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Dive into the research topics where Barbara L. Lohman is active.

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Featured researches published by Barbara L. Lohman.


Journal of Medical Primatology | 1994

Mucosal immunization with a live, virulence-attenuated simian immunodeficiency virus (SIV) vaccine elicits antiviral cytotoxic T lymphocytes and antibodies in rhesus macaques.

Barbara L. Lohman; Micheal B. McChesney; Christopher J. Miller; Moses Otsyula; Christopher J. Berardi; Marta L. Marthas

An effective AIDS vaccine must protect against sexual transmission of human immunodeficiency virus (HIV). Therefore, vaccine regimens which stimulate antiviral immunity in the genital tract as well as in peripheral blood and systemic lymphoid tissues are needed. Here, we describe a method of immunization by direct inoculation of the vaginal submucosa with a live attenuated SIV, SIVmac1A11. Immunization by this route generated low levels of SIV‐specific IgG and IgA antibodies in serum and vaginal secretions and viral specific cytotoxic T lymphocyte (CTL) activity in peripheral blood.


Journal of Virology | 1994

A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge.

Barbara L. Lohman; Michael B. McChesney; Christopher J. Miller; E. McGowan; S. M. Joye; K. K. A. Van Rompay; Elizabeth Reay; L. Antipa; Niels C. Pedersen; Marta L. Marthas


Journal of Immunology | 1998

Nasal Immunization of Nonhuman Primates with Simian Immunodeficiency Virus p55gag and Cholera Toxin Adjuvant Induces Th1/Th2 Help for Virus-Specific Immune Responses in Reproductive Tissues

Koichi Imaoka; Christopher J. Miller; Mitsuru Kubota; Michael B. McChesney; Barbara L. Lohman; Masafumi Yamamoto; Kohtaro Fujihashi; Kenji Someya; Mitsuo Honda; Jerry R. McGhee; Hiroshi Kiyono


Journal of Immunology | 1995

Antiviral cytotoxic T lymphocytes in vaginal mucosa of simian immunodeficiency virus-infected rhesus macaques.

Barbara L. Lohman; Christopher J. Miller; Michael B. McChesney


Journal of Virology | 1990

Immunization with a live, attenuated simian immunodeficiency virus (SIV) prevents early disease but not infection in rhesus macaques challenged with pathogenic SIV.

Marta L. Marthas; Suganto Sutjipto; Joanne Higgins; Barbara L. Lohman; Judith Torten; Paul A. Luciw; P A Marx; Niels C. Pedersen


Journal of Virology | 1993

Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac.

Marta L. Marthas; R. A. Ramos; Barbara L. Lohman; K. K. A. Van Rompay; Ronald E. Unger; Christopher J. Miller; B. Banapour; Niels C. Pedersen; Paul A. Luciw


Journal of Virology | 1999

Mucosal Immunization of Cynomolgus Macaques with Two Serotypes of Live Poliovirus Vectors Expressing Simian Immunodeficiency Virus Antigens: Stimulation of Humoral, Mucosal, and Cellular Immunity

Shane Crotty; Barbara L. Lohman; Fabien X.-S. Lü; Shenbei Tang; Christopher J. Miller; Raul Andino


AIDS Research and Human Retroviruses | 1994

Reduced virus load in rhesus macaques immunized with recombinant gp160 and challenged with Simian immunodeficiency virus

Shabbir Ahmad; Barbara L. Lohman; Marta L. Marthas; Luis D. Giavedoni; Zahwa El-Amad; Nancy L. Haigwood; Carl J. Scandella; M. Gardner; Paul A. Luciw; Tilahun Yilma


Journal of Medical Primatology | 1992

Efficacy of live-attenuated and whole-inactivated simian immunodeficiency virus vaccines against vaginal challenge with virulent SIV.

Marta L. Marthas; Christopher J. Miller; Suganto Sutjipto; Joanne Higgins; Judith Torten; Barbara L. Lohman; Ronald E. Unger; Ramos Ra; Kiyono H; McGhee


Journal of Clinical Microbiology | 1991

Development of simian immunodeficiency virus isolation, titration, and neutralization assays which use whole blood from rhesus monkeys and an antigen capture enzyme-linked immunosorbent assay.

Barbara L. Lohman; Joanne Higgins; Marta L. Marthas; P A Marx; Niels C. Pedersen

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Marta L. Marthas

California National Primate Research Center

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Christopher J. Miller

California National Primate Research Center

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Paul A. Luciw

University of California

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Joanne Higgins

University of California

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Judith Torten

University of California

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M. Gardner

University of California

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