Blaise Aguirre
McLean Hospital
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Featured researches published by Blaise Aguirre.
Child and Adolescent Psychiatric Clinics of North America | 2015
Jeff Q. Bostic; Michael D. Nevarez; Mona Potter; Jefferson B. Prince; Margaret M. Benningfield; Blaise Aguirre
Developmentally sensitive efforts to help students learn, practice, and regularly use mindfulness tactics easily and readily in and beyond the classroom are important to help them manage future stresses. Mindfulness emphasizes consciously focusing the mind in the present moment, purposefully, without judgment or attachment. Meditation extends this to setting aside time and places to practice mindfulness, and additionally, yoga includes physical postures and breathing techniques that enhance mindfulness and meditation. Several mindfulness programs and techniques have been applied in schools, with positive benefits reported. Some elements of these programs require modifications to be sensitive to the developmental state of the children receiving mindfulness training.
Personality and Mental Health | 2017
Marianne Goodman; Irene Alvarez Tomas; Christina M. Temes; Garrett M. Fitzmaurice; Blaise Aguirre; Mary C. Zanarini
OBJECTIVE Prevalence data on self-mutilation and suicide attempts for adolescent borderline personality disorder (BPD) are currently not available. The purpose of this paper was to determine the frequency and methods of two forms of physically self-destructive acts (i.e. self-mutilation and suicide attempts) reported by adolescent borderline inpatients in one of the largest samples to date and to compare these results with a similarly diagnosed and assessed group of adult borderline inpatients. METHODS A total of 104 adolescent inpatients with BPD and 290 adult inpatients with BPD were interviewed about their lifetime history of physically self-destructive acts. RESULTS The overall rates of self-mutilation (about 90%) and suicide attempts (about 75%) were similar during index admission for both adolescent and adult borderline patients. However, adolescents reported significantly higher rates of extreme levels of lifetime self-mutilation (e.g. >25 and >50 episodes) and cutting in particular, as compared with adult BPD. In contrast, borderline adults were significantly more likely to report a history of numerous (five or more) suicide attempts than adolescents with BPD. CONCLUSIONS Self-mutilation and suicide attempts among adolescent borderline patients are prevalent and serious. Taken together, these results suggest that extreme levels of self-mutilation distinguish adolescent BPD from adults with BPD. Copyright
Comprehensive Psychiatry | 2016
Cynthia Kaplan; Naomi Tarlow; Jeremy G. Stewart; Blaise Aguirre; Gillian Galen; Randy P. Auerbach
BACKGROUND Borderline personality disorder (BPD) is characterized by greater engagement in non-suicidal self-injury (NSSI) and suicidality. The aim of the study is to test whether the occurrence of child abuse contributes to these high-risk behaviors in BPD youth. MATERIALS AND METHODS BPD female youth aged 13-21years with (n=29) and without (n=29) a history of child abuse were administered clinical interviews assessing diagnostic history, child abuse, NSSI and suicidality (i.e., ideation, plans, and attempts). NSSI and suicidality were subsequently reevaluated at the 1- and 2-month follow-up assessments. RESULTS Several findings emerged. First, relative to BPD youth without abuse, the abuse group reported greater past NSSI; however, no significant differences emerged in the follow-up period. Second, the occurrence of child abuse was associated with a 5-fold increase in the rate of lifetime suicide attempts relative to the no abuse group and additionally, prospectively predicted suicide ideation (but not attempts). Last, exploratory analyses indicated that the co-occurrence of physical and sexual abuse was associated with greater past NSSI and suicidality as compared to the no abuse and sexual abuse only participants. CONCLUSION As a whole, child abuse - particularly co-occurring physical and sexual abuse - increases risk for NSSI and suicidality among BPD youth, which may have important treatment implications in this high-risk population.
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging | 2016
Randy P. Auerbach; Naomi Tarlow; Erin Bondy; Jeremy G. Stewart; Blaise Aguirre; Cynthia Kaplan; Wenhui Yang; Diego A. Pizzagalli
BACKGROUND Borderline personality disorder (BPD) is debilitating, and theoretical models have postulated that cognitive-affective biases contribute to the onset and maintenance of BPD symptoms. Despite advances, our understanding of BPD pathophysiology in youth is limited. The present study used event-related potentials (ERPs) to identify cognitive-affective processes that underlie negative self-referential processing in BPD youth. METHODS Healthy females (n = 33) and females with BPD (n = 26) 13 to 22 years of age completed a self-referential encoding task while 128-channel electroencephalography data were recorded to examine early (i.e., P1 and P2) and late (late positive potential [LPP]) ERP components. Whole-brain standardized low-resolution electromagnetic tomography explored intracortical sources underlying significant scalp ERP effects. RESULTS Compared to healthy females, participants with BPD endorsed, recalled, and recognized fewer positive and more negative words. Moreover, unlike the healthy group, females with BPD had faster reaction times to endorse negative versus positive words. In the scalp ERP analyses, the BPD group had greater P2 and late LPP positivity to negative as opposed to positive words. For P2 and late LPP, whole-brain standardized low-resolution electromagnetic tomography analyses suggested that females with BPD overrecruit frontolimbic circuitry in response to negative stimuli. CONCLUSIONS Collectively, these findings show that females with BPD process negative self-relevant information differently than healthy females. Clinical implications and future directions are discussed.
Personality and Mental Health | 2017
Dana B. Borkum; Christina M. Temes; Laura R. Magni; Garrett M. Fitzmaurice; Blaise Aguirre; Marianne Goodman; Mary C. Zanarini
OBJECTIVE Existing literature on the aetiology of borderline personality disorder (BPD) has primarily focused on pathological childhood experiences, while little to no research has been conducted on protective factors that may serve to ameliorate these symptoms. The current study attempts to fill this gap in the literature by comparing the rates of childhood protective factors among adolescents with BPD, psychiatrically healthy adolescents and adults with BPD. METHODS One hundred and four subjects were adolescent inpatients between the ages of 13 and 17 who met Revised Diagnostic Interview for Borderlines and Diagnostic and Statistical Manual of Mental Disorders Fourth Edition criteria for BPD. Sixty were age-matched psychiatrically healthy comparison subjects. Two hundred and ninety subjects were adult inpatients between the ages of 18 and 35 who met Revised Diagnostic Interview for Borderlines and Revised Diagnostic and Statistical Manual of Mental Disorders Third Edition criteria for BPD. All three groups were interviewed by using the Revised Childhood Experiences Questionnaire, a semi-structured interview that assesses pathological and protective childhood experiences. RESULTS Psychiatrically healthy adolescents reported significantly higher rates of 4 out of 18 protective factors than adolescents with BPD. Adolescents with BPD reported significantly higher rates of 5 of these 18 protective factors than adults with BPD. Adults with BPD were significantly more likely to endorse having a steady after school or weekend work record than adolescents with BPD. CONCLUSIONS Taken together, the results of this study suggest that adolescents meeting criteria for BPD report lower rates of some protective factors than psychiatrically healthy adolescents. They also suggest that they have higher rates of some protective factors than adults with BPD. Copyright
Personality and Mental Health | 2017
Ueli Kramer; Christina M. Temes; Laura R. Magni; Garrett M. Fitzmaurice; Blaise Aguirre; Marianne Goodman; Mary C. Zanarini
OBJECTIVE Little is known about the psychosocial functioning of adolescents with borderline personality disorder (BPD). The main objective of this paper is to compare the psychosocial functioning of a group of adolescents with BPD to a group of psychiatrically healthy adolescents. METHODS The present cross-sectional study included 104 adolescent inpatients with BPD, compared with 60 age-matched psychiatrically healthy comparison subjects. All participants were rigorously diagnosed using three semi-structured interviews: the Structured Clinical Interview for DSM-IV Childhood Diagnoses, the Revised Diagnostic Interview for Borderlines and the Childhood Interview for DSM-IV Borderline Personality. All subjects were also interviewed using the adolescent version of the Background Information Schedule to assess multiple facets of psychosocial functioning. RESULTS Adolescents with BPD rated their relationships with their parents as significantly less positive, were more likely to date, but spent more time alone than their healthy counterparts. In addition, adolescents with BPD reported significantly more problems at work and school (i.e. lower frequency of having a good work or school history, higher frequency of being suspended or expelled from school) and significantly lower rates of participation in extra-curricular activities than their healthy counterparts. CONCLUSIONS Taken together, the results of this study suggest that adolescents with BPD are more impaired in both the social and vocational areas of functioning than psychiatrically healthy comparison subjects. They might also suggest that an overlooked area of strength concerns their relationships with peers. Copyright
Evidence-Based Practice in Child and Adolescent Mental Health | 2018
Lyndsey R. Moran; Cynthia Kaplan; Blaise Aguirre; Gillian Galen; Jeremy G. Stewart; Naomi Tarlow; Randy P. Auerbach
ABSTRACT Dialectical behavior therapy (DBT) is an empirically supported treatment for borderline personality disorder (BPD) in adults; however, fewer studies have examined outcomes in adolescents. This study tested the effectiveness of an intensive 1-month residential DBT treatment for female adolescents meeting criteria for BPD. In addition, given well-established associations between BPD symptoms and childhood abuse, the impact of abuse on treatment outcomes was assessed. Participants were female youth (n = 53) ages 13–20 years (M = 17.00, SD = 1.89) completing a 1-month residential DBT program. At pretreatment, participants were administered a diagnostic interview and self-report measures assessing BPD, depression, and anxiety symptom severity. Following 1 month of treatment, participants were readministered the self-report instruments. Results showed significant pre- to posttreatment reductions in both BPD and depression symptom severity with large effects. However, there was no significant change in general anxious distress or anxious arousal over time. The experience of childhood abuse (sexual, physical, or both) was tested as moderator of treatment effectiveness. Although experiencing multiple types of abuse was related to symptom severity, abuse did not moderate the effects of treatment. Collectively, results indicate that a 1-month residential DBT treatment with adolescents may result in reductions in BPD and depression severity but is less effective for anxiety. Moreover, although youth reporting abuse benefited from treatment, they were less likely to achieve a clinically significant reduction in symptoms.
Archive | 2016
Blaise Aguirre
More than for other psychiatric disorders, people with BPD are thought to be more capable of controlling their socially “unacceptable” behavior, and yet often they cannot because they do not have the skill set to manage relationships and emotions. And so, and as research as well as my own professional experience shows, the mental health profession responds with less sympathy and optimism toward people who have this disorder. We, the mental health professionals, are to blame for the stigma attached to BPD, and it is up to us to repair the damage. We can do this through compassionate understanding, education, the removal of judgmental language, and the provision of evidence-based care.
Archive | 2014
Blaise Aguirre; Janna Hobbs; Michael Hollander
The pediatrician and psychoanalyst Donald Winnicott said: “There is no such thing as a baby, there is a baby and someone.” This statement captures the reality that a human baby cannot exist on its own. To see the infant as an individual completely separate from its caregiver misses the essential nature of the child’s utter dependence on another person.
Journal of the American Academy of Child and Adolescent Psychiatry | 1999
Blaise Aguirre