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Dive into the research topics where Bora B. Mikic is active.

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Featured researches published by Bora B. Mikic.


Journal of Fluid Mechanics | 1986

Numerical investigation of incompressible flow in grooved channels. Part 1. Stability and self-sustained oscillations

Nesreen Ghaddar; K. Z. Korczak; Bora B. Mikic; Anthony T. Patera

Incompressible moderate-Reynolds-number flow in periodically grooved channels is investigated by direct numerical simulation using the spectral element method. For Reynolds numbers less than a critical value R c the flow is found to approach a stable steady state, comprising an ‘outer’ channel flow, a shear layer at the groove lip, and a weak re-circulating vortex in the groove proper. The linear stability of this flow is then analysed, and it is found that the least stable modes closely resemble Tollmien–Schlichting channel waves, forced by Kelvin–Helmholtz shear-layer instability at the cavity edge. A theory for frequency prediction based on the Orr–Sommerfeld dispersion relation is presented, and verified by variation of the geometric parameters of the problem. The accuracy of the theory, and the fact that it predicts many qualitative features of low-speed groove experiments, suggests that the frequency-selection process in these flows is largely governed by the outer, more stable flow (here a channel), in contrast to most current theories based solely on shear-layer considerations. The instability of the linear mode for R > R c is shown to result in self-sustained flow oscillations (at frequencies only slightly shifted from the originating linear modes), which again resemble (finite-amplitude) Tollmien-Schlichting modes driven by an unstable groove vortex sheet. Analysis of the amplitude dependence of the oscillations on degree of criticality reveals the transition to oscillatory flow to be a regular Hopf bifurcation.


Journal of Thermophysics and Heat Transfer | 1990

Numerical prediction of convective heat transfer in self-sustained oscillatory flows

Cristina H. Amon; Bora B. Mikic

Numerical investigations of the flow pattern and heat transfer enhancement in supercritical grooved-channel and communicating-channels flows are presented. For Reynolds numbers above the critical one, Rc =0(100), these flows exhibit laminar self-sustained oscillations at the plane channel Tollmien-Schlichting frequency. These ordered, very well-mixed flows require significantly less pumping power than the random fluctuating turbulent flows to achieve the same transport rates. Comparing different heat transfer augmentation schemes in grooved channels, it is shown that the best enhancement system regarding minimum power dissipation corresponds to passive flow modulation in the range of low Nusselt numbers. However, spontaneous supercritical flow destabilization becomes competitive as the Nusselt number is increased. It is found that on an equal pumping power basis, the heat transfer in communicating channels flows is up to 300% higher than the one in flat channel flow.


Journal of Biomedical Optics | 2003

Optoacoustic tomography using time-resolved interferometric detection of surface displacement.

Barry P. Payne; Vasan Venugopalan; Bora B. Mikic; Norman S. Nishioka

We introduce a minimally invasive technique for optoacoustic imaging of turbid media using optical interferometric detection of surface displacement produced by thermoelastic stress transients. The technique exploits endogenous or exogenous optical contrast of heterogeneous tissues and the low attenuation of stress wave propagation to localize and image subsurface absorbers in optically turbid media. We present a system that utilizes a time-resolved high-resolution interferometer capable of angstrom-level displacement resolution and nanosecond temporal resolution to detect subsurface blood vessels within model tissue phantoms and a human forearm in vivo.


Numerical Heat Transfer Part A-applications | 1991

Spectral element simulations of unsteady forced convective heat transfer; Application to compact heat exchanger geometries

Cristina H. Amon; Bora B. Mikic

Numerical investigations of the flow pattern and forced convective heat transfer in supercritical flows, such as those encountered in compact heat exchangers, are presented. These flows exhibit laminar self-sustained oscillations at the plane channel Tollmien-Schlichting frequency for Reynolds numbers above the critical one. These studies indicate that oscillatory separated flow results in large-scale convective patterns that are responsible for significant heat transfer enhancement and leads to a reduction in the pumping power required to achieve a given Nusselt number. The hydrodynamic-heat transfer numerical results are obtained by direct simulation of the unsteady energy and Navier-Stokes equations using a spectral element method for the spatial discretization. The spectral element method is a high-order weighted-residual technique that exploits both the common features and the competitive advantages of low-order finite element methods (versatility) and spectral techniques (accuracy and rapid converge...


Journal of Biomechanical Engineering-transactions of The Asme | 1994

the effect of laser parameters on the zone of thermal injury produced by laser ablation of biological tissue

Vasan Venugopalan; Norman S. Nishioka; Bora B. Mikic

A thermal model to predict the effect of laser parameters on the zone of thermal injury produced by laser ablation of biological tissue is presented. The model suggests that the Péclèt number based on the optical penetration depth of laser radiation is the key parameter in determining the resulting zone of thermal injury. We show that the zone of thermal injury is minimized for Péclèt numbers greater than one since the transport of energy via conduction beyond the ablation front is minimized. We also show that for Péclèt numbers less than one, larger zones of thermal damage are unavoidable regardless of the laser pulse duration. The predictions of the model are compared with data available in the literature. Deviations between the model predictions and published data are discussed and the potential effects of the model assumptions, optical scattering, pyrolysis, temporal pulse shape, pulse duration, irradiance and pulse repetition rate are explored.


Lasers in Surgery and Medicine | 1998

Comparison of pulsed CO2 laser ablation at 10.6 μm and 9.5 μm

Barry P. Payne; Norman S. Nishioka; Bora B. Mikic; Vasan Venugopalan

The pulsed CO2 laser has received attention because of its successful application to dermatologic surgery and burn debridement surgery. Despite impressive results, tissue removal using pulsed CO2 laser irradiation has not been optimized. We examined the ablation processes by performing mass removal and thermal injury experiments at wavelengths where tissue water is the primary absorber (10.6 μm), and where water and collagen have comparable absorption (9.5 μm).


Journal of Biomedical Optics | 2003

Optoacoustic determination of optical attenuation depth using interferometric detection

Barry P. Payne; Vasan Venugopalan; Bora B. Mikic; Norman S. Nishioka

We use a modified Mach-Zehnder interferometer to measure surface displacement resulting from the thermoelastic response of a target to the absorption of a short laser pulse with axial and temporal resolutions of 0.1 nm and 3 ns, respectively. These measurements are used in conjunction with a solution to the thermoelastic wave equation and a nonlinear optimization algorithm to extract optical attenuation depth. We demonstrate the ability to determine the effective optical attenuation depth of homogeneous targets with either diffuse or specular reflecting surfaces with a precision of <or=4% for attenuation depths spanning 0.1 to 2 mm.


Applied Optics | 1999

Measurement of tissue absorption coefficients by use of interferometric photothermal spectroscopy

Andrew D. Yablon; Norman S. Nishioka; Bora B. Mikic; Vasan Venugopalan

We describe a spectroscopic technique called interferometric photothermal spectroscopy (IPTS) that can measure the absorption coefficient of pulsed laser radiation in nonscattering tissue samples. The technique is suitable for measuring effective absorption coefficients from 10(3) to 10(5) cm(-1). IPTS is particularly attractive because it requires minimal disturbance of the sample. These features indicate potential use for in vivo measurements of tissue absorption coefficients. To validate the technique, the absorption coefficient of pulsed Q-switched Er:YSGG (2.79-microm) radiation in pure water was measured to be 5200 (+/-500) cm(-1) when IPTS was used, in agreement with other published values. IPTS was also used to measure the absorption coefficient of pulsed ArF excimer laser radiation (193 nm) in bovine corneal stroma (in vitro), giving a value of 1.9 (+/-0.4) x 10(4) cm(-1).


Heat Transfer Engineering | 1988

Temperature Prediction on Substrates and integrated Circuit Chips

E. J. Pinto; Bora B. Mikic

This work deals with application of semianalytical methods for evaluation of temperature distribution on substrates and integrated circuit chips. This approach is based on a method proposed by Hein and Lenzi in 1969 which is a combination of Fourier transform. Greens function, and surface-element methods. The application of the method has evolved from a model that predicts the steady-state temperature on one-layer structures with lead connectors (modeled as lumped thermal resistances) and planar-discrete sources to a model that includes the effects of multiple layers and anisotropic thermal conductivity. Further generalization of the method to three new cases is presented. The first includes the transient thermal behavior in the one-layer structures with planar-discrete sources and anisotropic conductivity. The second deals with the steady-periodic behavior of two-layer structures with planar-discrete-periodic sources and anisotropic conductivity. The third case solves for the steady-state temperature in...


Heat Transfer Engineering | 2003

Parametric investigation of viscous dissipation effects on optimized air cooling microchanneled heat sinks

Yoichi Murakami; Bora B. Mikic

The effects of viscous dissipation of working fluid on the optimum heat sink parameters are investigated for the case of air cooling with a micro-/narrow-channeled compact heat sink. For this purpose, an optimization method is introduced first on the basis of dimensionless groups while employing several assumptions. This method yields minimum pumping work or pressure drop with a set of optimized geometric/hydrodynamic parameters when outer dimension of a heat sink and imposed thermal load are specified. Especially for the case of laminar flow, the procedure presents an explicit existence of cooling limit by the viscous heat generation, giving an analytical expression of the maximum removable heat Q max . The relationships between thermal load and each parameter are calculated for both laminar and turbulent regimes under the conditions of compact heat sink dimension (20 mm 2 20 mm 2 2 mm) and circular cross-sectional shape of channels. The results show that the cooling capability under such conditions is largely limited by the salient manifestation of viscous dissipation, when compared with our previous investigation on water cooling presented in [1]. From the discussion, it was concluded that when a micro-/narrow-channeled heat sink is to be designed with air, the effect of viscous dissipation should be taken into account in order to avoid falling on wrong optimum solutions.

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Anthony T. Patera

Massachusetts Institute of Technology

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Nesreen Ghaddar

American University of Beirut

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Andrew D. Yablon

Massachusetts Institute of Technology

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Ioannis N. Miaoulis

Massachusetts Institute of Technology

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Yoichi Murakami

Tokyo Institute of Technology

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