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Dive into the research topics where Bernd Krist is active.

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Featured researches published by Bernd Krist.


Expert Opinion on Investigational Drugs | 2000

The role of NPY in metabolic homeostasis: implications for obesity therapy

Heike A. Wieland; Bradford S. Hamilton; Bernd Krist; Henri Doods

Neuropeptide Y (NPY) is a 36 amino acid amidated peptide which has now emerged as an important regulator of feeding behaviour. Upon intracerebroventricular (icv.) administration, NPY produces a pronounced feeding response in a variety of species. The actions of NPY are believed to be mediated by a family of receptor subtypes named Y1 - y6. Recent studies suggest that the Y1 and Y5 receptor subtypes are intimately involved in NPY induced feeding. This review presents preclinical data obtained with receptor subtype selective agonists and antagonists as well as findings from knockout mice. These new data suggest that NPY receptor antagonists may become an additional option for treating human obesity.


Archive | 2002

Pyrimidine derivatives, pharmaceutical agent containing said compounds, use and method for making same

Georg Dahmann; Frank Himmelsbach; Helmut Wittneben; Alexander Pautsch; Anthony S. Prokopowicz; Bernd Krist; Gisela Schnapp; Martin Steegmaier; Martin Lenter; Andreas Schoop; Steffen Steurer; Walter Spevak


Archive | 2007

Thiazolyl-Dihydro-Indazoles

Bodo Betzemeier; Trixi Brandl; Steffen Breitfelder; Ralph Brueckner; Thomas Gerstberger; Michael Gmachl; Matthias Grauert; Frank Hilberg; Christoph Hoenke; Matthias Hoffmann; Maria Impagnatiello; Dirk Kessler; Christian Klein; Bernd Krist; Udo Maier; Darryl Mcconnell; Charlotte Reither; Stefan Scheuerer; Andreas Schoop; Norbert Schweifer; Oliver Simon; Martin Steegmaier; Steffen Steurer; Irene Waizenegger; Ulrike Weyer-Czernilofsky; Andreas Zoephel


Archive | 2002

Pyrimidine derivatives, pharmaceutical compositions containing these compounds, the use thereof and process for the preparation thereof

Georg Dahmann; Frank Himmelsbach; Helmut Wittneben; Alexander Pautsch; Anthony S. Prokopowicz; Bernd Krist; Gisela Schnapp; Martin Steegmaier; Martin Lenter; Andreas Schoop; Steffen Steurer; Walter Spevak


Archive | 2002

Carbazole derivatives and their use for the preparation of pharmaceutical compositions for the treatment of npy related diseases

Klaus Rudolf; Rudolf Hurnaus; Wolfgang Eberlein; Wolfhard Engel; Heike-Andrea Wieland; Bernd Krist


Archive | 2005

INDOLINONES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS

Darryl Mcconnell; Ulrike Weyer-Czernilofsky; Maria Impagnatiello; Steffen Steurer; Ralph Brueckner; Bernd Krist; Bodo Betzemeier; Frank Hilberg; Armin Heckel; Gerald Juergen Roth; Joerg Kley; Thorsten Lehmann-Lintz


Archive | 2007

Compounds and compositions for treating obesity

Kilian W. Conde-Frieboes; Michael Ankersen; Ulrich Sensfuss; Birgitte Schjellerup Wulff; Henning Thøgersen; Philipp Lustenberger; Klaus Rudolf; Bernd Krist; Stephan Georg Müller; Dirk Stenkamp; Marcus Schindler; Heike A. Wieland; Kirsten Arndt


Archive | 2004

Arylpiperazine-benzoylamide derivatives useful as pharmaceutical agents

Bodo Betzemeier; Bernd Krist; Darryl Mcconnell; Steffen Steurer; Maria Impagnatiello; Ulrike Weyer-Czernilofsky; Frank Hilberg; Ralph Brueckner; Georg Daiimann; Armin Heckel; Joerg Kley; Thorsten Lehmann-Lintz; Gerald Jürgen Roth


Archive | 2005

Pyrrolobenzimidazolones and their use as anti-proliferative agents

Darryl McConnel; Steffen Steurer; Bernd Krist; Ulrike Weyer-Czernilofsky; Maria Impagnatiello; Matthias Treu; Iris Kauffmann-Hefner; Pilar Garin-Chesa; Andreas Schnapp


Archive | 2002

DERIVADOS DE PIRIMIDINA, AGENTES FARMACEUTICOS QUE CONTIENE DICHOS COMPUESTOS, USO Y METODO PARA SU OBTENCION.

Georg Dahmann; Frank Himmelsbach; Bernd Krist; Martin Lenter; Alexander Pautsch; Anthony S. Prokopowicz; Gisela Schnapp; Andreas Schoop; Walter Spevak; Martin Steegmaier; Steffen Steurer; Helmut Wittneben

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Gisela Schnapp

German Cancer Research Center

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