Pekka Martikainen; Gwenn Menvielle; Bjørn Heine Strand; Bogdan Wojtyniak; Wilma Nusselder

Little is known about the effectiveness of health care in reducing inequalities in health. We assessed trends in inequalities in mortality from conditions amenable to health care in seventeen European countries in the period 1980-2010 and used models that included country fixed effects to study the determinants of these trends. Our findings show remarkable declines over the study period in amenable mortality among people with a low level of education. We also found stable absolute inequalities in amenable mortality over time between people with low and high levels of education, but widening relative inequalities. Higher health care expenditure was associated with lower mortality from amenable causes, but not from nonamenable causes. The effect of health care expenditure on amenable mortality was equally strong, in relative terms, among people with low levels of education and those with high levels. As a result, higher health care expenditure was associated with a narrowing of absolute inequalities in amenable mortality. Our findings suggest that in the European context, more generous health care funding provides some protection against inequalities in amenable mortality.

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Johan P. Mackenbach

Erasmus University Rotterdam

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Mall Leinsalu

National Institutes of Health

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Ramune Kalediene

Lithuanian University of Health Sciences

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Patrick Deboosere

Vrije Universiteit Brussel

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Enrique Regidor

Autonomous University of Madrid

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Bjørn Heine Strand

Norwegian Institute of Public Health

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