Barry S. Fogel

Bedside Cognitive Screening Instruments: A Critical Assessment

Bedside cognitive screening instruments are used increasingly in clinical and research settings to detect cognitive impairment and to quantify its severity. The authors review the five most frequently cited bedside screening tests that use an interview format and require brief administration times: the Mini-Mental State Examination, the Cognitive Capacity Screening Examination, Mattis Dementia Rating Scale, Kahns Mental Status Questionnaire, and the Short Portable Mental Status Questionnaire. The tests all have adequate inter-rater reliability, and adequate test-retest reliability has been established for three of the tests. All of the tests show close correspondence with clinical diagnoses of delirium and dementia and are useful for the diagnosis and quantification of these syndromes. However, there is currently no evidence that the tests increase the level of diagnostic accuracy achieved through clinical examination alone. All of the tests have substantial false-negative rates, with false-negative errors frequent among patients with focal lesions, particularly of the right hemisphere. False-positive errors may be more common among patients with less education and lower socioeconomic status. The tests reviewed do not detect many types of cognitive deficit that may bear critically on differential diagnosis and case management. Suggestions are given for further research on the current measures and for the development of new screening tests that would meet a broader range of clinical purposes.

Coping and depressive symptoms among young people with AIDS.

This study examined coping behaviors of people with AIDS, using a large sample (N = 736) that was both geographically and sociodemographically diverse. In-person interviews were conducted with people receiving AIDS-related medical or social services; follow-up interviews were conducted approximately 11 months later. Factor analyses of 16 coping behaviors revealed three factors: Positive Coping, Seeking Social Support, and Avoidance Coping. Respondents with a history of injected drug use, as compared with gay or bisexual men, had higher scores for Avoidance Coping and lower scores for Positive Coping. Each coping scale was significantly related to depressive symptoms in cross-sectional analyses. In longitudinal analyses that controlled for prior depressive symptoms, Positive Coping was significantly related to decreases in symptoms.

The development and initial validation of a sensitive bedside cognitive screening test.

Brief bedside cognitive examinations such as the Mini-Mental State Examination are designed to detect delirium and dementia but not more subtle or delineated cognitive deficits. Formal neuropsychological evaluation provides greater sensitivity and detects a wider range of cognitive deficits but is too lengthy for efficient use at the bedside or in epidemiological studies. The authors developed the High Sensitivity Cognitive Screen (HSCS), a 20-minute interview-based test, to identify patients who show disorder on formal neuropsychological evaluation. An initial study demonstrated satisfactory test-retest and interrater reliability. The HSCS was then administered to 60 psychiatric and neurological patients with suspected cognitive deficits but without gross impairment, who also completed formal neuropsychological testing. Results of both tests were independently classified as either normal, borderline, or abnormal. The HSCS correctly classified 93% of patients across the normal abnormal dichotomy and showed promise for characterizing the extent and severity of cognitive dysfunction.

Organization and development of combined medical-psychiatric units: Part 1

Abstract Key issues examined in this first of a two-part series on the organization and development of combined medical-psychiatric units include definition of the intended patient populations, features of the physical environment for both patients and staff, diagnostic and therapeutic capabilities, kinds of psychiatric therapy in relation to this particular therapeutic milieu, and the roles of other mental health practitioners. This evaluation, along with the subsequent discussion of associated features in Part 2, is intended to provide a comprehensive guide for assessing the feasibility of successfully operating a combined unit within a general hospital setting.

The High Sensitivity Cognitive Screen

Ceiling effects limit the utility of many established brief cognitive screening tests for detecting and measuring mild delirious states and prodromal disorders. The High Sensitivity Cognitive Screen (HSCS) (Faust & Fogel, 1989), a bedside test taking approximately 25 minutes to administer, may overcome this limitation. The test consists of a selection of moderately difficult items testing six major domains of neuropsychological performance: memory, language, attention/concentration, visual/motor, spatial, and self-regulation and planning. Reliability is adequate, and two separate concurrent validity studies show accuracy rates of 93% and 87% in classifying the overall result of comprehensive neuropsychological testing. HSCS performance is highly correlated with EEG results in medical psychiatric inpatients, and with functional status in HIV-infected community-dwelling subjects. The brevity and convenience of the HSCS and related instruments make them particularly useful in studies of elderly and chronically ill subjects.

Professional association membership by nursing facility administrators and quality of care.

This article compares 4,220 nursing homes whose administrators belonged to a long-term-care professional association to 12,322 nursing homes whose administrators did not belong to a long-term-care professional association. The research results show that professional membership is associated with higher quality of care on several measures and with a higher private-pay proportion. The study suggests that these facilities do not do better because they have more resources or because they care for less-challenging residents—they do better because they have a professional association as a resource.

A psychiatric unit becomes a psychiatric-medical unit: Administrative and clinical implications

Increasing awareness of the frequent concurrence of medical and psychiatric illness has led to a resurgence of interest in psychiatric-medical units. This paper describes the conversion of a 19-bed general hospital psychiatric unit to a psychiatric-medical model. The conversion involved hiring a full-time chief and changing priorities for elective admission, but did not involve major changes in staffing; community-based psychiatrists continued to admit the majority of patients. Arrangements were made for medical house staff coverage of emergent medical problems, while daily medical care remained in the hands of the psychiatrists and their private medical consultants. In the year following the transition numerous patients with combined acute medical and psychiatric illness not treatable in the previous model were accepted and successfully treated. Quantitative study of annual statistics from the pre- and posttransition years revealed the following: The average age of patients increased from 46 to 54 years. The proportion of patients over 65 increased from 19% to 34.9%. The proportion of patients with identified concurrent medical diagnoses increased from 54.7% to 69.1%. Dispositions to nursing homes and chronic care facilities decreased from 10.5% to 8.9%. Length of stay increased from 19.3 to 23.1 days. The average daily hospital bill for psychiatric inpatients rose by 24.6%, compared with a hospital-wide average increase of 16.3%. Although the change in model appeared to offer effective treatment to previously underserved patients, it implied a significant shifting of patients and of costs. Administrative implications are discussed, and a list of preconditions for a successful conversion are suggested.

Effect of Elective Surgery Under General Anesthesia on Mental Status Variables in Elderly Women and Men: 10-Month Follow-Up

Mental status changes were assessed and compared in 172 general surgical and orthopedic patients and 190 nonsurgical patients, all aged 55 and over, during a 10-month period. Assessments included a structured psychosocial questionnaire and standardized tests of cognition, affect, and function. The relationship of surgery, type of surgery, age, gender, and postoperative delirium to long-term postoperative decline was evaluated. Analyses of variance directly tested main effects pertaining to each of the five hypotheses and interactions of surgery with background variables. Hierarchical multiple regression analyses assessed the unique contributions of demographic and surgical variables to cognitive, affective, and functional change. None of the independent variables tested made a significant contribution to changes from baseline to long-term follow-up. The findings may be due to the physical and psychological health of this sample, and replication of this work in more impaired populations may be productive.

Cognitive Change After Elective Surgery in Nondemented Older Adults

The authors report the results of repeated cognitive function tests administered over 10 months to 82 patients between the ages of 55 and 82 who underwent elective surgery. The Mini-Mental State Exam (MMSE) score, 10 months after surgery, was modeled by a multivariate linear regression that included the baseline demographics, baseline cognitive functions, and immediate postoperative MMSE scores. Immediate postoperative MMSE scores were highly significant to 10-month postoperative MMSE scores not explained by baseline variables. The results suggest that immediate postoperative cognitive change may predict later postoperative cognitive decline.

Focal Cognitive Deficits Accentuated by Depression

A patient with a postoperative posterior right hemisphere lesion underwent neuropsychological testing during a major depressive episode, and again following remission of the depression. Qualitative visuoconstructive deficits typical of right hemisphere damage were present when the patient was depressed, but were absent following treatment of the depression. Verbal intelligence, cooperation, and vigilance were normal. The case suggests that depression may accentuate focal cognitive signs of fixed lesions in the absence of global impairment of function.