Bhertha Miyuki Tamura

Allergic reaction to botulinum toxin: positive intradermal test.

Botox (Allergan, Irvine, CA) was introduced in Brazil in 1992 for the treatment of hyperhidrosis and neurologic disorders, and in 2000 it was approved for cosmetic use. Each Botox vial contains 100 U of botulinum toxin (BTX), 0.9 mg of sodium chloride, and 0.5 mg of human albumin, and its protein load is 5 ng. Prosigne (Lanzhou Institute of Biological Products/Cristália, Lanzhou, China), each vial containing 50 or 100 U of BTX, was approved for the treatment of hyperhidrosis, neurologic disorders, and hyperfunctional lines in 2005. The excipients in Prosigne are 5 mg porcine gelatin (Haemacell), 25 mg of dextran, and 25 mg of sucrose, and the protein load is 4.0 to 5.0 ng/100 U of BTX.

Revisão da literatura: afecções auriculares parte 1: traumas físicos e por alteração térmica

The ear is a structure with anatomical peculiarities. It is located in an area exposed to trauma and susceptible to a series of dermatoses that are often underdiagnosed by dermatologists and deserve attention. A literature review was carried out including the embryology and anatomy of the auricular pavilion, as well as the diagnosis and treatment of traumatic lesions of physical nature and due to changes in temperature, among others.