Bonawentura Rajewska-Więch

Space-based estimation of the solar UV-B doses for psoriasis heliotherapy in Poland using OMI data for the period 2005-2011.

A UV model is proposed to reconstruct the biologically weighted doses at the ground-level, erythemal, vitamin D(3), and antipsoriatic effective doses, based on the space data from the Ozone Monitoring Instrument on board of NASA EOS Aura spacecraft for the period 2005-2011. The model is training using the results of spectral UV measurements carried out at Belsk, Poland. The model outcome is verified using the UV spectra measured at Hradec Kralove, Czech Republic. The model uncertainty is almost the same for all examined action spectra and comparable to that found in earlier studies on differences between the satellite overpasses and ground-based erythemal data. Antipsoriatic doses, taken during 2h exposure periods near local noon, are reconstructed for selected sites in Poland to find if heliotherapy would be an alternative to standard treatment of psoriasis by tube irradiation in medical cabinets. Mountain-resort in the southern Poland, Zakopane, and rural-site in Central Poland, Belsk, are among the best location of potential heliotherapy centers in Poland for late spring/summer season. Łeba, resort on the Baltic Sea coast, is a potential heliotherapy center in June and July. The methodology to disclose possible heliotherapy periods over the territory of Poland could be extended to any region. It would help to prepare an optimal schedule of antipsoriatic heliotherapy that accounts for local weather conditions and medical standards of using UV cabinets.

Trends in the ozone vertical distribution from the Umkehr observations at Belsk 1963–2007

The Umkehr observations at Belsk (52° N, 21° E) are homogenized for the period 1963 to 2007, taking into account step changes in the R–N tables and re-evaluated total ozone values. Ozone content in the Umkehr layers is calculated by the newest retrieval (UMK04). Trends in the ozone content in the Umkehr layers are calculated in time series with the natural ozone fluctuations due to the 11 year solar activity and quasi-biennial oscillations removed. The negative trend in total ozone (∼3.5% per decade), found for the period 1980 to 1995, is due to the ozone depletion in the lower and mid-stratosphere (up to 23.5 km). Afterwards, the trends in total ozone and in lower and mid-stratospheric ozone are not statistically significant. In the upper stratosphere (> 37 km) the trends in the period 1996 to 2007 are positive and of ∼3–5% per decade. The occurrence of the positive trend after 1995 is in line with the Montreal Protocol regulations on ozone-depleting substances.

Effectiveness of heliotherapy for psoriasis clearance in low and mid-latitudinal regions: A theoretical approach

The action spectrum for psoriasis clearance is reconstructed taking into account the results obtained in the early 1980s. The antipsoriatic action spectrum is used for weighting the medical cabinet UV spectra, and the solar spectra measured in San Diego (USA) and Belsk (Poland). The mean cumulative antipsoriatic effective dose of 450 mJ cm(-2), due to TL-01 (UVB narrowband) tubes, is taken by a patient with skin phototype II during routine 20 phototherapy sessions carried out in a phototherapy cabinet in the Medical University of Łódz. Thus, the daily mean dose of value 22.5 mJ cm(-2) is proposed as the threshold for daily solar dose for numbers of out-door exposures to clear psoriasis. We assume that the heliotherapy will last a whole month with every day 2h exposition to the direct sunlight around local noon. The heliotherapy will be successful if weather conditions permit at least 20 days with the daily exposure over the threshold. The minimum cumulative ambient erythemal dose, necessary for psoriasis clearance, is estimated as 144 standard erythema dose (SED) for the whole heliotherapy period. We find that heliotherapy could be effectively used in March through October (San Diego) and in June through August (Belsk). Thus, the heliotherapy against psoriasis is possible not only at southern resorts but even at the mid-latitude sites.

Optimal vitamin D3 daily intake of 2000IU inferred from modeled solar exposure of ancestral humans in Northern Tanzania.

Recently, high serum 25-hydroxyvitamin D concentration (~110nmol/L) was found in the Hadza tribe still keeping ancient hunter-gather life style. This level could serve as optimal vitamin D level that was built during millennia of human evolution. The personal vitamin D3 effective solar exposures of the Hadza adults are estimated using radiative model simulations with input from the satellite observations over lake Eyasi (3.7°S, 35.0°E). The calculations are carried out assuming the Hadza typical clothing habits and specific scenarios of the out-door activity comprising early morning and late afternoon working time in sun and prolonged midday siesta in the shade. The modeled doses received by the Hadza are converted to the vitamin D3 effective daily doses pertaining to the lighter skinned persons. We propose a novel formula to get adequate vitamin D level - exposure of 1/3 MED around local noon to 1/3 part of the whole body during warm sub-period of the year in the low- and mid-latitude regions. Such daily solar exposure is equivalent to ~2000IU of vitamin D3 taken orally. For many contemporary humans with limited out-door activity habit achieving such daily norm requires vitamin D3 supplementation of 2000IU throughout the whole year.

Perspectives of the antipsoriatic heliotherapy in Poland

Statistical analysis of the daily course of exposures to TL-01 tube radiation for 93 psoriatic patients from the Medical University of Łódź during 20-day phototherapy shows that the dose of 1 J/cm(2) represents a unit of single exposure necessary for psoriasis healing. This value is converted to the antipsoriatic effective dose of 317.9 J/m(2) using the TL-01 lamp irradiance spectrum and the antipsoriatic action spectrum. It is proposed that the daily exposure of 317.9 J/m(2) serves as the standard antipsoriatic dose (SAPD) providing a link between the cabinet and the out-door exposures and it could be used for planning heliotherapy in Poland. A model is proposed to calculate ambient antipsoriatic doses for 3 h exposures around the local noon (9 am-12 am GMT) based on satellite measurements of ozone and cloud characteristics. The model constants are determined by a comparison with pertaining antipsoriatic doses measured by the Brewer spectrophotometer in central Poland. It is found that 3 h exposures to solar radiation in the period 15 May-15 September provides the mean (2005-2013) doses in the range 2.7-3.1 SAPD over Poland. Thus, heliotherapy could be treated as an alternative to the cabinet phototherapy for almost 4 months. It seems that the most effective site for antipsoriatic heliotherapy is the south/east part of Poland (the Bieszczady Mountains). The heliotherapy could be carried out in existing national health centers equipped with the standard easy-to-use biometers for on-line monitoring of UV level and controlling duration of sunbathing to avoid erythema risks. It is even possible to control the antipsoriatic heliotherapy by a patient himself, using low-cost hand-held instruments measuring UV index.

Impact of interannual meteorological variability on total ozone in northern middle latitudes: A statistical approach

The midwinter (January-February) and summer (June-July-August) means of the total O 3 derived from ground-based measurements taken at northern midlatitudes are analyzed for the period 1963-1999. We use a simple, multiple, linear regression model to examine the ozone changes related to interannual meteorological variability. The explanatory variables of the model are selected from many variables characterizing the atmospheric circulation in the troposphere, the lowermost stratosphere, and the stratospheric overworld. The modeled time series of the midwinter and summer total ozone over Europe and North America show significant year-to-year variations corresponding to observed variations. Moreover, the model reproduces correlation between the summer (June-July-August) midlatitudinal ozone and its preceding midwinter (January-February) value. The model calculates its lowest ozone amount during winter 1993. This follows the Mount Pinatubo eruption, but the ozone behavior can be explained as a result of dynamical variations only. The model-observation agreement provides support for the hypothesis that the long-term variations in total ozone over northern midlatitudes are strongly modulated by transport processes. It is estimated that interannual changes in the dynamical processes account for ∼70-80% of the long-term ozone decline over the northern midlatitudes for the 1970-1997 period.

The long-term variability of atmospheric ozone from the 50-yr observations carried out at Belsk (51.84°N, 20.78°E), Poland

Total ozone (TO3) and ozone vertical profile (by the Umkehr method) have been measured at Belsk (51.84°N, 20.78°E), Poland, since March 1963. The monthly mean data are analysed for the long-term changes in the period 1975–1996 and 1997–2012, that is, in the increasing and decreasing phases of the ozone-depleting substances (ODS) concentration in the mid-altitude stratosphere over the NH mid-latitudes. Standard explanatory variables are selected for the ozone variability attribution to chemical and dynamical processes. A triad of regression models with various formulae for the trend term is examined to get a synergetic effect. The trend term could be: (1) proportional to ODS, (2) piecewise linear (with the turning points in 1975 – the trend onset and in 1997 – the trend overturning), (3) represented by any smooth curve fitted to the ozone time series having ‘natural variations’ removed. Confirming the results from previous studies on the midlatitudinal ozone, the analyses show a weakening of the TO3 trend and the statistically significant positive trend in the upper stratospheric region (33–43 km) since 1997. The TO3 depletion in summer and autumn for the period 1997–2012 is found in the Umkehr data due to the ozone decrease in the lower and mid-stratosphere. A novel statistical-simulation-based test is proposed. It uses the bootstrap sample of the smooth trend pattern to calculate statistical significance of hypotheses for the trend variability. The test corroborates the results of the regression models and shows strengthening of the ozone negative trend in summer and autumn, disclosed in the Umkehr data, since about 2005.

The role of stratospheric minor warmings in producing the total ozone deficiencies over Europe in 1992 and 1993

Abstract During 1992 and 1993, record low total ozone values were observed over the middle and high northern latitudes. The ozone data from the long-operating station at Belsk, Poland, have been used to examine their departures from climatological behaviour in 1992 and 1993. It seems that not only do the exceptionally low ozone amounts recorded over the northern mid-latitudes need an explanation but also their occurrence for two years in a row. One of the possible mechanisms which may be responsible for this event is suggested to be connected with the occurrence of stratospheric minor warmings. They occur without a breakdown of the polar vortex but only with the displacement of very cold air towards lower latitudes (as in January 1992 and February 1993). It is known that air masses in the polar vortex have been chemically disturbed and, when they arrive over the sunlit middle latitudes, chemical destruction of ozone is likely to occur. During the periods under study, the strongest negative total ozone deviations correspond to strong negative temperature deviations at 30 hPa and to large potential vorticity values; this points to the presence over Europe of air masses of polar vortex origin. It has been shown that the characteristics of mid-winter stratospheric warmings and the interannual variability of winter-spring total ozone averages at Belsk are associated with each other.

24 hour forecast of the surface UV for the antipsoriatic heliotherapy in Poland.

Analyses of the spectral and broad-band UV data collected at Belsk (20.79°E, 51.84°N), Poland, show that standard broad-band instrument, Solar Light (SL) 501A, could be used for measurements of both erythemal and antipsoriatic irradiance. A prognostic model is proposed for the next-day duration of outdoor exposure required to receive a dose, the so-called minimum antipsoriatic dose (MAD), equivalent to that received by standard antipsoriatic daily treatment in the phototherapy cabinet containing TL-01 fluorescent tubes. The model uses the 24 h forecast of the column amount of ozone (to predict next day clear sky UV irradiance), and low- and mid-level cloudiness (to estimate a reduction of the clear-sky UV irradiation due to clouds). The predicted duration of sunbathing required to receive a dose of 1 MAD matches the observed value, i.e. the correlation coefficients is 0.68. If the model predicts the antipsoriatic exposure over 1 MAD threshold the observed dose will be also above this threshold in 91% of cases. Thus, the model could be used for planning the next-day outdoor exposure to clear psoriasis. Hourly resolved maps, starting from 6 am up to 1 pm (GMT), showing the duration of antipsoriatic exposure over Poland are made public. The model provides a tool for a psoriatic patient to find the sunbathing starting time and its duration, which has the same healing potential as a single indoor phototherapy session.

System for monitoring UV radiation level in phototherapy cabins in Poland.

Introduction Ultraviolet phototherapy (UVP) is widely used in dermatological practice for the treatment of various skin diseases. Numerous studies support its beneficial curing effectiveness; however, overexposure to ultraviolet radiation can cause adverse health effects, such as sunburn reaction, erythema response, cataract, skin aging, etc. For these reasons, it is of special importance to monitor performance of UVP cabins using a calibration system to evaluate the UV doses incident upon the patient. Material and methods A mechanized cabin control system (CCS) is proposed. It consists of radiometers with a wide and narrow field of view to estimate the body irradiation and to identify malfunctioning cabin tubes. Quality control and quality assurance procedures are developed to keep high accuracy of the calibration procedure. The CCS has been used in the examination of two different types of UVP cabins routinely working in Poland. Results It allows precise calculation of UV doses and spatial variability of UV radiance inside the cabin, thus providing uncertainties of the doses assigned by medical staff. The CCS could potentially serve as a primary standard for monitoring various UVP cabins working in Poland. Conclusions The methodology developed to quantify UV doses in UVP cabins may be easily extended to any UV radiation source.