Brian Chan

The average cost of pressure ulcer management in a community dwelling spinal cord injury population

Pressure ulcers (PUs) are a common secondary complication experienced by community dwelling individuals with spinal cord injury (SCI). There is a paucity of literature on the health economic impact of PU in SCI population from a societal perspective. The objective of this study was to determine the resource use and costs in 2010 Canadian dollars of a community dwelling SCI individual experiencing a PU from a societal perspective. A non‐comparative cost analysis was conducted on a cohort of community dwelling SCI individuals from Ontario, Canada. Medical resource use was recorded over the study period. Unit costs associated with these resources were collected from publicly available sources and published literature. Average monthly cost was calculated based on 7‐month follow‐up. Costs were stratified by age, PU history, severity level, location of SCI, duration of current PU and PU surface area. Sensitivity analyses were also carried out. Among the 12 study participants, total average monthly cost per community dwelling SCI individual with a PU was

Work-Related Lost Productivity and Its Economic Impact on Canadian Patients with Moderate to Severe Psoriasis

4745. Hospital admission costs represented the greatest percentage of the total cost (62%). Sensitivity analysis showed that the total average monthly costs were most sensitive to variations in hospitalisation costs.

Screening and prevention of venous thromboembolism in critically ill patients: a decision analysis and economic evaluation.

Background: Psoriasis impacts many different areas of a patients life, including work productivity. There is no information regarding lost productivity owing to psoriasis in a Canadian population. Objective: The objective of this study was to determine the lost productivity of Canadian patients with moderate to severe psoriasis. Methods: Seventy-nine consecutive Canadian dermatology patients were interviewed and completed the Work Productivity and Activity Impairment Questionnaire (WPAIQ). Results: On average, 2.2 hours (± 5.6 hours) were lost from work per week owing to psoriasis-related events. Absence from work may result in lost mean patient wages of C

Cost-effectiveness of Dalteparin vs Unfractionated Heparin for the Prevention of Venous Thromboembolism in Critically Ill Patients

2,270.84 per person per year. Total lost wages owing to moderate to severe psoriasis may cost up to approximately

Effect of Intravenous Immunoglobulin on Prednisone Dose in Patients with Pemphigus Vulgaris

749 million for all moderate to severe psoriasis patients in Canada. Conclusion: The results from our study indicate that moderate to severe psoriasis may have a substantial impact on the work productivity of patients with this disease.

Economic evaluation of the prophylaxis for thromboembolism in critical care trial (E-PROTECT): study protocol for a randomized controlled trial

RATIONALE Venous thromboembolism is difficult to diagnose in critically ill patients and may increase morbidity and mortality. OBJECTIVES To evaluate the cost-effectiveness of strategies to reduce morbidity from venous thromboembolism in critically ill patients. METHODS A Markov decision analytic model to compare weekly compression ultrasound screening (screening) plus investigation for clinically suspected deep vein thrombosis (DVT) (case finding) versus case finding alone; and a hypothetical program to increase adherence to DVT prevention. Probabilities were derived from a systematic review of venous thromboembolism in medical-surgical intensive care unit patients. Costs (in 2010

A scoping review on health economics in neurosurgery for acute spine trauma

US) were obtained from hospitals in Canada, Australia, and the United States, and the medical literature. Analyses were conducted from a societal perspective over a lifetime horizon. Outcomes included costs, quality-adjusted life-years (QALY), and incremental cost-effectiveness ratios. MEASUREMENTS AND MAIN RESULTS In the base case, the rate of proximal DVT was 85 per 1,000 patients. Screening resulted in three fewer pulmonary emboli than case-finding alone but also two additional bleeding episodes, and cost

The lifetime cost of spinal cord injury in Ontario, Canada: A population-based study from the perspective of the public health care payer

223,801 per QALY gained. In sensitivity analyses, screening cost less than

Etanercept Patient Assistance Program: Another Data Source for EpidemiologicalStudies?

50,000 per QALY only if the probability of proximal DVT increased from a baseline of 8.5-16%. By comparison, increasing adherence to appropriate pharmacologic thromboprophylaxis by 10% resulted in 16 fewer DVTs, one fewer pulmonary emboli, and one additional heparin-induced thrombocytopenia and bleeding event, and cost

PCV81 Cost-Effectiveness of Ticagrelor Versus Clopidogrel in Patients with Acute Coronary Syndrome: Results from the Plato Study: A Canadian Analysis

27,953 per QALY gained. Programs achieving increased adherence to best-practice venous thromboembolism prevention were cost-effective over a wide range of program costs and were robust in probabilistic sensitivity analyses. CONCLUSIONS Appropriate prophylaxis provides better value in terms of costs and health gains than routine screening for DVT. Resources should be targeted at optimizing thromboprophylaxis.