Bhaskar Ghosh

Primary laryngeal aspergillosis in the immunocompetent state: a clinical update.

Laryngeal aspergillosis is known to occur in immunocompromised states, particularly in diabetes mellitus, tuberculosis, and human immuno-deficiency virus (HIV) infection, and is associated with use of inhalational steroids and cytotoxic drugs. Primary laryngeal aspergillosis is rare, especially in immunocompetent patients, with very few reported cases to date. It often mimics the pre-malignant and malignant conditions of larynx, and responds well to antifungals. This report presents a case of primary laryngeal aspergillosis in an immunocompetent middle-aged woman, and explores the current pool of evidence regarding its pathogenesis and clinical aspects. To date, this represents the only comprehensive review on the topic.

Juvenile nasopharyngeal angiofibroma-three years experience.

Juvenile nasopharyngeal angiofibroma is a rare, highly vascular, histologically benign but locally invasive tumour, affecting almost exclusively adolescent males. This is a prospective study of 37 patients with juvenile nasopharyngeal angiofibroma treated during 3 years in our institution. The various pharyngeal and extrapharyngeal presentation staging and proper surgical approaches as per extensions are discussed here with reference to past reports.

Ameloblastic carcinoma of mandible: facts and dilemmas

Ameloblastic carcinoma is a rare malignant odontogenic tumor and is considered as the malignant counterpart of ameloblastoma with features of both benign and malignant histology. It may arise de novo or from a long-standing ameloblastoma and is locally aggressive with a propensity for metastasis. With limited documentation, little is known about its pathobiogenesis, with no universal guidelines for management. For clinicians, differentiating ameloblastic carcinoma from ameloblastoma and malignant ameloblastoma in a patient presenting with a suspicious jaw tumor is a challenge due to overlapping clinical features, inconclusive cytology/biopsy reports, different management approaches and inadequate follow-up. Proper knowledge of the disease entity and a high index of suspicion are essential. Here we elaborate the dilemmas in diagnosis and management of ameloblastic carcinoma through presentation of a representative case in a 56-year-old man presenting with a tumor in the mandible.

Contact Headache and Its Management: Our Experience

Headache and facial pain is very common and distressing complaint. Due to its multifactorial origin often it remains undiagnosed and inadequately treated. In this study strong relationship between nasal mucosal contact point and reason for unresponsive headache is found and various nasal surgeries are found to be quite helpful in treating these conditions.

Synovial sarcoma of parapharyngeal and retropharyngeal space: A case report

Synovial sarcoma is a rare tumour of head and neck. It was first described by Pack and Ariel in 1950. Synovial sarcoma is said to be the commonest sarcoma of hands and feet and they are usually found adjacent to the articular surfaces. They rarely occur in extra-articular sites originating from bursa or tendon sheaths. Parapharyngeal space appears to be the site of predilection in most of the cases occurring in the head and neck region. One such case is being reported here along with its management and review of literature.

Cystic squamous cell carcinoma of the neck: could a second metastatic focus help?

Squamous cell carcinoma of the neck presenting clinically as predominantly cystic lesion has often been considered as branchiogenic carcinoma in the past. However, such cystic lesions presently constitute a distinct form of head-neck metastasis, and a co-existent second metastatic focus could supposedly help distinguish them from branchiogenic carcinoma. We here present a case where, although the primary remained elusive, the associated spinal metastasis precluded us from diagnosing a cystic squamous cell carcinoma as branchiogenic carcinoma. Thus a second metastatic focus, if found, could add to the existing knowledge to distinguish between a cystic squamous cell carcinoma and the so-called branchiogenic carcinoma, especially when the primary could not be found.