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Dive into the research topics where Brett D. Crist is active.

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Featured researches published by Brett D. Crist.


Geriatric Orthopaedic Surgery & Rehabilitation | 2013

Comanagement of geriatric patients with hip fractures: a retrospective, controlled, cohort study.

Gregory J. Della Rocca; Kyle Moylan; Brett D. Crist; David A. Volgas; James P. Stannard; David R. Mehr

The objective of this 3-year retrospective, controlled, cohort study is to characterize an interdisciplinary method of managing geriatric patients with hip fracture. All patients aged 65 years or older admitted to a single academic level I trauma center during a 3-year period with an isolated hip fracture were included as participants for this study. Thirty-one geriatric patients with hip fracture were treated with historical methods of care (cohort 1). The comparison group of 115 similar patients was treated under a newly developed, institutional comanagement hip fracture protocol (cohort 2). There were no differences in age, sex distribution, or comorbidity distribution between the 2 cohorts. Patients requiring intensive care unit (ICU) admission decreased significantly from 48% in cohort 1 to 23% in cohort 2 (P = .0091). Length of ICU stay for patients requiring ICU admission also decreased significantly, from a mean of 8.1 days in cohort 1 to 1.8 days in cohort 2 (P = .024). Total hospital stay decreased significantly, from a mean of 9.9 days in cohort 1 to 7.1 days in cohort 2 (P = .021). Although no decrease in in-hospital mortality rates was noted from cohort 1 to cohort 2, a trend toward decreased 1-year mortality rates was seen after implementation of the hip fracture protocol. Hospital charges decreased significantly, from US


Journal of Orthopaedic Trauma | 2010

Complications Associated With Negative Pressure Reaming for Harvesting Autologous Bone Graft: A Case Series

Jason A. Lowe; Gregory J. Della Rocca; Yvonne M. Murtha; Frank A. Liporace; Michael D. Stover; Sean E. Nork; Brett D. Crist

52 323 per patient in cohort 1 to US


Journal of The American Academy of Orthopaedic Surgeons | 2011

Pilon fractures: advances in surgical management.

Brett D. Crist; Michael Khazzam; Murtha Ym; Della Rocca Gj

38 586 in cohort 2 (P = .0183). Implementation of a comanagement protocol for care of geriatric patients with hip fracture, consisting of admission to a geriatric primary care service, standardized perioperative assessment regimens, expeditious surgical treatment, and continued primary geriatric care postoperatively, resulted in reductions in lengths of stay, ICU admissions, and hospital costs per patient. On an annualized basis, this represented a savings of over US


Journal of The American Academy of Orthopaedic Surgeons | 2006

External Fixation Versus Conversion to Intramedullary Nailing for Definitive Management of Closed Fractures of the Femoral and Tibial Shaft

Gregory J. Della Rocca; Brett D. Crist

700 000 for our institution.


Orthopedic Clinics of North America | 2010

Optimal treatment of femoral neck fractures according to patient's physiologic age: an evidence-based review.

Jason A. Lowe; Brett D. Crist; Mohit Bhandari; Tania A. Ferguson

A technical benefit of the reamer-irrigator-aspirator (RIA) system (Synthes, Paoli, PA) is the ability to harvest large volumes (40-90 cm3) of autogenous bone graft. Early evaluations of this technique have reported few problems, all of which were attributed to technical error. This case series reviews 6 RIA-associated complications including 4 fractures and their contributing risk factors. Cases were collected from 4 independent orthopaedic centers, and all patients underwent RIA bone graft harvesting in a lower extremity long bone injuries. In this population, 2 patients experienced acute RIA-associated events, necessitating an additional procedure or altered postoperative rehabilitation, whereas 4 patients fractured through their donor site in the early postoperative period. This series suggests that surgeons should (1) preoperatively assess cortical diameters at long bone harvest sites, (2) carefully monitor intraoperative reaming, and (3) avoid RIA bone graft harvesting in patients with a history of osteoporosis or osteopenia unless postharvest intramedullary stabilization is considered.


Wiley Interdisciplinary Reviews-nanomedicine and Nanobiotechnology | 2014

Coatings and surface modifications imparting antimicrobial activity to orthopedic implants

Roli Kargupta; Sangho Bok; Charles M. Darr; Brett D. Crist; Keshab Gangopadhyay; Shubhra Gangopadhyay; Shramik Sengupta

&NA; Pilon fractures are challenging to manage because of the complexity of the injury pattern and the risk of significant complications. Variables such as fracture pattern, soft‐tissue injury, and preexisting patient factors can lead to unpredictable outcomes. Avoiding complications associated with the soft‐tissue envelope is paramount to optimizing outcomes. In persons with soft‐tissue compromise, the use of temporary external fixation and staged management is helpful in reducing further injury and complications. Evidence in support of new surgical approaches and minimally invasive techniques is incomplete. Soft‐tissue management, such as negative‐pressure dressings, may be helpful in preventing complications.


Journal of Orthopaedic Trauma | 2011

Pitfalls in the application of distal femur plates for fractures.

Cory Collinge; Michael J. Gardner; Brett D. Crist

&NA; External fixation for definitive therapy of closed diaphyseal femur and tibia fractures is the preferred method of treatment only in the pediatric population. In adult injuries, in particular open battle wounds, the timing of conversion of an external fixator to an intramedullary nail is determined by the condition of the soft tissues and the overall stability of the patient. In the tibia, conversion to an intramedullary nail is accomplished as expeditiously as possible. Early (<2 weeks) conversion to an intramedullary implant may be accomplished safely. Increased infection rates have been documented when conversion is done after 2 weeks of external fixation. In the femur, conversion from external fixation to nailing is done as the patients overall physical condition and soft tissues allow. Acute conversion to an intramedullary device in a single procedure is preferred in patients without evidence of pin‐tract infection. Staged conversion to an intramedullary nail often requires a prolonged period of bed rest with skeletal traction to maintain fracture stability and patient comfort, with the attendant risks of pneumonia, decubiti, and thromboembolic events. Treatment of closed femoral and tibial diaphyseal fractures with external fixation, either definitively or as a bridge to intramedullary nailing, is a viable option in the patient with gross physiologic instability or an ipsilateral dysvascular limb. The decision to use definitive external fixation versus conversion to an intramedullary device should be made on a case‐by‐case basis. Additional prospective clinical studies are warranted to further delineate risks and benefits of these treatment modalities.


Journal of Applied Physiology | 2012

Acute impact of intermittent pneumatic leg compression frequency on limb hemodynamics, vascular function, and skeletal muscle gene expression in humans

Ryan D. Sheldon; Bruno T. Roseguini; John P. Thyfault; Brett D. Crist; M. H. Laughlin; Sean C. Newcomer

For decades, the basic tenets of managing displaced femoral neck fractures have not changed, but the optimal treatment choice continues to be highly debated. The contemporary controversies associated with the treatment principles of displaced femoral neck fractures are distinct between young and old patients and are considered individually in this article about the current evidence. Although fixation constructs all seem to have similar complication rates, there is increasing evidence suggesting that total hip replacement improves patient functional outcomes for healthy, independent, elderly patients compared with hemiarthroplasty and should be considered as the treatment of choice for these patients.


Journal of Arthroplasty | 2014

Improved Radiographic Outcomes With Patient-Specific Total Knee Arthroplasty

Conrad B. Ivie; Patrick J. Probst; Amrit K. Bal; James T. Stannard; Brett D. Crist; B. Sonny Bal

Bacterial colonization and biofilm formation on an orthopedic implant surface is one of the worst possible outcomes of orthopedic intervention in terms of both patient prognosis and healthcare costs. Making the problem even more vexing is the fact that infections are often caused by events beyond the control of the operating surgeon and may manifest weeks to months after the initial surgery. Herein, we review the costs and consequences of implant infection as well as the methods of prevention and management. In particular, we focus on coatings and other forms of implant surface modification in a manner that imparts some antimicrobial benefit to the implant device. Such coatings can be classified generally based on their mode of action: surface adhesion prevention, bactericidal, antimicrobial-eluting, osseointegration promotion, and combinations of the above. Despite several advances in the efficacy of these antimicrobial methods, a remaining major challenge is ensuring retention of the antimicrobial activity over a period of months to years postoperation, an issue that has so far been inadequately addressed. Finally, we provide an overview of additional figures of merit that will determine whether a given antimicrobial surface modification warrants adoption for clinical use.


Journal of Bone and Joint Surgery, American Volume | 2012

Surgical Timing of Treating Injured Extremities

Brett D. Crist; Tania A. Ferguson; Yvonne M. Murtha; Mark A. Lee

Despite design features intended to aid the surgeon in restoring proper alignment, malunion and implant-related problems are relatively common after a distal femur fracture treated with plate fixation. This article presents case examples of these problems followed by a discussion of the relevant distal femoral anatomy, design features of modern locked distal femur plating systems, and technical points necessary to avoid malunion and implant-related problems when using these devices.

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David A. Volgas

University of Alabama at Birmingham

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Michael Khazzam

University of Texas Southwestern Medical Center

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