Benyong Lou

μ-4,4′-Bipyridine-κ2N:N′-bis­[aqua­(4,4′-bi­pyridine-κN)(l-valinato-κ2N,O)copper(II)] dinitrate dihydrate

In the title dinuclear complex, [Cu2(C5H10NO2)2(C10H8N2)3(H2O)2](NO3)2·2H2O, each of the two l-valinate anions chelates a CuII center through the amino N and carboxylate O atom, forming a five-membered ring. A 4,4′-bipyridine molecule bridges two water-coordinated Cu atoms, each of which is connected to another 4,4′-bipyridine, giving rise to a square-pyramidal coordination geometry for the CuII centers. The dinuclear dications, nitrate anions and uncoordinated water molecules are linked into a two-dimensional structure.

Enantioselective permeations of amino acids through l-proline-modified gold nanochannel membrane: an experimental and theoretical study

Abstractl-Proline-modified gold nanochannel membrane (l-Pro-GNM) was prepared and applied for the enantioselective permeations of amino acid enantiomers including tyrosine (Tyr), tryptophan (Trp) and phenylalanine (Phe). Experimental results show that l-Pro-GNM has enantioselectivities for Tyr and Phe enantiomers. Furthermore, the chiral recognition mechanism was studied by density functional theory (DFT) and reduced density gradient (RDG). DFT computational results illustrate that the fundamental chiral recognition system contains two chiral selectors and one selectand, which can be used to evaluate the enantioselective efficiencies of other chiral compounds and the enantioselective ability of other potential amino acid-modified GNM. Finally, graphs obtained by RDG using Multiwfn show helpful visual interactions between the chiral selector and selectand. Results indicate that the electrostatic interaction and hydrogen bonding are responsible for the binding of the chiral selector and selectand, and the larger binding energy shows larger van der Waals interactions.

Crystal structure of 7-phenyl-7-(2,4,5-trimethyl-3,6-dioxo-cyclo-hexa-1,4-dien-1-yl)hepta-noate 1,3-dihy-droxy-2-(hy-droxy-meth-yl)propan-2-aminium monohydrate: a new solid form of seratrodast.

In the title compound, seratrodast has crystallized with trometamol to form a monohydrated salt. The carboxylic acid group of seratrodast has transferred its proton to the amino N atom of trometamol.

Poly[{μ(3)-3-[4-(1H-imidazol-1-yl-methyl)phen-yl]prop-2-enoato-κN:η:κO}copper(I)].

In the coordination polymer, [CuI(C13H11N2O2)]n, the CuI atom exists in a trigonal–planar geometry that is defined by the C=C unit, the imidazole N atom and carboxylate O atoms from three different ozagrel ligands, resulting in the formation of a three-dimensional framework.

2-Methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate

The title compound, amtolmetin guacil, C24H24N2O5, is a new gastroprotective non-steroidal anti-inflammatory drug. In the crystal structure, the drug molecule is linked into a one-dimensional structure along the c axis by weak N—H⋯O interactions between the amide groups. C—H⋯O and C—H⋯π interactions influence the packing.