Beom-Seok Kim

Identification of a resveratrol tetramer as a potent inhibitor of hepatitis C virus helicase

Hepatitis C virus (HCV) infection is responsible for various chronic inflammatory liver diseases. Here, we have identified a naturally occurring compound with anti‐HCV activity and have elucidated its mode of antiviral action.

Randomized trial to compare the dosage of darbepoetin alfa by administration route in haemodialysis patients

Aim:u2003 The doses of darbepoetin alfa required to maintain target haemoglobin levels after s.c. or i.v. administration when recombinant human erythropoietin (rHuEpo) treatment was replaced by darbepoetin alfa treatment in haemodialysis (HD) patients were compared.

Dual Micro-Thermopile Based Biocalorimeter for Enzyme-Substrate Reaction

This paper presents a new design of silicon-based biocalorimeter made with dual thermopiles and a microfluidic channel introducing a splitting and mixing flow. The dual-thermopile was fabricated with chromium and copper using microelectromechanical system (MEMS) technique, and the microfluidic channel was made of PDMS using a soft-lithography. Each thermopile consists of 26 Cr/Cu thermocouple pairs. The sensitivity of each thermocouple is 20.0 muV/K and the total sensitivity of thermopile is 519.2 muV/K. This dual-thermopile system enables biocalorimeter to acquire the reliable data in a rapid and convenient manner because it detects biochemical reaction and reference temperature simultaneously.

Measurement of Adiabatic Wall Temperature in Compressible High Speed Impinging jets using Infra-red Camera

this paper, we report experimental investigations on measurement of adiabatic wall temperature on a flat 2-D plate of high-speed impinging jet made by circular-shape nozzle at steady state condition using infra-red camera. Experiments have been conducted for the Reynolds number of 187,000 according to the change of nozzle-to-plate distance. Dimensionless number, recovery factor, has been used to represent the measured adiabatic wall temperature. And we compared the result obtained by using infra-red camera with that obtained by using thermocouple.