Bradley D. Freeman | Researchain

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Featured researches published by Bradley D. Freeman.

Critical Care Medicine | 2001

A prospective, randomized study comparing percutaneous with surgical tracheostomy in critically ill patients

Bradley D. Freeman; Karen Isabella; J. Perren Cobb; Walter A. Boyle; Robert E. Schmieg; Marin H. Kolleff; Natatia Lin; Thomas Saak; Errington C. Thompson; Timothy G. Buchman

ObjectiveTo determine the relative cost-effectiveness of percutaneous dilational tracheostomy (PDT) and surgical tracheostomy (ST) in critically ill patients. DesignProspective randomized study. SettingMedical, surgical, and coronary intensive care units at Barnes-Jewish Hospital, a tertiary care medical center. PatientsEighty critically ill mechanically ventilated patients requiring elective tracheostomy. InterventionsRandomization to either PDT performed in the intensive care unit or ST performed in the operating room. Measurements and Main Results Treatment groups were well matched with respect to age (PDT, 65.44 ± 2.82 [mean ± se] years; ST, 61.4 ± 2.89 years, p = Ns), gender (PDT, 45% males; ST, 47.5% males, p = NS), severity of illness (Acute Physiology and Chronic Health Evaluation II score: PDT, 16.87 ± 0.84; ST, 17.88 ± 0.92, p = NS), and principle diagnosis. PDT was performed more quickly (PDT, 20.1 ± 2.0 mins; ST, 41.7 ± 3.9 mins, p < .0001) and was associated with lower patient charges than ST (total patient charges: PDT,

Critical Care Medicine | 2000

Rapid onset of intestinal epithelial and lymphocyte apoptotic cell death in patients with trauma and shock.

Richard S. Hotchkiss; Robert E. Schmieg; Paul E. Swanson; Bradley D. Freeman; Kevin W. Tinsley; Cobb Jp; Irene E. Karl; Timothy G. Buchman

1,569 ±

Molecular & Cellular Proteomics | 2006

High Dynamic Range Characterization of the Trauma Patient Plasma Proteome

Tao Liu; Wei Jun Qiant; Marina A. Gritsenko; Wenzhong Xiao; Lyle L. Moldawer; Amit Kaushal; Matthew E. Monroe; Susan M. Varnum; Ronald J. Moore; Samuel O. Purvine; Ronald V. Maier; Ronald W. Davis; Ronald G. Tompkins; David G. Camp; Richard D. Smith; Henry V. Baker; Paul E. Bankey; Timothy R. Billiar; Bernard H. Brownstein; Steve E. Calvano; Celeste Campbell-Finnerty; George Casella; Irshad H. Chaudry; Mashkoor A. Choudhry; J. Perren Cobb; Asit De; Constance Elson; Bradley D. Freeman; Richard L. Gamelli; Nicole S. Gibran

157 vs. ST,

Critical Care Medicine | 2005

Relationship between tracheostomy timing and duration of mechanical ventilation in critically ill patients

Bradley D. Freeman; Ingrid B. Borecki; Craig M. Coopersmith; Timothy G. Buchman

3,172 ±

Expert Opinion on Investigational Drugs | 2000

Anti-inflammatory therapies in sepsis and septic shock.

Bradley D. Freeman; Charles Natanson

114; equipment/supply charges: PDT,

Proceedings of the National Academy of Sciences of the United States of America | 2006

Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways.

Krzysztof Laudanski; Carol Miller-Graziano; Wenzhong Xiao; Michael Mindrinos; Daniel R. Richards; Asit De; Lyle L. Moldawer; Ronald V. Maier; Paul E. Bankey; Henry V. Baker; Bernard H. Brownstein; J. Perren Cobb; Steve E. Galvano; Ronald W. Davis; Ronald G. Tompkins; Timothy R. Billiar; David G. Camp; Celeste Campbell-Finnerty; George Casella; Irshad H. Chaudry; Mashkoor A. Choudhry; Constance Elson; Bradley D. Freeman; Richard L. Gamelli; Nicole S. Gibran; Brian G. Harbrecht; Douglas Hayden; David N. Herndon; Jureta W. Horton; William J. Hubbard

688 ±

Journal of The American College of Surgeons | 2002