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Dive into the research topics where Boris A. Zelle is active.

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Featured researches published by Boris A. Zelle.


Journal of Orthopaedic Trauma | 2005

Treatment of acute midshaft clavicle fractures Systematic review of 2144 fractures : On behalf of the evidence-based orthopaedic trauma working group

Michael Zlowodzki; Boris A. Zelle; Peter A. Cole; Kyle J. Jeray; Michael D. McKee

Background: Fractures of the clavicle were reported to represent 2.6% of all fractures1 with an overall incidence of 64 per 100,000 per year (1987, Malmö, Sweden).2 Midshaft fractures account for approximately 69% to 81% of all clavicle fractures.1-4 Treatment options for acute midshaft clavicle fractures include nonoperative treatment (mostly sling or figure-of-eight bandage), open reduction and internal fixation with plates, and closed or open reduction and internal fixation with intramedullary pins, wires, or a nail. Most surgeons prefer nonoperative treatment of nondisplaced midshaft clavicle fractures. However, the optimal treatment option for isolated acute displaced midshaft clavicle fractures remains controversial. Objectives: This study was designed to systematically summarize and compare results of different treatment options (nonoperative, operative extramedullary fixation, and operative intramedullary fixation) in the management of midshaft clavicle fractures, specifically for displaced fractures.


Journal of Orthopaedic Trauma | 2006

Treatment of distal tibia fractures without articular involvement : A systematic review of 1125 fractures

Boris A. Zelle; Mohit Bhandari; Michael Espiritu; Kenneth J. Koval; Michael Zlowodzki

The management of unstable distal tibia fractures remains challenging. The mechanism of injury and the prognosis of these fractures are different from pilon fractures, but their proximity to the ankle makes the surgical treatment more complicated than the treatment tibial midshaft fractures. A variety of treatment methods have been suggested for these injuries, including nonoperative treatment, external fixation, intramedullary nailing, and plate fixation. However, each of these treatment options is associated with certain challenges. Nonoperative treatment may be complicated by loss of reduction and subsequent malunion. Similarly, external fixation of distal tibia fractures may result in insufficient reduction, malunion, and pin tract infection. Intramedullary nailing can be considered the “gold standard” for the treatment of tibial midshaft fractures, but there are concerns about their use in distal tibia fractures. This is because of technical difficulties with distal nail fixation, the risk of nail propagation into the ankle joint, and the discrepancy between the diaphyseal and metaphyseal diameter of the intramedullary canal. Open reduction and internal plate fixation results in extensive soft tissue dissection and may be associated with wound complications and infections. The optimal treatment of unstable distal tibia without articular involvement remains controversial. Objectives: This study was designed to review the outcomes of different treatment methods for extra-articular distal tibia fractures. The English literature was systematically reviewed and the rates of malunion, nonunion, infection, fixation failure, and secondary surgical procedures were extracted.


Clinical Orthopaedics and Related Research | 2007

Intraarticular rupture pattern of the ACL.

Thore Zantop; Peter U. Brucker; Armando F. Vidal; Boris A. Zelle; Freddie H. Fu

To date, the intraarticular rupture pattern of the anterior cruciate ligament (ACL) has not been reported. The ACL is a complex structure consisting of two functionally synergistic structures: the anteromedial (AM) and posterolateral (PL) bundle. The purpose of our study was to evaluate the intraarticular rupture pattern of the ACL with regard to its two functional bundles. We examined ACL rupture patterns with regard to the integrity of AM and PL bundle in 121 consecutive patients undergoing anterior cruciate ligament reconstruction surgery within 120 days after injury. The intraarticular pattern was observed by one experienced surgeon. In 25% of the patients a partial rupture of the ACL was found, whereas in the remaining 75% a complete rupture of AM and PL bundles was seen. A partial rupture could only be detected by careful dissection of the ligament. In 44% of all patients the AM and PL bundles did not rupture at the same location. In 12% of the patients the PL bundle showed no signs of rupture. When performing ACL reconstruction, care should be taken when dissecting down the ACL remnants to evaluate intact fiber bundles of the ACL.Level of Evidence: Level IV, diagnostic study. See Guidelines for Authors for a complete description of levels of evidence.


Sports Medicine | 2006

Anatomical Double-Bundle Anterior Cruciate Ligament Reconstruction

Boris A. Zelle; Peter U. Brucker; Matthew T. Feng; Freddie H. Fu

A careful review of the literature suggests that a significant number of patients undergoing anterior cruciate ligament (ACL) reconstruction have less than optimal results. Although overall outcomes of ACL reconstruction are favourable, there remains considerable room for improvement. Anatomically, the ACL consists of two major functional bundles, the anteromedial and the posterolateral bundle. Biomechanically, both bundles contribute significantly to the anterior and the rotational stability of the knee. Therefore, anatomical double-bundle ACL reconstruction techniques may further improve the outcomes in ACL surgery. Our preferred technique for arthroscopic double-bundle ACL reconstruction includes the use of two femoral and two tibial tunnels to restore both the anteromedial and the posterolateral bundle of the ACL and their anatomical footprints at their tibial and femoral insertion site. We use two tibialis anterior tendon allografts for the restoration of the two ACL bundles. Clinical long-term outcome studies may focus on the evaluation of functional outcomes, restoration of anterior and rotational knee stability, and the risk of degenerative osteoarthritis of the knee joint following anatomical double-bundle ACL reconstruction versus single-bundle ACL reconstruction.


Journal of Orthopaedic Trauma | 2006

Treatment of scapula fractures : Systematic review of 520 fractures in 22 case series

Michael Zlowodzki; Mohit Bhandari; Boris A. Zelle; Philip J. Kregor; Peter A. Cole

Background Fractures of the scapula account for 3% to 5% of all fractures of the shoulder girdle39–41 and make up less than 1% of all broken bones.42 Scapula fractures typically occur after high-energy trauma, and approximately 90% of the patients have associated injuries.39,43 Objective (1) To determine the incidences of nonoperative and operative treatment of different scapula fracture types, (2) to systematically stratify the reported results of nonoperatively and operatively treated scapula fractures on the basis of different fracture types and to summarize functional results, and (3) to quantify infection and secondary surgical procedure rates after operative treatment.


Journal of Bone and Joint Surgery, American Volume | 2005

Reamed femoral nailing in sheep: does irrigation and aspiration of intramedullary contents alter the systemic response?

Hans Christoph Pape; Boris A. Zelle; Frank Hildebrand; Peter V. Giannoudis; Christian Krettek; Martijn van Griensven

BACKGROUND Reaming of the femoral canal has been demonstrated to introduce intramedullary contents into the circulation with subsequent pulmonary embolization. The aim of this study was to investigate whether this effect can be minimized by use of a reamer system that provides simultaneous irrigation and aspiration of intramedullary contents. METHODS A unilateral lung contusion was created and intramedullary femoral nailing was subsequently performed in eighteen female skeletally mature Merino sheep. The animals were divided into three groups, of six animals each, to receive one of three types of treatment: reamed femoral nailing; reaming, irrigation, and aspiration; and unreamed femoral nailing. Blood samples were obtained and a bronchoalveolar lavage was performed at baseline, immediately after creation of the lung contusion, immediately after intramedullary nailing, and at four hours after surgery. Pulmonary permeability, polymorphonuclear leukocyte activity, and systemic hemostatic response were measured. Lung specimens were obtained for histological evaluation. RESULTS At baseline and immediately after creation of the lung contusion, endothelial permeability was comparable among the three groups. At four hours postoperatively, pulmonary permeability was significantly higher in the group treated with reamed femoral nailing (urea/protein ratio; 256.7) than in the group treated with reaming, irrigation, and aspiration (urea/protein ratio, 91.5) and the group treated with unreamed femoral nailing (urea/protein, 110.64) (p < 0.05). The stimulatory capacity of the polymorphonuclear leukocytes was significantly decreased (p < 0.05) only in the group treated with reamed femoral nailing; the other two groups had no significant decrease postoperatively (p > 0.05). The D-dimer level at four hours postoperatively was significantly higher in the group treated with reamed femoral nailing than it was in the other two groups (p < 0.05). Histological examination showed that the grades of edema and polymorphonuclear leukocyte diapedesis were also highest in the group treated with reamed femoral nailing. CONCLUSIONS It appears that, in the presence of a unilateral pulmonary injury, the systemic effects of intramedullary reaming of an intact femur can be minimized with use of a modified reamer design that simultaneously irrigates the canal and removes debris. Additional clinical validation of this reaming system is necessary.


Journal of The American Academy of Orthopaedic Surgeons | 2007

Double-bundle reconstruction of the anterior cruciate ligament: anatomic and biomechanical rationale.

Boris A. Zelle; Armando F. Vidal; Peter U. Brucker; Freddie H. Fu

Abstract Patients continue to suffer residual pain and instability following anterior cruciate ligament reconstruction. Although overall outcomes of anterior cruciate ligament reconstruction are favorable, improved outcomes can be achieved. Recent biomechanical studies have questioned the ability of conventional single‐bundle anterior cruciate ligament constructs to adequately restore normal knee kinematics. Consequently, the use of doublebundle anterior cruciate ligament constructs has been recommended to restore knee stability more effectively. Recent biomechanical data indicate that double‐bundle anterior cruciate ligament reconstruction may provide better anteroposterior and rotational knee stability than do conventional single‐bundle techniques. Studies are needed to evaluate the clinical impact of double‐bundle reconstruction techniques on long‐term functional outcomes.


The Clinical Journal of Pain | 2005

Sacroiliac Joint Dysfunction: Evaluation and Management

Boris A. Zelle; Gary S. Gruen; Shervondalonn Brown; Susan E. George

Sacroiliac joint dysfunction is believed to be a significant source of low back and posterior pelvic pain. Methods:To assess the clinical presentation, diagnostic testing, and treatment options for sacroiliac joint dysfunction, a systematic literature review was performed using MEDLINE. Results:Presently, there are no widely accepted guidelines in the literature for the diagnosis and treatment of sacroiliac instability. Establishing management guidelines for this disorder has been complicated by the large spectrum of different etiologic factors, the variability of patient history and clinical symptoms, limited availability of objective testing, and incomplete understanding of the biomechanics of the sacroiliac joint. Conclusions:A reliable examination technique to identify the sacroiliac joint as a source of low back pain seems to be pain relief following a radiologically guided injection of a local anaesthetic into the sacroiliac joint. Most patients respond to non-operative treatment. Patients who do not respond to non-operative treatment should be considered for operative sacroiliac joint stabilization.


Journal of Orthopaedic Trauma | 2010

Extracorporeal shock wave therapy: current evidence.

Boris A. Zelle; Hans Gollwitzer; Michael Zlowodzki; V. Bühren

Objectives: The aim of this article is to provide a concise review of the basic science of extracorporeal shock wave therapy (ESWT) and to perform a systematic review of the literature for the use of ESWT in the treatment of fractures and delayed unions/nonunions. Data Sources: Articles in the English or German language were identified for the systematic review by searching PubMed-MEDLINE from 1966 until 2008, Cochrane Database of Systematic Reviews, Cochrane Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, and relevant meeting abstracts from 2007 to 2008. Moreover, the bibliographies of the identified articles were reviewed. Study Selection: We included clinical outcome studies of ESWT in the treatment of fractures and delayed unions/nonunions. Reports with less than 10 patients were excluded. Nonunions after corrective osteotomies or arthrodeses were excluded. Data Extraction: Sample size, level of evidence, definition of delayed union, definition of nonunion, time from injury to shock wave treatment, location of fracture, union rate, and complications were extracted from the identified articles. Data Synthesis: Data of 924 patients undergoing ESWT for delayed union/nonunion were extracted from 10 studies. All articles were graded as level 4 studies. The overall union rate was 76% (95% confidence interval 73%-79%). The union rate was significantly higher in hypertrophic nonunions than in atrophic nonunions. Conclusion: Data from level 4 studies suggest that shock wave therapy seems to stimulate the healing process in delayed unions/nonunions. However, further investigations are required.


International Orthopaedics | 2004

Sacral fractures with neurological injury: is early decompression beneficial?

Boris A. Zelle; Gary S. Gruen; T. Hunt; S. R. Speth

During a 6-year period, 177 patients with a displaced sacral fracture were treated at our level-one trauma centre. At the initial presentation, 13 patients demonstrated a neurological deficit as a result of their sacral fracture. Six patients underwent surgical decompression, and seven patients were managed without surgical decompression. All patients were re-assessed at an average follow-up of 27.1 (range 12–84) months using the modified SOFCOT Index and the SF-36. Patients undergoing surgical decompression had a significantly better neurological improvement as measured by the modified SOFCOT Index (p=0.014). Moreover, patients undergoing surgical decompression had a significantly better physical function than the patients that were managed without surgical decompression, as measured by the SF-36 (p=0.044). We therefore believe that patients undergoing surgical decompression achieve better neurological improvement and better functional results.RésuméPendant une période de six années, 177 malades avec une fracture déplacée du sacrum ont été traités à notre centre de trauma (niveau un). À la présentation initiale, 13 malades avaient un déficit neurologique suite à leur fracture sacrée. Six malades ont subi une décompression chirurgicale, et sept malades ont été traités sans décompression. Tous les malades étaient revus avec un délai moyen de 27,1 mois ( 12 à 84) en utilisant l’index SOFCOT modifié et le SF-36. Les malades qui avaient eu une décompression chirurgicale avaient une amélioration neurologique notablement meilleure selon l’index SOFCOT modifié (p=0.014) et une meilleure fonction quotidienne, comme mesuré par le SF-36 (p=0.044). Nous croyons par conséquent que les malades qui subissent une décompression chirurgicale ont de meilleurs résultats.

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Freddie H. Fu

University of Pittsburgh

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C. Krettek

Hannover Medical School

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Gary S. Gruen

University of Pittsburgh

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