Beth Ann Schubert
Procter & Gamble
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Publication
Featured researches published by Beth Ann Schubert.
Journal of Colloid and Interface Science | 2014
Yihui Yang; Alessandro Corona; Beth Ann Schubert; Robert C. Reeder; Michael A. Henson
Second generation lipid systems for the delivery of bioactive compounds have been developed by mixing a liquid carrier oil with a solid lipid to form so-called nanostructured lipid carriers (NLCs). In this study, we investigated the effect of different liquid carrier oils on the crystallization and aggregation behavior of tristearin NLC dispersions. We found that NLC suspension stability was strongly affected by the type and amount of the carrier oil. As the oil concentration was increased, the crystallization and melting temperatures decreased, the polymorphic transformation rate increased, the particles became more spherical, and suspension stability was enhanced. These results suggest that oil trapped within the growing crystal matrix accelerated polymorphic transformation but retarded the large shape change normally associated with the transformation. We also found that considerably less surfactant was necessary to produce stable NLC suspensions than was required to stabilize solid lipid nanoparticle (SLN) suspensions without a carrier oil. Based on preliminary simulation results, we hypothesized that improved NLC suspension stability was attributable to both reduced particle shape change, which created less new surface area to be covered by surfactant, and increased mobility of surfactant molecules, which resulted in available surfactant being more efficient at covering created surface area.
Archive | 2011
Alessandro Corona; Brian W. Everingham; Gayle Marie Frankenbach; Heidi Hsieh; Rajan Keshav Panandiker; Brian Joseph Roselle; Beth Ann Schubert; Mark Robert Sivik; Kerry Andrew Vetter; Gregory Thomas Waning
Archive | 2009
Alessandro Corona; Brian W. Everingham; Gayle Marie Frankenbach; Rajan Keshav Panandiker; Beth Ann Schubert; Mark Robert Sivik; Kerry Andrew Vetter; Gregory Thomas Waning
Archive | 2010
Qing Stella; Edward Dewey Smith; Todd Ryan Thompson; Beth Ann Schubert; Nathan Ray Whitely; Cynthia Ann Garza
Archive | 2009
Alessandro Corona; Brian W. Everingham; Gayle Marie Frankenbach; Rajan Keshav Panandiker; Mark Robert Sivik; Beth Ann Schubert; Mario Elmen Tremblay; Kerry Andrew Vetter; Gregory Thomas Waning; Jeffrey Scott Weaver
Archive | 2009
Alessandro Corona; Brian W. Everingham; Gayle Marie Frankenbach; Rajan Keshav Panandiker; Beth Ann Schubert; Mark Robert Sivik; Kerry Andrew Vetter; Gregory Thomas Waning
Archive | 2012
Eric Scott Johnson; James Anthony Staudigel; Sean Michael Renock; Beth Ann Schubert; Mark William Hamersky
Journal of Surfactants and Detergents | 2014
Dongcui Li; Beth Ann Schubert; Norman J. Wagner
Journal of Colloid and Interface Science | 2016
Wei Wang; Eric Scott Johnson; Tommy Nylander; Pete Ellingson; Beth Ann Schubert; Lennart Piculell
Archive | 2016
Beth Ann Schubert; Luke Andrew Zannoni; Robert Joseph Mcchain