Bora Özden

Prevalence and distribution of odontogenic and nonodontogenic cysts in a Turkish population

Objective: To determine the relative frequency and distribution of odontogenic and nonodontogenic cysts in a large Turkish population. Study Design A retrospective survey of jaw cysts was undertaken at the Oral Diagnosis and Radiology and Oral and Maxillofacial Surgery Department, Ondokuz Mayıs University Dental School, Samsun, Turkey. Data were retrieved from clinical files, imaging, and histopathology reports from 2000 to 2008; a total of 12,350 patients were included. In each case, we analyzed age, gender, type and number of cysts, and cyst location. Imaging patterns and pathologies associated with cystic lesions were also determined. Results: The prevalence of odontogenic and nonodontogenic cysts was 3.51%; males were affected more frequently than females. There were 452 odontogenic cysts (98.5%) and seven nonodontogenic cysts (1.5%). The most frequent odontogenic cyst was radicular (54.7%), followed by dentigerous (26.6%), residual (13.7%), odontogenic keratocyst (3.3%), and lateral periodontal cyst (0.2%). Nasopalatine duct cyst (1.5%) was the only nonodontogenic cyst. By age, cysts peaked in the third decade (24.2%). Concerning location, no statistically significant difference was found between the maxilla and mandible (p>0.05). The most frequent radiological feature of these lesions was unilocular cyst (93.7%). Pathologies associated with cystic lesions occurred in 14.7%. Conclusion: The prevalence of both odontogenic and nonodontogenic cysts were lower than that reported in many other studies. In our study population, cysts were mainly inflammatory in origin. Key words: Prevalence, odontogenic, nonodontogenic, cysts.

Intractable Bimaxillary Osteomyelitis in Osteopetrosis: Review of the Literature and Current Therapy

PURPOSE Osteopetrosis (OP), also known as Albers-Schönberg disease, is a rare metabolic bone disease caused by a congenital defect in the development or function of the osteoclasts resulting in generalized increase in skeletal mass. Osteomyelitis is a recognized complication, and prevention of dental infections can be difficult. The locations of osteomyelitis in the jawbones have been either in the mandible or maxilla. In this article, a case of OP complicated with osteomyelitis of the mandible and the maxilla is presented, and types of OP and treatment options are discussed with a literature review. MATERIALS AND METHODS The 18-year-old blind female patient had been diagnosed with OP in the past. She had a purulent discharge at the medial canthus of the left eye, in addition to another discharge of pus in the infraorbital and upper left molar region, and multiple malformed and partially impacted teeth, and there were sequestrum formations in the maxilla and mandible. For the treatment of osteomyelitis, systemic combined antibiotics of sultamicillin 750 mg and ornidazole 500 mg twice daily, were given orally for 5 weeks followed by surgical removal of small sequestra in the jaws. Persistent osteomyelitic bones were removed by saucerization in the mandibular anterior and right premolar region and the left posterior maxilla under the same antibiotic regimen. After wound healing was completely achieved in both jaws, the oroantral opening in the left posterior maxilla was successfully closed with a buccal flap under antibiotic coverage. RESULTS The purulent discharge at the medial canthus of her left eye subsided and she had no recurrent infections during the long-term follow-up of 2 years. CONCLUSION The case reported shows that osteomyelitis is difficult to treat in subjects suffering from OP. Therefore, it is necessary to be very cautious against infections in even minor surgical interventions such as simple dental extractions in patients with OP, regardless of the location of the teeth. When considering removal of impacted teeth in the posterior maxilla, resultant oroantral communication from osteomyelitis of the extraction site should be regarded as a potential complication.

A Case Report of Focal Epithelial Hyperplasia (Heck’s disease) with PCR Detection of Human Papillomavirus

Focal epithelial hyperplasia or Heck’s disease, is a rare viral infection of the oral mucosa caused by human papillomavirus. The frequency of this disease varies widely from one geographic region to another. In Caucasians there have been only few cases reported. This paper reports a case of focal epithelial hyperplasia and demonstrates the association with HPV subtype 32 through polymerase chain reaction (PCR) and sequencing of PCR products. A 7-year-old Caucasian girl was admitted to our clinic for investigation of multiple oral mucosal lesions in the mouth. Lesion was excised under local anesthesia without any complication. The lesion was diagnosed as focal epithelial hyperplasia according to both clinical and histopathological features. Dental staff should be aware of these kind of lesions and histopathological examination together with a careful clinical observation should be carried out for a definitive diagnosis.

Prevalence and characteristics of intracoronal resorption in unerupted teeth in the permanent dentition: a retrospective study

ObjectiveTo determine the prevalence, types of teeth, and distribution of intracoronal resorption in permanent dentition in a large population.MethodsA total of 9,570 panoramic radiographs were screened, and 2,922 unerupted teeth were examined.ResultsThe prevalence of intracoronal dentine defects was 1.55% in subjects and 0.95% in teeth. The highest prevalence of intracoronal radiolucencies was noted in the mandibular second molar (9.5%), followed by the maxillary second premolar tooth (4.7%). To our knowledge, this is the first report of coronal radiolucency in maxillary supernumerary teeth. Of the lesions identified, 39.3% were two-thirds of the dentine thickness, and 21.4% included the enamel; 85.7% of the defects were located at the central aspect of the crown. Ectopically positioned teeth showing intracoronal resorption accounted for 14.3% of the cases.ConclusionsIntracoronal resorption in an unerupted tooth occurs frequently and can be seen in more than one tooth in an individual. This condition is usually associated with not only an ectopic position but also resorption, which may be a progressive process. Dental clinicians should conduct periodic follow-ups, both clinical and radiographic, of these unerupted teeth.

Use of artificial neural network in differentiation of subgroups of temporomandibular internal derangements: a preliminary study.

PURPOSE Artificial neural networks (ANNs) have been developed in the past few decades for many different applications in medical science and in biomedical research. The use of neural networks in oral and maxillofacial surgery is limited. The aim of this study was to determine the use of ANNs for the prediction of 2 subgroups of temporomandibular joint (TMJ) internal derangements (IDs) and normal joints using characteristic clinical signs and symptoms of the diseases. MATERIALS AND METHODS Clinical symptoms and diagnoses of 161 patients with TMJ ID were considered the gold standard and were employed to train a neural network. After the training process, the symptoms and diagnoses of 58 new patients were used to verify the networks ability to diagnose. The diagnoses obtained from ANNs were compared with diagnoses of a surgeon experienced in temporomandibular disorders. The sensitivity and specificity of ANNs in predicting subtypes of TMJ ID were evaluated using clinical diagnosis as the gold standard. RESULTS Eight cases evaluated as bilaterally normal in clinical examination were evaluated as normal by ANN. In detecting unilateral anterior disc displacement with reduction (ADDwR; clicking), the sensitivity and specificity of ANN were 80% and 95%, respectively. In detecting unilateral anterior disc displacement without reduction (ADDwoR; locking), the sensitivity and specificity of ANN were 69% and 91%, respectively. In detecting bilateral ADDwoR, the sensitivity and specificity of ANN were 37% and 100%, respectively. In detecting bilateral ADDwR, the sensitivity and specificity of ANN were 100% and 89%, respectively. In detecting cases of ADDwR at 1 side and ADDwoR at the other side, the sensitivity and specificity of ANN were 44% and 93%, respectively. CONCLUSION The application of ANNs for diagnosis of subtypes of TMJ IDs may be a useful supportive diagnostic method, especially for dental practitioners. Further research, including advanced network models that use clinical data and radiographic images, is recommended.

Screw fixation is superior to N-butyl-2-cyanoacrylate in onlay grafting procedure: a histomorphologic study

The aim of this study is the histopathological evaluation of the efficiency of N-2-butyl cyanoacrylate in the fixation of bone block grafts on mandible. Autogenous monocortical block grafts taken from tibial bone were fixed to the outer surface of the angle of the mandible with N-2-butyl cyanoacrylate on the right side and mini screws on the left side. Postoperatively in the first and third months, six rabbits were killed and tissue samples were obtained from the grafted area. No significant difference was found between the cyanoacrylate and screw group with respect to inflammation or foreign body reaction. The level of graft necrosis was found to be significantly higher in the cyanoacrylate group than in the screw group in both the first and third month samples. Bone formation between the graft and recipient bone was evaluated and bone formation was found to be significantly higher in the screw group than in the cyanoacrylate group. No trabecular bone formation was observed between the graft and recipient bone in the cyanoacrylate group. Screw fixation was found to be superior to N-2-butyl cyanoacrylate in all parameters.

The multidisciplinary management of a fused maxillary central incisor with a talon cusp

BACKGROUND A fused maxillary incisor required complex multidisciplinary treatment to preserve health and restore aesthetics. This report presents a rare case of a dental fusion between the maxillary right central incisor and a supernumerary tooth of a 9-year-old male patient with the chief complaint of the presence of a large anterior tooth. METHODS Radiographic investigation and computerized tomography indicated there was no connection between pulp chambers. After dividing the crown with a diamond bur, the supernumerary tooth was removed and the diastema between the maxillary central incisors was closed by orthodontic treatment. The tooth was then restored with composite resin. RESULTS The maxillary right central incisor was still healthy after a follow-up examination period of 24 months. CONCLUSIONS A multidisciplinary approach with the cooperation of different practitioners can contribute to the success of a treatment plan.

Diagnosis of periodontal diseases using different classification algorithms: a preliminary study.

OBJECTIVE The purpose of the proposed study was to develop an identification unit for classifying periodontal diseases using support vector machine (SVM), decision tree (DT), and artificial neural networks (ANNs). MATERIALS AND METHODS A total of 150 patients was divided into two groups such as training (100) and testing (50). The codes created for risk factors, periodontal data, and radiographically bone loss were formed as a matrix structure and regarded as inputs for the classification unit. A total of six periodontal conditions was the outputs of the classification unit. The accuracy of the suggested methods was compared according to their resolution and working time. RESULTS DT and SVM were best to classify the periodontal diseases with a high accuracy according to the clinical research based on 150 patients. The performances of SVM and DT were found 98% with total computational time of 19.91 and 7.00 s, respectively. ANN had the worst correlation between input and output variable, and its performance was calculated as 46%. CONCLUSIONS SVM and DT appeared to be sufficiently complex to reflect all the factors associated with the periodontal status, simple enough to be understandable and practical as a decision-making aid for prediction of periodontal disease.

Descending necrotizing mediastinitis associated with an infected dentigerous cyst

Descending necrotizing mediastinitis (DNM) is a rare condition in which an infection from the head and neck propagates into the mediastinum. The most common cause of DNM is odontogenic infection. DNM is spread by the fascial planes from the neck into the mediastinum and requires an aggressive surgical drainage through cervical and thoracic approaches. We report on a 67-year-old male patient, who had acute mediastinitis related to an infected dentigerous cyst in the left parasymphyseal region. A multidisciplinary team approach was used to treat the patient. The team consisted of thoracic surgeons, maxillofacial surgeons, and a radiologist. After the drainage of the mediastinum and pleural cavity, the cyst was enucleated. The patient was discharged at the 42nd day of hospitalization. The aim of this article is to present diagnosis, management, and follow-up of an infected dentigerous cyst that caused DNM.

Could Calcified Triglyceride Bone Cement Be an Alternative Graft Material in Maxillary Sinus Augmentation

Abstract The ideal graft material for maxillary sinus augmentation is still a matter of controversy and the search for a more appropriate bone substitute for use continues. The aim of this study was to evaluate bone formation as a sign of the regeneration following maxillary sinus augmentation in rabbits using 3 different biomaterials, one of which is a newly developed graft material; calcified triglyceride bone cement (CTBC). Twenty-one New Zealand rabbits were used and randomly divided into 3 groups. Bilateral maxillary sinus augmentation was carried out and autogenous bone (AB), bovine hydroxyapatite (BHA), and CTBC were administered. Maxillary sinuses were dissected after fourth and eighth weeks of the operation. The bone formation was evaluated by stereological and histopathological analysis and the data were analyzed statistically. When the volume of primary bone is compared, statistically significant differences were found among all groups at both of the fourth and eighth weeks. The highest value was obtained from AB applied group. In BHA and CTBC applied groups, active bone formation, osseointegration of graft materials were observed at both fourth and eighth weeks. In CTBC applied group, primary bone formation was only seen as linked to the continuation of parent sinus bony wall. The efficiency of primary bone formation of CTBC was found less than AB and BHA. Of the 3 graft materials tested, BHA is the strongest alternative to AB graft for maxillary sinus augmentation.