Benjamin Joseph Littler

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Featured researches published by Benjamin Joseph Littler.

Archive | 2010

Process for making modulators of cystic fibrosis transmembrane conductance regulator

Narendra Bhalchandra Ambhaikar; Robert Michael Hughes; Dennis James Hurley; Elaine Chungmin Lee; Benjamin Joseph Littler; Mehdi Numa; Stefanie Roeper; Urvi Sheth

Archive | 2010

Process for preparing azabicyclic compounds

Narendra Bhalchandra Ambhaikar; Brian Bear; Lev T. D. Fanning; Robert Michael Hughes; Benjamin Joseph Littler

Organic Process Research & Development | 2008

Development and Manufacture of the Inosine Monophosphate Dehydrogenase Inhibitor Merimepodib, VX-497

Adam R. Looker; Benjamin Joseph Littler; Todd A. Blythe; John R. Snoonian; Graham K. Ansell; Andrew D. Jones; Phil Nyce; Minzhang Chen; Bobbianna J. Neubert

Archive | 2012

Processes for making compounds useful as inhibitors of atr kinase

Jean-Damien Charrier; John Studley; Francoise Pierard; Steven Durrant; Benjamin Joseph Littler; Robert Michael Hughes; David Andrew Siesel; Paul Angell; Armando Urbina; Yi Shi

Organic Process Research & Development | 2010

Optimization of a Hydrogenation Process using Real-Time Mid-IR, Heat Flow and Gas Uptake Measurements

Benjamin Joseph Littler; Adam R. Looker; Todd A. Blythe

Organic Process Research & Development | 2015

Development of a Manufacturing Process for an HCV Protease Inhibitor Candidate Molecule

Benjamin Joseph Littler; Michael Aizenberg; Narendra Bhalchandra Ambhaikar; Todd A. Blythe; Timothy T. Curran; Vadims Dvornikovs; Young Chun Jung; Valdas Jurkauskas; Elaine C. Lee; Adam R. Looker; Hoa Luong; Theodore A. Martinot; David B. Miller; Bobbianna J. Neubert-Langille; Pieter A. Otten; Peter Jamison Rose; Piero L. Ruggiero

Archive | 2016

MODULATORS FOR ATP-BINDING CASSETTE TRANSPORTERS

Adam R. Looker; Benjamin Joseph Littler; Anusuya Choudhury; Christian Harrison; Ravikanth Veluri; Michael P. Ryan; Licong Jiang; Eduard Luss-Lusis

Archive | 2016

Telaprevir: From Drug Discovery to the Manufacture of Drug Substance

Gerald J. Tanoury; Stephen A. Eastham; Cristian Harrison; Benjamin Joseph Littler; Piero L. Ruggiero; Zhifeng Ye; Anne-Laure Grillo

Archive | 2013

SOLID FORMS OF (4-ISOPROPOXY-3-METHOXYPHENYL)(2'-METHYL-6'-(TRIFLUOROMETHYL)-3',4'-DIHYDRO-2'H-SPIRO[PIPERIDINE-4,1'-PYRROLO[1,2-A]PYRAZINE]-1-YL)METHANONE

Benjamin Joseph Littler; Ali Keshavarz-Shokri; Beili Zhang; Robert Michael Hughes

Archive | 2017

CRYSTALLINE FORMS OF C21H22CI2N 4O2.

Gary A Decrescenzo; Dean Welsch; Kathy Stavropoulos; Irina Nikolaevna Kadiyala; Ali Keshavarz-Shokri; Petinka Vlahova; Stephan X.M. Boerrigter; Alexander Aronov; Alexander N. Scangas; Benjamin Joseph Littler; Rossitza Gueorguieva Alargova

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