Bernard Peison

Paget's disease of the nipple simulating malignant melanoma in a black woman.

A lesion of Pagets disease arising in the skin of the nipple in a black woman is reported. The lesion simulated histologically a malignant melanoma because of the abundance of melanin within neoplastic cells in the epidermis as well as within the underlying ductal carcinoma of the breast. It was only after differential staining that the diagnosis of Pagets disease could be substantiated unequivocally.

Multicentric basal cell carcinoma of penile skin

A multicentric basal cell carcinoma of the penile skin is reported. The skin adjacent to the tumor showed changes similar to those observed in sun-damaged skin. Inasmuch as the patient denied sunbathing in the nude, causation is unclear, but sun may have played a role in the genesis of the tumor.

Primary plasmacytoma of the gingiva

Abstract A primary plasmacytoma of the upper gingiva is reported, and histologic criteria for distinguishing it from plasma cell granuloma are described.

Adenomyoma of the ileum

mately 35 to 36 weeks’ gestation. Biweekly urinary estriol levels were reported as normal. An oxytocin challenge test on November 28, 1975, was positive and suggestive of a loss of uteroplacental oxygen transferring capacity. A cesarean section was performed on November 28, 1975. A viable male infant of 9 pounds, 4 ounces, was delivered. The mother and baby did very well following the delivery. Following delivery, the patient had menstrual periods about every 35 days. An endometrial biopsy specimen was taken on August 24, 1976, the 20th day of the cycle. The tissue was reported as early secretory endometrium, free of any tumor. Another endometrial biopsy specimen was taken in January, 1977. Again the pathology report stated the tissue was free of tumor. She has expressed a wish to become pregnant again.

Primary extramedullary plasmacytoma of the omentum associated with recurrent adenocarcinoma of the colon: first case report.

Extramedullary plasmacytomas are rare tumors, with 272 cases reported in the literature in English. Less than 10 per cent of these are located in the gastrointestinal tract. This report documents the first primary plasmacytoma of the omentum in association with a recurrent colonic adenocarcinoma. Extramedullary plasmacytoma, a B cell neoplasm, characteristically arises in areas containing lymphoid tissue. In our case the tumor most likely arose in a lymph node or nodes in the omental fat, with subsequent replacement of the entire greater omentum and involvement of the colonic serosa by direct extension. Although the extent and nature of the association between myeloma and carcinoma remain obscure, a review of the literature suggests that such association may occur more frequently than has been supposed. Further investigation would appear to be warranted.