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Featured researches published by Benjamin Kase.


American Journal of Perinatology | 2012

Population standards of birth weight underestimate fetal growth abnormalities in diabetic pregnancies.

Benjamin Kase; Clint M. Cormier; Maged Costantine; Maria Hutchinson; Susan M. Ramin; George R. Saade; Manju Monga; Sean C. Blackwell

The objective of this study was to compare the frequency of abnormal fetal growth in women with diabetes mellitus (DM) using population-based birth weight (pop BW) percentiles compared with customized birth weight (cust BW) percentiles, which include adjustments for maternal race, parity, height, weight, and fetal sex. The study design comprised a retrospective cohort of singleton DM pregnancies delivered over a 1-year period (June 2007 to May 2008) from a single tertiary care university-based medical center. Inclusion criteria were gestational age >20 weeks at delivery, live birth, and absence of major chromosomal/structural abnormalities. Small for gestational age (SGA), <10th percentile, and large for gestational age (LGA), >90th percentile pregnancies were categorized based on pop BW or cust BW standards. There were significant differences in the rates of SGA (p < 0.004) and LGA (p < 0.001) between cust BW and pop BW methods. When comparing the two methods, pop BW did not identify 13/16 (81%) of SGA and 23/39 (59%) of LGA babies defined by cust BW methods. The use of cust BW calculation in a diabetic population identified a greater percentage of neonates with pathologic fetal growth compared with pop BW standards, suggesting that the population standard may underdiagnose abnormal fetal growth in diabetic pregnancies.


American Journal of Perinatology | 2011

Excessive Gestational Weight Gain in Women with Gestational and Pregestational Diabetes

Benjamin Kase; Clint M. Cormier; Maged Costantine; Maria Hutchinson; Susan M. Ramin; George R. Saade; Manju Monga; Sean C. Blackwell

We sought to determine the frequency of excessive gestational weight gain (GWG) and its impact on perinatal outcomes in women with gestational (GDM) and pregestational diabetes mellitus (DM). A retrospective cohort of diabetic women was studied. GWG was categorized by the 2009 Institute of Medicine guidelines. Perinatal outcomes were compared between those women with and without excessive GWG. There were 153 women who met study criteria. There was no difference in excessive GWG between women with GDM and pregestational DM (44.4% versus 38.5%, P = 0.51) or based on Whites class ( P = 0.17). After adjusting for confounders, excessive GWG was not associated with an increased rate of adverse perinatal outcomes (odds ratio 1.49, 95% confidence interval 0.56 to 2.35) and had similar associations with both pregestational DM and GDM. Although excessive GWG was common in our diabetic population, it was not associated with an increased rate of adverse perinatal outcomes.


American Journal of Obstetrics and Gynecology | 2013

570: Novel single nucleotide polymorphisms in the superoxide dismutase 1 (SOD1) and 2 (SOD2) genes among patients with non-syndromic myelomeningocele

Benjamin Kase; Hope Northrup; Kit Sing Au


American Journal of Obstetrics and Gynecology | 2012

336: Ultrasound derived estimated fetal weight using customized standards: does it improve prediction of adverse pregnancy outcomes?

Benjamin Kase; Sean C. Blackwell


American Journal of Obstetrics and Gynecology | 2012

337: Diagnosis of fetal growth restriction using customized growth standards in twin gestations

Carlos Carreno; Benjamin Kase; Brendan Connealy; Joan M. Mastrobattista; George R. Saade; Sean C. Blackwell


American Journal of Obstetrics and Gynecology | 2012

545: Can the addition of customized standards improve the prediction of fetal macrosomia and cesarean delivery for arrested labor?

Benjamin Kase; Sean C. Blackwell


/data/revues/00029378/v208i1sS/S0002937812018686/ | 2012

619: A history of prior preeclampsia is a major risk factor for preterm birth

Brendan Connealy; Carlos Carreno; Benjamin Kase; Laura Hart; Sean Blackwell; Baha Sibai


/data/revues/00029378/v208i1sS/S0002937812018194/ | 2012

570: Novel single nucleotide polymorphisms in the superoxide dismutase 1 ( SOD1 ) and 2 ( SOD2 ) genes among patients with non-syndromic myelomeningocele

Benjamin Kase; Hope Northrup; Kit Sing Au


/data/revues/00029378/v204i1sS/S000293781001519X/ | 2011

242: Does excessive gestational weight gain increase the risk for adverse perinatal outcomes in diabetic women?

Benjamin Kase; Clint M. Cormier; Maria Hutchinson; Susan M. Ramin; Manju Monga; Sean Blackwell

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Sean C. Blackwell

University of Texas Health Science Center at Houston

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Clint M. Cormier

University of Texas Health Science Center at Houston

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George R. Saade

University of Texas Medical Branch

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Manju Monga

University of Texas Health Science Center at Houston

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Maria Hutchinson

University of Texas Health Science Center at Houston

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Susan M. Ramin

Baylor College of Medicine

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Brendan Connealy

University of Texas Health Science Center at Houston

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Carlos Carreno

University of Texas Health Science Center at Houston

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Hope Northrup

University of Texas Health Science Center at Houston

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Kit Sing Au

University of Texas Health Science Center at Houston

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